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A Body Shape Index ...
A Body Shape Index (ABSI) achieves better mortality risk stratification than alternative indices of abdominal obesity : results from a large European cohort
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- Christakoudi, Sofia (author)
- King's College London,Imperial College London,Imperial Coll London, Dept Epidemiol & Biostat, Norfolk Pl,St Marys Campus, London W2 1PG, England.;Kings Coll London, MRC Ctr Transplantat, London SE1 9RT, England.
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- Tsilidis, Konstantinos K. (author)
- University of Ioannina,Imperial College London,Imperial Coll London, Dept Epidemiol & Biostat, Norfolk Pl,St Marys Campus, London W2 1PG, England.;Univ Ioannina, Sch Med, Dept Hyg & Epidemiol, Ioannina 45100, Greece.
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- Muller, David C. (author)
- Imperial College London,Imperial Coll London, Dept Epidemiol & Biostat, Norfolk Pl,St Marys Campus, London W2 1PG, England.
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- Freisling, Heinz (author)
- International Agency for Research on Cancer, World Health Organization,WHO, Int Agcy Res Canc, 150 Cours Albert Thomas, F-69372 Lyon 08, France.
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- Weiderpass, Elisabete (author)
- International Agency for Research on Cancer, World Health Organization,WHO, Int Agcy Res Canc, 150 Cours Albert Thomas, F-69372 Lyon 08, France.
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- Overvad, Kim (author)
- Aalborg University Hospital,Aarhus University,Aarhus Univ, Dept Publ Hlth, DK-8000 Aarhus, Denmark.;Aalborg Univ Hosp, Dept Cardiol, DK-9000 Aalborg, Denmark.
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- Söderberg, Stefan (author)
- Umeå University,Umeå universitet,Kardiologi,Umeå Univ, Dept Publ Hlth & Clin Med, Umeå, Sweden.
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- Häggström, Christel (author)
- Uppsala universitet,Uppsala University,Umeå University,Umeå universitet,Enheten för biobanksforskning,Department of Surgical Sciences, Uppsala University, Uppsala, Sweden,Institutionen för kirurgiska vetenskaper,Umeå Univ, Dept Biobank Res, Umeå, Sweden
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- Pischon, Tobias (author)
- Charité - University Medicine Berlin,Max Delbrück Center for Molecular Medicine (MDC),Max Delbruck Ctr Mol Med, D-13125 Berlin, Germany.;Charite Univ Med Berlin, Berlin, Germany.;Berlin Inst Hlth BIH, Berlin, Germany.
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- Dahm, Christina C. (author)
- Aarhus University,Aarhus Univ, Dept Publ Hlth, DK-8000 Aarhus, Denmark.
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- Zhang, Jie (author)
- Aarhus University,Aarhus Univ, Dept Publ Hlth, DK-8000 Aarhus, Denmark.
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- Tjonneland, Anne (author)
- University of Copenhagen,Danish Cancer Society,Danish Canc Soc Res Ctr, Strandboulevarden 49, DK-2100 Copenhagen O, Denmark.;Univ Copenhagen, Dept Publ Hlth, Copenhagen, Denmark.
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- Halkjaer, Jytte (author)
- Danish Cancer Society,Danish Canc Soc Res Ctr, Strandboulevarden 49, DK-2100 Copenhagen O, Denmark.
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- MacDonald, Conor (author)
- Centre for Research in Epidemiology and Population Health (CESP),Stabilite genetique et oncogenese,Univ Paris Saclay, Univ Paris Sud, Ctr Rech Epidemiol & Sante Populat CESP, Fac Med,UVSQ,INSERM, F-94805 Villejuif, France.;Gustave Roussy, F-94805 Villejuif, France.
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- Boutron-Ruault, Marie-Christine (author)
- Stabilite genetique et oncogenese,Centre for Research in Epidemiology and Population Health (CESP),Univ Paris Saclay, Univ Paris Sud, Ctr Rech Epidemiol & Sante Populat CESP, Fac Med,UVSQ,INSERM, F-94805 Villejuif, France.;Gustave Roussy, F-94805 Villejuif, France.
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- Mancini, Francesca Romana (author)
- Centre for Research in Epidemiology and Population Health (CESP),Stabilite genetique et oncogenese,Univ Paris Saclay, Univ Paris Sud, Ctr Rech Epidemiol & Sante Populat CESP, Fac Med,UVSQ,INSERM, F-94805 Villejuif, France.;Gustave Roussy, F-94805 Villejuif, France.
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- Kuehn, Tilman (author)
- German Cancer Research Centre,German Canc Res Ctr, Div Canc Epidemiol, Heidelberg, Germany.
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- Kaaks, Rudolf (author)
- German Cancer Research Centre,German Canc Res Ctr, Div Canc Epidemiol, Heidelberg, Germany.
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- Schulze, Matthias B. (author)
- University of Potsdam,German Institute of Human Nutrition,German Inst Human Nutr Potsdam Rehbrucke, Dept Mol Epidemiol, Nuthetal, Germany.;Univ Potsdam, Inst Nutr Sci, Nuthetal, Germany.
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- Trichopoulou, Antonia (author)
- Hellenic Health Foundation, Athens,Hellen Hlth Fdn, Athens, Greece.
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- Karakatsani, Anna (author)
- Hellenic Health Foundation, Athens,National and Kapodistrian University of Athens,Hellen Hlth Fdn, Athens, Greece.;Natl & Kapodistrian Univ Athens, ATTIKON Univ Hosp, Sch Med, Dept Pulm Med 2, Haidari, Greece.
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- Peppa, Eleni (author)
- Hellenic Health Foundation, Athens,Hellen Hlth Fdn, Athens, Greece.
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- Masala, Giovanna (author)
- Institute for Cancer Research, Prevention and Clinical Network (ISPRO),Inst Canc Res Prevent & Clin Network ISPRO, Canc Risk Factors & Life Style Epidemiol Unit, Florence, Italy.
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- Pala, Valeria (author)
- Istituto Nazionale dei Tumori,Fdn IRCCS Ist Nazl Tumori Milano, Epidemiol & Prevent Unit, Via Venezian,1, I-20133 Milan, Italy.
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- Panico, Salvatore (author)
- University of Naples Federico II,Univ Naples Federico II, Dipartimento Med Clin & Chirurg, Naples, Italy.
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- Tumino, Rosario (author)
- Civic and M.P Arezzo Hospital,Azienda Sanit Prov Ragusa ASP, Canc Registry, Ragusa, Italy.;Azienda Sanit Prov Ragusa ASP, Dept Histopathol, Ragusa, Italy.
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- Sacerdote, Carlotta (author)
- Citta' della Salute e della Scienza Hospital-University of Turin,Citta Salute & Sci Univ Hosp, Unit Canc Epidemiol, Turin, Italy.;Ctr Canc Prevent CPO, Turin, Italy.
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- Quiros, J. Ramon (author)
- Publ Hlth Directorate, Asturias, Spain.
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- Agudo, Antonio (author)
- Catalan Institute of Oncology,Imperial College London,Catalan Inst Oncol IDIBELL, Unit Nutr & Canc, Canc Epidemiol Res Program, Barcelona, Spain.,Imperial Coll London, Dept Epidemiol & Biostat, Norfolk Pl,St Marys Campus, London W2 1PG, England.
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- Sanchez, Maria-Jose (author)
- CIBER Epidemiology and Public Health (CIBERESP),University of Granada,Andalusian School Of Public Health (EASP),Andalusian Sch Publ Hlth EASP, Granada, Spain.;Inst Invest Biosanitaria Granada Ibs GRANADA, Granada, Spain.;Univ Granada, Granada, Spain.;CIBER Epidemiol & Publ Hlth CIBERESP, Madrid, Spain.
