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WFRF:(Wennstig Anna Karin 1973 )
 

Sökning: WFRF:(Wennstig Anna Karin 1973 ) > Risk of primary lun...

Risk of primary lung cancer after adjuvant radiotherapy in breast cancer : a large population-based study

Wennstig, Anna-Karin, 1973- (författare)
Umeå universitet,Kirurgi,Department of Oncology, Sundsvall Hospital, Sundsvall, Sweden,Umeå Univ, Dept Surg & Perioperat Sci, Umeå, Sweden; Sundsvall Hosp, Dept Oncol, Sundsvall, Sweden
Wadsten, Charlotta (författare)
Umeå universitet,Kirurgi,Department of Surgery, Sundsvall Hospital, Sundsvall, Sweden,Umeå Univ, Dept Surg & Perioperat Sci, Umeå, Sweden; Sundsvall Hosp, Dept Surg, Sundsvall, Sweden
Garmo, Hans (författare)
Regional Cancer Center, Uppsala University/ Uppsala University Hospital
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Johansson, Mikael (författare)
Umeå universitet,Onkologi,Umeå Univ, Dept Radiat Sci, Umeå, Sweden
Fredriksson, Irma (författare)
Karolinska Institutet,Karolinska Univ Hosp, Dept Breast & Endocrine Surg, Stockholm, Sweden; Karolinska Inst, Dept Mol Med & Surg, Stockholm, Sweden,Department of Breast-and Endocrine Surgery, Karolinska University Hospital. Department of Molecular Medicine and Surgery, Karolinska Institutet,
Blomqvist, Carl (författare)
Department of Oncology, Örebro University, University Hospital,Örebro Univ, Univ Hosp, Dept Oncol, Örebro, Sweden
Holmberg, Lars (författare)
Uppsala universitet,Endokrinkirurgi,Kings Coll London, Sch Canc & Pharmaceut Sci, Translat Oncol & Urol Res TOUR, London, England,Translational Oncology & Urology Research (TOUR), School of Cancer and Pharmaceutical Sciences, King’s College London, London, UK. Department of Surgical Sciences, Uppsala University
Nilsson, Greger (författare)
Uppsala universitet,Experimentell och klinisk onkologi,Gävle Cent Hosp, Dept Oncol, Gävle, Sweden; Visby Hosp, Dept Oncol, Visby, Sweden,Department of Immunology, Genetics and Pathology, Section of Experimental and Clinical Oncology, Uppsala University, University Hospital,
Sund, Malin (författare)
Umeå universitet,Kirurgi,Umeå Univ, Dept Surg & Perioperat Sci, Umeå, Sweden
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 (creator_code:org_t)
2021-06-01
2021
Engelska.
Ingår i: npj Breast Cancer. - : Springer Nature. - 2374-4677. ; 7:1
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Adjuvant radiotherapy (RT) for breast cancer (BC) has been associated with an increased risk of later radiation-induced lung cancer (LC). We examined the risk of primary LC in a population-based cohort of 52300 women treated for BC during 1992 to 2012, and 253796 age-matched women without BC. Cumulative incidence of LC was calculated by the Kaplan–Meier method, and the risk of LC after BC treatment was estimated by Cox proportional hazards regression analyses. Women with BC receiving RT had a higher cumulative incidence of LC compared to women with BC not receiving RT and women without BC. This became apparent 5 years after RT and increased with longer follow-up. Women with BC receiving RT had a Hazard ratio of 1.59 (95% confidence interval 1.37–1.84) for LC compared to women without BC. RT techniques that lower the incidental lung doses, e.g breathing adaption techniques, may lower this risk.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)

Nyckelord

Oncology
onkologi

Publikations- och innehållstyp

ref (ämneskategori)
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