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- Fallath, Thorya (author)
MEDIATOR18 and MEDIATOR20 confer susceptibility to Fusarium oxysporum in Arabidopsis thaliana
- Article/chapterEnglish2017
Publisher, publication year, extent ...
- 2017-04-25
- PUBLIC LIBRARY SCIENCE,2017
- electronicrdacarrier
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- LIBRIS-ID:oai:DiVA.org:umu-136206
- https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-136206URI
- https://doi.org/10.1371/journal.pone.0176022DOI
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- Language:English
- Summary in:English
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- SwePubSwePub
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- The conserved protein complex known as Mediator conveys transcriptional signals by acting as an intermediary between transcription factors and RNA polymerase II. As a result, Mediator subunits play multiple roles in regulating developmental as well as abiotic and biotic stress pathways. In this report we identify the head domain subunits MEDIATOR18 and MEDIATOR20 as important susceptibility factors for Fusarium oxysporum infection in Arabidopsis thaliana. Mutants of MED18 and MED20 display down-regulation of genes associated with jasmonate signaling and biosynthesis while up-regulation of salicylic acid associated pathogenesis related genes and reactive oxygen producing and scavenging genes. We propose that MED18 and MED20 form a sub-domain within Mediator that controls the balance of salicylic acid and jasmonate associated defense pathways.
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- Kidd, Brendan N. (author)
- Stiller, Jiri (author)
- Davoine, CelineUmeå universitet,Institutionen för medicinsk kemi och biofysik,Umeå Plant Science Centre (UPSC)(Swepub:umu)ceda0002 (author)
- Björklund, StefanUmeå universitet,Institutionen för medicinsk kemi och biofysik,Umeå Plant Science Centre (UPSC)(Swepub:umu)stbj0001 (author)
- Manners, John M. (author)
- Kazan, Kemal (author)
- Schenk, Peer M. (author)
- Umeå universitetInstitutionen för medicinsk kemi och biofysik (creator_code:org_t)
Related titles
- In:PLOS ONE: PUBLIC LIBRARY SCIENCE12:41932-6203
Internet link
- https://doi.org/10.1371/journal.pone.0176022Fulltext
- https://umu.diva-portal.org/smash/get/diva2:1118925/FULLTEXT01.pdffulltext:print
- https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0176022&type=printable
- https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-136206
- https://doi.org/10.1371/journal.pone.0176022
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