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- Cirera, Lluis (author)
- University of Murcia,CIBER Epidemiology and Public Health (CIBERESP),Murcia Regional Health Council,CIBER Epidemiol & Publ Hlth CIBERESP, Madrid, Spain.;IMIB Arrixaca, Murcia Reg Hlth Council, Dept Epidemiol, Murcia, Spain.;Univ Murcia, Dept Hlth & Social Sci, Murcia, Spain.
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- Barricarte-Gurrea, Aurelio (author)
- CIBER Epidemiology and Public Health (CIBERESP),Health Research Institute of Navarra (IDISNA),CIBER Epidemiol & Publ Hlth CIBERESP, Madrid, Spain.;Navarra Publ Hlth Inst, Pamplona, Spain.;Navarra Inst Hlth Res IdiSNA Pamplona, Pamplona, Spain.
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- Amiano, Pilar (author)
- CIBER Epidemiology and Public Health (CIBERESP),Biodonostia Health Research Institute,CIBER Epidemiol & Publ Hlth CIBERESP, Madrid, Spain.;BioDonostia Res Inst, Publ Hlth Div Gipuzkoa, San Sebastian, Spain.
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- Memarian, Ensieh (author)
- Lund University,Lunds universitet,Allmänmedicin och klinisk epidemiologi,Forskargrupper vid Lunds universitet,Internmedicin - epidemiologi,Family Medicine and Clinical Epidemiology,Lund University Research Groups,Internal Medicine - Epidemiology,Skåne University Hospital,Lund Univ, Skane Univ Hosp, Dept Clin Sci, S-20502 Malmö, Sweden.
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- Sonestedt, Emily (author)
- Lund University,Lunds universitet,Nutritionsepidemiologi,Forskargrupper vid Lunds universitet,Nutrition Epidemiology,Lund University Research Groups,Lund Univ, Dept Clin Sci Malmö, Nutr Epidemiol, Malmö, Sweden.
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- Bueno-de-Mesquita, Bas (author)
- Imperial College London,National Institute for Public Health and the Environment (RIVM),University Medical Center Utrecht,University of Malaya,Imperial Coll London, Dept Epidemiol & Biostat, Norfolk Pl,St Marys Campus, London W2 1PG, England.;Natl Inst Publ Hlth & Environm RIVM, Dept Determinants Chron Dis DCD, POB 1, NL-3720 BA Bilthoven, Netherlands.;Univ Med Ctr, Dept Gastroenterol & Hepatol, Utrecht, Netherlands.;Univ Malaya, Fac Med, Dept Social & Prevent Med, Kuala Lumpur 50603, Malaysia.
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- May, Anne M. (author)
- University Medical Center Utrecht,Univ Utrecht, Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, STR 6-131,POB 85500, NL-3508 GA Utrecht, Netherlands.
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- Khaw, Kay-Tee (author)
- University of Cambridge,Univ Cambridge, Addenbrookes Hosp, Sch Clin Med, Cambridge CB2 2QQ, England.
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- Wareham, Nicholas J. (author)
- University of Cambridge,Univ Cambridge, Inst Metab Sci, Sch Clin Med, MRC Epidemiol Unit, Cambridge CB2 0QQ, England.
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- Tong, Tammy Y. N. (author)
- University of Oxford,Univ Oxford, Nuffield Dept Populat Hlth, Canc Epidemiol Unit, Oxford, England.
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- Huybrechts, Inge (author)
- International Agency for Research on Cancer, World Health Organization,WHO, Int Agcy Res Canc, 150 Cours Albert Thomas, F-69372 Lyon 08, France.
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- Noh, Hwayoung (author)
- International Agency for Research on Cancer, World Health Organization,WHO, Int Agcy Res Canc, 150 Cours Albert Thomas, F-69372 Lyon 08, France.
