SwePub
Sök i LIBRIS databas

  Utökad sökning

WFRF:(David Audrey)
 

Sökning: WFRF:(David Audrey) > Skin colour changes...

  • Henderson, Audrey J. (författare)

Skin colour changes during experimentally-induced sickness

  • Artikel/kapitelEngelska2017

Förlag, utgivningsår, omfång ...

  • Elsevier BV,2017
  • printrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:su-137352
  • https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-137352URI
  • https://doi.org/10.1016/j.bbi.2016.11.008DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:134978626URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Skin colour may be an important cue to detect sickness in humans but how skin colour changes with acute sickness is currently unknown. To determine possible colour changes, 22 healthy Caucasian participants were injected twice, once with lipopolysaccharide (LPS, at a dose of 2ng/kg body weight) and once with placebo (saline), in a randomised cross-over design study. Skin colour across 3 arm and 3 face locations was recorded spectrophotometrically over a period of 8h in terms of lightness (L(∗)), redness (a(∗)) and yellowness (b(∗)) in a manner that is consistent with human colour perception. In addition, carotenoid status was assessed as we predicted that a decrease it skin yellowness would reflect a drop in skin carotenoids. We found an early change in skin colouration 1-3h post LPS injection with facial skin becoming lighter and less red whilst arm skin become darker but also less red and less yellow. The LPS injection also caused a drop in plasma carotenoids from 3h onwards. However, the timing of the carotenoid changes was not consistent with the skin colour changes suggesting that other mechanisms, such as a reduction of blood perfusion, oxygenation or composition. This is the first experimental study characterising skin colour associated with acute illness, and shows that changes occur early in the development of the sickness response. Colour changes may serve as a cue to health, prompting actions from others in terms of care-giving or disease avoidance. Specific mechanisms underlying these colour changes require further investigation.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Lasselin, JulieStockholms universitet,Stressforskningsinstitutet,Karolinska Institutet, Sweden; Institute of Medical Psychology and Behavioral Immunobiology, Germany(Swepub:su)jlass (författare)
  • Lekander, MatsStockholms universitet,Stressforskningsinstitutet,Karolinska Institutet, Sweden(Swepub:su)mleka (författare)
  • Olsson, Mats J.Karolinska Institutet (författare)
  • Powis, Simon J. (författare)
  • Axelsson, JohnStockholms universitet,Stressforskningsinstitutet,Karolinska Institutet, Sweden(Swepub:su)jaxel (författare)
  • Perrett, David I. (författare)
  • Stockholms universitetStressforskningsinstitutet (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Brain, behavior, and immunity: Elsevier BV60, s. 312-3180889-15911090-2139

Internetlänk

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy