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Lifetime and baseli...
Lifetime and baseline alcohol intakes and risk of pancreatic cancer in the European Prospective Investigation into Cancer and Nutrition study
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- Naudin, Sabine (författare)
- International Agency for Research on Cancer, World Health Organization
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- Li, Kuanrong (författare)
- International Agency for Research on Cancer, World Health Organization
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- Jaouen, Tristan (författare)
- International Agency for Research on Cancer, World Health Organization
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visa fler...
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- Assi, Nada (författare)
- International Agency for Research on Cancer, World Health Organization
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- Kyrø, Cecilie (författare)
- Danish Cancer Society
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- Tjønneland, Anne (författare)
- Danish Cancer Society
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- Overvad, Kim (författare)
- Aarhus University
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Boutron-Ruault, Marie-Christine (författare)
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Rebours, Vinciane (författare)
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Védié, Anne-Laure (författare)
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- Boeing, Heiner (författare)
- German Institute of Human Nutrition
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- Kaaks, Rudolf (författare)
- German Cancer Research Centre
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- Katzke, Verena (författare)
- German Cancer Research Centre
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Bamia, Christina (författare)
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Naska, Androniki (författare)
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Trichopoulou, Antonia (författare)
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- Berrino, Franco (författare)
- Istituto Nazionale dei Tumori
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- Tagliabue, Giovanna (författare)
- Istituto Nazionale dei Tumori
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- Palli, Domenico (författare)
- Cancer Research and Prevention Institute (ISPO)
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- Panico, Salvatore (författare)
- University of Naples Federico II
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- Tumino, Rosario (författare)
- Civic and M.P Arezzo Hospital
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- Sacerdote, Carlotta (författare)
- Citta' della Salute e della Scienza Hospital-University of Turin
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- Peeters, Petra H (författare)
- University Medical Center Utrecht,Imperial College London
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- Bueno-de-Mesquita, Bas (författare)
- National Institute for Public Health and the Environment (RIVM),Imperial College London,University of Malaya
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- Weiderpass Vainio, Elisabete (författare)
- Karolinska Institutet,Karolinska Institute,Cancer Registry of Norway, Institute of Population-Based Cancer Research,UiT The Arctic University of Norway, Tromsø,Folkhälsan Research Center
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- Gram, Inger Torhild (författare)
- UiT The Arctic University of Norway, Tromsø
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- Skeie, Guri (författare)
- UiT The Arctic University of Norway, Tromsø
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- Chirlaque, Maria-Dolores (författare)
- University of Murcia,Murcia Regional Health Council,CIBER Epidemiology and Public Health (CIBERESP)
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- Rodríguez-Barranco, Miguel (författare)
- University of Granada,CIBER Epidemiology and Public Health (CIBERESP)
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- Barricarte, Aurelio (författare)
- CIBER Epidemiology and Public Health (CIBERESP),Navara Public Health Institute,Health Research Institute of Navarra (IDISNA)
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- Quirós, Jose Ramón (författare)
- Public Health Directorate
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Dorronsoro, Miren (författare)
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- Johansson, Ingegerd (författare)
- Umeå University,Umeå universitet,Institutionen för odontologi
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- Sund, Malin (författare)
- Umeå University,Umeå universitet,Kirurgi
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- Sternby, Hanna (författare)
- Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups
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- Bradbury, Kathryn E (författare)
- University of Oxford
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- Wareham, Nick (författare)
- University of Cambridge
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- Riboli, Elio (författare)
- Imperial College London
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- Gunter, Marc (författare)
- International Agency for Research on Cancer, World Health Organization
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- Brennan, Paul (författare)
- International Agency for Research on Cancer, World Health Organization
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- Duell, Eric J (författare)
- Bellvitge Biomedical Research Institute
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- Ferrari, Pietro (författare)
- International Agency for Research on Cancer, World Health Organization
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(creator_code:org_t)
- 2018-03-30
- 2018
- Engelska.
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Ingår i: International Journal of Cancer. - : Wiley. - 0020-7136 .- 1097-0215. ; 143:4, s. 801-812
- Relaterad länk:
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https://onlinelibrar...
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visa fler...
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://lup.lub.lu.s...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Recent evidence suggested a weak relationship between alcohol consumption and pancreatic cancer (PC) risk. In our study, the association between lifetime and baseline alcohol intakes and the risk of PC was evaluated, including the type of alcoholic beverages and potential interaction with smoking. Within the European Prospective Investigation into Cancer and Nutrition (EPIC) study, 1,283 incident PC (57% women) were diagnosed from 476,106 cancer-free participants, followed up for 14 years. Amounts of lifetime and baseline alcohol were estimated through lifestyle and dietary questionnaires, respectively. Cox proportional hazard models with age as primary time variable were used to estimate PC hazard ratios (HR) and their 95% confidence interval (CI). Alcohol intake was positively associated with PC risk in men. Associations were mainly driven by extreme alcohol levels, with HRs comparing heavy drinkers (>60 g/day) to the reference category (0.1-4.9 g/day) equal to 1.77 (95% CI: 1.06, 2.95) and 1.63 (95% CI: 1.16, 2.29) for lifetime and baseline alcohol, respectively. Baseline alcohol intakes from beer (>40 g/day) and spirits/liquors (>10 g/day) showed HRs equal to 1.58 (95% CI: 1.07, 2.34) and 1.41 (95% CI: 1.03, 1.94), respectively, compared to the reference category (0.1-2.9 g/day). In women, HR estimates did not reach statistically significance. The alcohol and PC risk association was not modified by smoking status. Findings from a large prospective study suggest that baseline and lifetime alcohol intakes were positively associated with PC risk, with more apparent risk estimates for beer and spirits/liquors than wine intake.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
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Naudin, Sabine
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Li, Kuanrong
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Jaouen, Tristan
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Assi, Nada
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Kyrø, Cecilie
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Tjønneland, Anne
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visa fler...
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Overvad, Kim
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Boutron-Ruault, ...
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Rebours, Vincian ...
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Védié, Anne-Laur ...
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Boeing, Heiner
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Kaaks, Rudolf
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Katzke, Verena
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Bamia, Christina
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Naska, Androniki
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Trichopoulou, An ...
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Berrino, Franco
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Tagliabue, Giova ...
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Palli, Domenico
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Panico, Salvator ...
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Tumino, Rosario
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Sacerdote, Carlo ...
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Peeters, Petra H
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Bueno-de-Mesquit ...
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Weiderpass Vaini ...
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Gram, Inger Torh ...
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Skeie, Guri
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Chirlaque, Maria ...
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Rodríguez-Barran ...
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Barricarte, Aure ...
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Quirós, Jose Ram ...
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Dorronsoro, Mire ...
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Johansson, Ingeg ...
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Sund, Malin
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Sternby, Hanna
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Bradbury, Kathry ...
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Wareham, Nick
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Riboli, Elio
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Gunter, Marc
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Brennan, Paul
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Duell, Eric J
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Ferrari, Pietro
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och Klinisk medicin
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International Jo ...
- Av lärosätet
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Umeå universitet
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Lunds universitet
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Karolinska Institutet