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Quality of life aft...
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Näverlo, SimonUmeå universitet,Kirurgi
(author)
Quality of life after end colostomy without mesh and with prophylactic synthetic mesh in sublay position : one-year results of the STOMAMESH trial
- Article/chapterEnglish2019
Publisher, publication year, extent ...
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2019-08-07
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Springer,2019
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electronicrdacarrier
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LIBRIS-ID:oai:DiVA.org:umu-164507
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-164507URI
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https://doi.org/10.1007/s00384-019-03359-2DOI
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
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Purpose: To determine whether prophylactic mesh in a sublay position has an impact on the quality-of-life (QoL) of patients receiving an end colostomy.Methods: One-year follow-up of patients from the STOMAMESH trial, a randomized controlled double-blinded multicenter study. Patients were randomized to either prophylactic synthetic mesh with a cruciform incision in the center, placed in sublay position, or no prophylactic mesh. Patients attended a 1-year visit and responded to the questionnaires EORTC QLQ C-30 and CR-38. The impact of having a mesh on QoL was determined by comparing a group of patients receiving a mesh with a group without. A subgroup analysis was made depending on whether a PSH was clinically present or not.Results: Of the 232 randomized patients, 211 patients reached the 1-year clinical follow-up. The response rate of these 211 patients was 70%. No differences were seen in global QoL between the groups. Mesh patients reported significantly less stoma-related problems (p = 0.014) but more sexual problems in males (p = 0.022). When excluding patients with a clinical diagnosis of PSH, the difference in stoma-related problems remained while no significant difference was seen regarding sexual problems in males.Conclusions: When forming an end colostomy, prophylactic synthetic mesh in a sublay position did not affect global QoL at 1-year follow-up, but stoma-related problems were fewer even in the presence of a clinically diagnosed PSH.
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Gunnarsson, UlfUmeå universitet,Kirurgi(Swepub:umu)ulgu0014
(author)
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Strigård, KarinUmeå universitet,Kirurgi(Swepub:umu)kast0065
(author)
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Näsvall, PiaSunderby Research Unit, Umeå University, Luleå, Sweden
(author)
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Umeå universitetKirurgi
(creator_code:org_t)
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In:International Journal of Colorectal Disease: Springer34:9, s. 1591-15990179-19581432-1262
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