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Neutralizing VEGF bioactivity with a soluble chimeric VEGF-receptor protein flt(1-3)IgG inhibits testosterone-stimulated prostate growth in castrated mice.

Lissbrant, Ingela Franck (author)
Umeå universitet,Institutionen för medicinsk biovetenskap
Hammarsten, Peter (author)
Umeå universitet,Patologi
Lissbrant, Erik (author)
Umeå universitet,Institutionen för medicinsk biovetenskap
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Ferrara, Napoleone (author)
Rudolfsson, Stina Häggström (author)
Umeå universitet,Urologi och andrologi
Bergh, Anders (author)
Umeå universitet,Patologi
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 (creator_code:org_t)
Wiley, 2004
2004
English.
In: Prostate. - : Wiley. - 0270-4137. ; 58:1, s. 57-65
  • Journal article (peer-reviewed)
Subject headings
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Keyword

Animals
Apoptosis/drug effects/physiology
Bromodeoxyuridine/metabolism
Castration
Cell Division/drug effects
Endothelial Cells/cytology/drug effects/metabolism
Immunoglobulin G/pharmacology
Immunohistochemistry
Male
Mice
Mice; Inbred C57BL
Neovascularization; Physiologic/physiology
Organ Size/drug effects
Prostate/blood supply/cytology/*drug effects/metabolism
Receptors; Androgen/metabolism
Recombinant Fusion Proteins/metabolism/pharmacology
Testosterone/antagonists & inhibitors/metabolism/*pharmacology
Vascular Endothelial Growth Factor A/*antagonists & inhibitors/metabolism
Vascular Endothelial Growth Factor Receptor-1/*administration & dosage

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