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  • Cronberg, OlofLund University,Lunds universitet,Allmänmedicin och samhällsmedicin,Forskargrupper vid Lunds universitet,Family Medicine and Community Medicine,Lund University Research Groups,Region Kronoberg,VC Vaxjohalsan, Sweden; Dept Res & Dev, Sweden; Lund Univ, Sweden (författare)

Diagnosis-linked antibiotic prescribing in Swedish primary care : a comparison between in-hours and out-of-hours

  • Artikel/kapitelEngelska2020

Förlag, utgivningsår, omfång ...

  • 2020-08-20
  • BioMed Central,2020
  • electronicrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:umu-175811
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-175811URI
  • https://doi.org/10.1186/s12879-020-05334-7DOI
  • https://lup.lub.lu.se/record/72228725-f12e-4d5c-84c3-ee30d2ca7061URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-170686URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

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  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Funding Agencies|RD Kronoberg; Region Kronoberg; Medical Research Council of Southeast Sweden (FORSS); Southern Regional Health Care Committee, Sweden; Lund University
  • Background: The rise in antibiotic resistance is a global public health concern, and antibiotic overuse needs to be reduced. Earlier studies of out-of-hours care have indicated that antibiotic prescribing is less appropriate than that of in-hours care. However, no study has compared the out-of-hours treatment of infections to in-hours treatment within the same population.Methods: This retrospective, descriptive study was based on data retrieved from the Kronoberg Infection Database in Primary Care (KIDPC), which consists of all visits to primary care with an infection diagnosis or prescription of antibiotics during 2006-2014. The purpose was to study the trends in antibiotic prescribing and to compare consultations and prescriptions between in-hours and out-of-hours.Results: The visit rate for all infections was 434 visits per 1000 inhabitants per year. The visit rate was stable during the study period, but the antibiotic prescribing rate decreased from 266 prescriptions per 1000 inhabitants in 2006 to 194 prescriptions in 2014 (mean annual change - 8.5 [95% CI - 11.9 to - 5.2]). For the out-of-hours visits (12% of the total visits), a similar reduction in antibiotic prescribing was seen. The decrease was most apparent among children and in respiratory tract infections. When antibiotic prescribing during out-of-hours was compared to in-hours, the unadjusted relative risk of antibiotic prescribing was 1.37 (95% CI 1.36 to 1.38), but when adjusted for age, sex, and diagnosis, the relative risk of antibiotic prescribing was 1.09 (95% CI 1.08 to 1.10). The reduction after adjustment was largely explained by a higher visit rate during out-of-hours for infections requiring antibiotics (acute otitis media, pharyngotonsillitis, and lower urinary tract infection). The choices of antibiotics used for common diagnoses were similar.Conclusions: Although the infection visit rate was unchanged over the study period, there was a significant reduction in antibiotic prescribing, especially to children and for respiratory tract infections. The higher antibiotic prescribing rate during out-of-hours was small when adjusted for age, sex, and diagnosis. No excess prescription of broad-spectrum antibiotics was seen. Therefore, interventions selectively aiming at out-of-hours centres seem to be unmotivated in a low-prescribing context.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Tyrstrup, MiaLund University,Lunds universitet,Allmänmedicin och samhällsmedicin,Forskargrupper vid Lunds universitet,Family Medicine and Community Medicine,Lund University Research Groups,Center for Primary Health Care Research,Lund Univ, Sweden; Lundbergsgatan Primary Hlth Care Ctr, Sweden(Swepub:lu)med-mty (författare)
  • Ekblom, Kim,1970-Umeå University,Umeå universitet,Klinisk kemi,Department of Research and Development, Region Kronoberg, Växjö, Sweden,Dept Res & Dev, Region Kronoberg, Växjö, Sweden; Umea Univ, Sweden(Swepub:umu)kimekm00 (författare)
  • Hedin, KatarinaLinköpings universitet,Linköping University,Lund University,Lunds universitet,Allmänmedicin och samhällsmedicin,Forskargrupper vid Lunds universitet,Family Medicine and Community Medicine,Lund University Research Groups,Avdelningen för prevention, rehabilitering och nära vård,Medicinska fakulteten,Lund Univ, Sweden(Swepub:liu)kathe53 (författare)
  • Allmänmedicin och samhällsmedicinForskargrupper vid Lunds universitet (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:BMC Infectious Diseases: BioMed Central20:11471-2334

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