SwePub
Sök i LIBRIS databas

  Extended search

(WFRF:(Kaaks Rudolf)) srt2:(2015-2019) pers:(Weiderpass Elisabete) pers:(Quirós J. Ramón)
 

Search: (WFRF:(Kaaks Rudolf)) srt2:(2015-2019) pers:(Weiderpass Elisabete) pers:(Quirós J. Ramón) > (2017) > Prediagnostic circu...

  • Perez-Cornago, AuroraUniversity of Oxford (author)

Prediagnostic circulating concentrations of plasma insulin-like growth factor-I and risk of lymphoma in the European Prospective Investigation into Cancer and Nutrition

  • Article/chapterEnglish2017

Publisher, publication year, extent ...

  • 2016-12-27
  • WILEY-BLACKWELL,2017
  • electronicrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:umu-132793
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-132793URI
  • https://doi.org/10.1002/ijc.30528DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:135207122URI
  • https://lup.lub.lu.se/record/855d905b-d6c5-4852-811a-7e86c4b441b6URI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Insulin-like growth factor (IGF)-I has cancer promoting activities. However, the hypothesis that circulating IGF-I concentration is related to risk of lymphoma overall or its subtypes has not been examined prospectively. IGF-I concentration was measured in pre-diagnostic plasma samples from a nested case-control study of 1,072 cases of lymphoid malignancies and 1,072 individually matched controls from the European Prospective Investigation into Cancer and Nutrition. Odds ratios (ORs) and confidence intervals (CIs) for lymphoma were calculated using conditional logistic regression. IGF-I concentration was not associated with overall lymphoma risk (multivariable-adjusted OR for highest versus lowest third = 0.77 [95% CI = 0.57-1.03], p(trend) = 0.06). There was no statistical evidence of heterogeneity in this association with IGF-I by sex, age at blood collection, time between blood collection and diagnosis, age at diagnosis, or body mass index (pheterogeneity for all >= 0.05). There were no associations between IGF-I concentration and risk for specific BCL subtypes, T-cell lymphoma or Hodgkin lymphoma, although number of cases were small. In this European population, IGF-I concentration was not associated with risk of overall lymphoma. This study provides the first prospective evidence on circulating IGF-I concentrations and risk of lymphoma. Further What's new? Insulin-like growth factor I does not appear to influence lymphoma risk, according to new results. IGF-I can promote some cancers, but there hasn't been a prospective epidemiological study examining the link between IGF-I concentration and lymphoma risk. To uncover a link, these authors arranged a NESTED case-control study with participants from the European Prospective Investigation into Cancer and Nutrition (EPIC). They tested for IGF-I in pre-diagnosis samples and found no association between the factor and overall lymphoma risk, nor with any subtype, although the number of cases was small for each subtype, and further studies are necessary.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Appleby, Paul N.University of Oxford (author)
  • Tipper, SarahUniversity of Oxford (author)
  • Key, Timothy J.University of Oxford (author)
  • Allen, Naomi E.University of Oxford (author)
  • Nieters, AlexandraUniversity Medical Center Freiburg (author)
  • Vermeulen, RoelUtrecht University (author)
  • Roulland, SandrineCentre d'Immunologie Marseille Luminy (author)
  • Casabonne, DelphineBellvitge Biomedical Research Institute (author)
  • Kaaks, RudolfGerman Cancer Research Centre (author)
  • Fortner, Renee T.German Cancer Research Centre (author)
  • Boeing, HeinerGerman Institute of Human Nutrition (author)
  • Trichopoulou, AntoniaNational and Kapodistrian University of Athens (author)
  • La Vecchia, CarloUniversity of Milan (author)
  • Klinaki, Eleni (author)
  • Hansen, LouiseDanish Cancer Society (author)
  • Tjonneland, AnneDanish Cancer Society (author)
  • Bonnet, FabriceRennes University Hospital (author)
  • Fagherazzi, GuyUniversity of Paris-Saclay (author)
  • Boutron-Ruault, Marie-ChristineUniversity of Paris-Saclay (author)
  • Pala, ValeriaIstituto Nazionale dei Tumori (author)
  • Masala, GiovannaCancer Research and Prevention Institute (ISPO) (author)
  • Sacerdote, CarlottaCitta' della Salute e della Scienza Hospital-University of Turin (author)
  • Peeters, Petra H.MRC Human Nutrition Research (author)
  • Bueno-de-Mesquita, H. B(as)University of Malaya (author)
  • Weiderpass, ElisabeteKarolinska Institutet,Folkhälsan Research Center (author)
  • Dorronsoro, MirenCIBER Epidemiology and Public Health (CIBERESP) (author)
  • Quiros, J. Ramon (author)
  • Barricarte, AurelioHealth Research Institute of Navarra (IDISNA) (author)
  • Gavrila, DianaMurcia Regional Health Council (author)
  • Agudo, AntonioBellvitge Biomedical Research Institute (author)
  • Borgquist, SigneLund University,Lunds universitet,Bröstcancer-genetik,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Breastcancer-genetics,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)ront-sbo (author)
  • Rosendahl, Ann H.Lund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)onk-aro (author)
  • Melin, BeatriceUmeå University,Umeå universitet,Onkologi(Swepub:umu)bema0010 (author)
  • Wareham, NickUniversity of Cambridge (author)
  • Khaw, Kay-TeeUniversity of Cambridge (author)
  • Gunter, MarcInternational Agency for Research on Cancer, World Health Organization (author)
  • Riboli, ElioImperial College London (author)
  • Vineis, PaoloImperial College London (author)
  • Travis, Ruth C.University of Oxford (author)
  • University of OxfordUniversity Medical Center Freiburg (creator_code:org_t)

Related titles

  • In:International Journal of Cancer: WILEY-BLACKWELL140:5, s. 1111-11180020-71361097-0215

Internet link

Find in a library

To the university's database

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view