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  • Jönsen, AndreasLund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Department of Rheumatology, Lund University, Lund, (author)

Direct and indirect costs for systemic lupus erythematosus in Sweden. A nationwide health economic study based on five defined cohorts

  • Article/chapterEnglish2016

Publisher, publication year, extent ...

  • Elsevier BV,2016
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:umu-124190
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-124190URI
  • https://doi.org/10.1016/j.semarthrit.2015.11.013DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-278033URI
  • https://lup.lub.lu.se/record/8592752URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-124004URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:133841729URI

Supplementary language notes

  • Language:English
  • Summary in:English

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Classification

  • Subject category:ref swepub-contenttype
  • Subject category:for swepub-publicationtype

Notes

  • Objectives: The main objectives of this study were to calculate total costs of illness and cost -driving disease features among patients with systemic lupus erythematosus (SLE) in Sweden. Methods: Five cohorts of well-defined SLE patients, located in different parts of the country were merged. Incident and prevalent cases from 2003 through 2010 were included. The American College of Rheumatology (ACR) classification criteria was used. From the local cohorts, data on demographics, disease activity (SLEDAI 2K), and organ damage (SDI) were collected. Costs for inpatient care, specialist outpatient care and drugs were retrieved from national registries at the National Board of Health and Welfare. Indirect costs were calculated based on sickness leave and disability pensions from the Swedish Social Insurance Agency. Results: In total, 1029 SLE patients, 88% females, were included, and approximately 75% were below 65 years at the end of follow-up, and thus in working age. The mean number of annual specialist physician visits varied from six to seven; mean annual inpatient days were 3.1-3.6, and mean annual sick leave was 123-148 days, all per patient. The total annual cost was 208,555 SEK ($33,369 = 22,941(sic)), of which direct cost was 63,672kr ($10,188 = 7004(sic)) and the indirect cost was 144,883 SEK ($23,181 = 15,937(sic)), all per patient. The costs for patients with short disease duration were higher. Higher disease activity as measured by a SLEDAI 2K score > 3 was associated with approximately 50% increase in both indirect and direct costs. Damage in the neuropsychiatric and musculoskeletal domains were also linked to higher direct and indirect costs, while organ damage in the renal and ocular systems increased direct costs. Conclusion: Based on this study and an estimate of slightly more than 6000 SLE patients in Sweden, the total annual cost for SLE in the country is estimated at $188 million (= 129.5 million (sic)). Both direct (30%) and indirect costs (70%) are substantial. Medication accounts for less than 10% of the total cost. The tax paid national systems for health care and social security in Sweden ensure equal access to health care, sick leave reimbursements, and disability pensions nationwide. Our extrapolated annual costs for SLE in Sweden are therefore the best supported estimations thus far, and they clearly underline the importance of improved management, especially to reduce the indirect costs. (C) 2016 Elsevier Inc. All rights reserved.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Hjalte, FridaThe Swedish Institute for Health Economics, Lund (author)
  • WILLIM, MINNALund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Lunds University, Lund(Swepub:lu)med-mwl (author)
  • Steen Carlsson, KatarinaLund University,Lunds universitet,Hälsoekonomi,Forskargrupper vid Lunds universitet,Health Economics,Lund University Research Groups,The Swedish Institute for Health Economics, Lund(Swepub:lu)smi-ks0 (author)
  • Sjöwall, ChristopherLinköpings universitet,Linköping University,Avdelningen för neuro- och inflammationsvetenskap,Medicinska fakulteten,Region Östergötland, Reumatologiska kliniken i Östergötland(Swepub:liu)chrsj93 (author)
  • Svenungsson, ElisabetKarolinska Institutet,Karolinska University Hospital, K, Karolinska Institutet, Stockholm (author)
  • Leonard, DagUppsala University,Uppsala universitet,Reumatologi,Department of Medical Sciences, Section of Rheumatology, Uppsala University, Uppsala, Sweden(Swepub:uu)dagle338 (author)
  • Bengtsson, ChristineUmeå University,Umeå universitet,Reumatologi,Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden(Swepub:umu)chbe0055 (author)
  • Rantapää-Dahlqvist, SolbrittUmeå University,Umeå universitet,Reumatologi,Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden(Swepub:umu)sora0001 (author)
  • Pettersson, SusanneKarolinska Institutet,Karolinska University Hospital, Karolinska Institutet, Stockholm (author)
  • Gunnarsson, IvaKarolinska Institutet,University Hospital, Karolinska Institutet, Stockholm (author)
  • Zickert, AgnetaKarolinska Institutet,University Hospital, Karolinska Institutet, Stockholm (author)
  • Gustafsson, Johanna T.Karolinska Institutet,University Hospital, Karolinska Institutet, Stockholm (author)
  • Rönnblom, LarsUppsala University,Uppsala universitet,Reumatologi,Department of Medical Sciences, Section of Rheumatology, Uppsala University, Uppsala, Sweden(Swepub:uu)larsronn (author)
  • Petersson, IngemarLund University,Lunds universitet,Ortopedi, Lund,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Orthopaedics (Lund),Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Department of Orthopedics, Lund University, Lund(Swepub:lu)ort-ipe (author)
  • Bengtsson, AndersLund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Department of Rheumatology, Lund University, Lund,(Swepub:lu)reum-abe (author)
  • Nived, OlaLund University,Lunds universitet,Reumatologi och molekylär skelettbiologi,Sektion III,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Rheumatology,Section III,Department of Clinical Sciences, Lund,Faculty of Medicine,Department of Rheumatology, Lund University, Lund,(Swepub:lu)reum-oni (author)
  • Reumatologi och molekylär skelettbiologiSektion III (creator_code:org_t)

Related titles

  • In:Seminars in Arthritis & Rheumatism: Elsevier BV45:6, s. 684-6900049-01721532-866X

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