Search: (L773:1097 0215) pers:(Sacerdote Carlotta) pers:(Rinaldi Sabina) >
Exogenous hormone u...
Exogenous hormone use and cutaneous melanoma risk in women : The European Prospective Investigation into Cancer and Nutrition
-
- Cervenka, Iris (author)
- Institut Gustave Roussy,University of Paris-Saclay
-
Al Rahmoun, Marie (author)
-
Mahamat-Saleh, Yahya (author)
-
show more...
-
Fournier, Agnes (author)
-
Boutron-Ruault, Marie-Christine (author)
-
Severi, Gianluca (author)
-
Caini, Saverio (author)
-
Palli, Domenico (author)
-
Ghiasvand, Reza (author)
-
Veierod, Marit B. (author)
-
Botteri, Edoardo (author)
-
Tjonneland, Anne (author)
-
Olsen, Anja (author)
-
Fortner, Renee T. (author)
-
Kaaks, Rudolf (author)
-
Schulze, Matthias B. (author)
-
Panico, Salvatore (author)
-
Trichopoulou, Antonia (author)
-
Dessinioti, Clio (author)
-
Niforou, Katerina (author)
-
Sieri, Sabina (author)
-
Tumino, Rosario (author)
-
Sacerdote, Carlotta (author)
-
Bueno-de-Mesquita, Bas (author)
-
Sandanger, Torkjel M. (author)
-
Colorado-Yohar, Sandra (author)
-
Sanchez, Maria J. (author)
-
Gil Majuelo, Leire (author)
-
Lujan-Barroso, Leila (author)
-
Ardanaz, Eva (author)
-
Merino, Susana (author)
-
- Isaksson, Karolin (author)
- Lund University,Lunds universitet,Lunds Melanomstudiegrupp,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Lund Melanoma Study Group,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital
-
- Butt, Salma (author)
- Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups
-
Ljuslinder, Ingrid (author)
-
- Jansson, Malin (author)
- Umeå universitet,Kirurgi
-
Travis, Ruth C. (author)
-
Khaw, Kay-Tee (author)
-
Weiderpass, Elisabete (author)
-
Dossus, Laure (author)
-
Rinaldi, Sabina (author)
-
- Kvaskoff, Marina (author)
- University of Paris-Saclay,Institut Gustave Roussy
-
show less...
-
(creator_code:org_t)
-
et al
- 2019-10-10
- 2020
- English.
-
In: International Journal of Cancer. - : John Wiley & Sons. - 0020-7136 .- 1097-0215. ; 146:12, s. 3267-3280
- Related links:
-
https://onlinelibrar...
-
show more...
-
http://dx.doi.org/10...
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
https://lup.lub.lu.s...
-
show less...
Abstract
Subject headings
Close
- Evidence suggests an influence of sex hormones on cutaneous melanoma risk, but epidemiologic findings are conflicting. We examined the associations between use of oral contraceptives (OCs) and menopausal hormone therapy (MHT) and melanoma risk in women participating in the European Prospective Investigation into Cancer and Nutrition (EPIC). EPIC is a prospective cohort study initiated in 1992 in 10 European countries. Information on exogenous hormone use at baseline was derived from country‐specific self‐administered questionnaires. We used Cox proportional hazards regression models to calculate hazard ratios (HRs) and 95% confidence intervals (CIs). Over 1992–2015, 1,696 melanoma cases were identified among 334,483 women, whereof 770 cases among 134,758 postmenopausal women. There was a positive, borderline‐significant association between OC use and melanoma risk (HR = 1.12, 95% CI = 1.00–1.26), with no detected heterogeneity across countries (phomogeneity = 0.42). This risk increased linearly with duration of use (ptrend = 0.01). Among postmenopausal women, ever use of MHT was associated with a nonsignificant increase in melanoma risk overall (HR = 1.14, 95% CI = 0.97–1.43), which was heterogeneous across countries (phomogeneity = 0.05). Our findings do not support a strong and direct association between exogenous hormone use and melanoma risk. In order to better understand these relations, further research should be performed using prospectively collected data including detailed information on types of hormone, and on sun exposure, which may act as an important confounder or effect modifier on these relations.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Keyword
- cohort studies
- cutaneous melanoma
- epidemiology
- hormonal treatments
- menopausal hormone therapy
- oral contraceptives
- cohort studies
- cutaneous melanoma
- epidemiology
- hormonal treatments
- menopausal hormone therapy
- oral contraceptives
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
-
Cervenka, Iris
-
Al Rahmoun, Mari ...
-
Mahamat-Saleh, Y ...
-
Fournier, Agnes
-
Boutron-Ruault, ...
-
Severi, Gianluca
-
show more...
-
Caini, Saverio
-
Palli, Domenico
-
Ghiasvand, Reza
-
Veierod, Marit B ...
-
Botteri, Edoardo
-
Tjonneland, Anne
-
Olsen, Anja
-
Fortner, Renee T ...
-
Kaaks, Rudolf
-
Schulze, Matthia ...
-
Panico, Salvator ...
-
Trichopoulou, An ...
-
Dessinioti, Clio
-
Niforou, Katerin ...
-
Sieri, Sabina
-
Tumino, Rosario
-
Sacerdote, Carlo ...
-
Bueno-de-Mesquit ...
-
Sandanger, Torkj ...
-
Colorado-Yohar, ...
-
Sanchez, Maria J ...
-
Gil Majuelo, Lei ...
-
Lujan-Barroso, L ...
-
Ardanaz, Eva
-
Merino, Susana
-
Isaksson, Karoli ...
-
Butt, Salma
-
Ljuslinder, Ingr ...
-
Jansson, Malin
-
Travis, Ruth C.
-
Khaw, Kay-Tee
-
Weiderpass, Elis ...
-
Dossus, Laure
-
Rinaldi, Sabina
-
Kvaskoff, Marina
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Cancer and Oncol ...
- Articles in the publication
-
International Jo ...
- By the university
-
Umeå University
-
Lund University