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- Aglago, Elom K. (author)
- International Agency for Research on Cancer, World Health Organization,WHO, Int Agcy Res Canc, 150 Cours Albert Thomas, F-69372 Lyon 08, France.
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- Ellingjord-Dale, Merete (author)
- Imperial College London,Imperial Coll London, Dept Epidemiol & Biostat, Norfolk Pl,St Marys Campus, London W2 1PG, England.
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Ward, Heather A. (author)
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- Aune, Dagfinn (author)
- Oslo university hospital,Imperial College London,Imperial Coll London, Dept Epidemiol & Biostat, Norfolk Pl,St Marys Campus, London W2 1PG, England.;Bjorknes Univ Coll, Dept Nutr, Oslo, Norway.;Oslo Univ Hosp, Dept Endocrinol Morbid Obes & Prevent Med, Oslo, Norway.
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- Riboli, Elio (author)
- Imperial College London,Imperial Coll London, Dept Epidemiol & Biostat, Norfolk Pl,St Marys Campus, London W2 1PG, England.
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(creator_code:org_t)
- 2020-09-03
- 2020
- English.
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In: Scientific Reports. - : Nature Publishing Group. - 2045-2322. ; 10:1
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Abstract
Subject headings
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- Abdominal and general adiposity are independently associated with mortality, but there is no consensus on how best to assess abdominal adiposity. We compared the ability of alternative waist indices to complement body mass index (BMI) when assessing all-cause mortality. We used data from 352,985 participants in the European Prospective Investigation into Cancer and Nutrition (EPIC) and Cox proportional hazards models adjusted for other risk factors. During a mean follow-up of 16.1 years, 38,178 participants died. Combining in one model BMI and a strongly correlated waist index altered the association patterns with mortality, to a predominantly negative association for BMI and a stronger positive association for the waist index, while combining BMI with the uncorrelated A Body Shape Index (ABSI) preserved the association patterns. Sex-specific cohort-wide quartiles of waist indices correlated with BMI could not separate high-risk from low-risk individuals within underweight (BMI<18.5 kg/m(2)) or obese (BMI30 kg/m(2)) categories, while the highest quartile of ABSI separated 18-39% of the individuals within each BMI category, which had 22-55% higher risk of death. In conclusion, only a waist index independent of BMI by design, such as ABSI, complements BMI and enables efficient risk stratification, which could facilitate personalisation of screening, treatment and monitoring.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
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Christakoudi, So ...
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Tsilidis, Konsta ...
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Muller, David C.
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Freisling, Heinz
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Weiderpass, Elis ...
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Overvad, Kim
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show more...
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Söderberg, Stefa ...
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Häggström, Chris ...
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Pischon, Tobias
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Dahm, Christina ...
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Zhang, Jie
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Tjonneland, Anne
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Halkjaer, Jytte
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MacDonald, Conor
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Boutron-Ruault, ...
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Mancini, Frances ...
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Kuehn, Tilman
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Kaaks, Rudolf
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Schulze, Matthia ...
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Trichopoulou, An ...
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Karakatsani, Ann ...
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Peppa, Eleni
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Masala, Giovanna
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Pala, Valeria
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Panico, Salvator ...
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Tumino, Rosario
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Sacerdote, Carlo ...
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Quiros, J. Ramon
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Agudo, Antonio
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Sanchez, Maria-J ...
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Cirera, Lluis
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Barricarte-Gurre ...
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Amiano, Pilar
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Memarian, Ensieh
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Sonestedt, Emily
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Bueno-de-Mesquit ...
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May, Anne M.
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Khaw, Kay-Tee
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Wareham, Nichola ...
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Tong, Tammy Y. N ...
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Huybrechts, Inge
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Noh, Hwayoung
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Aglago, Elom K.
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Ellingjord-Dale, ...
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Ward, Heather A.
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Aune, Dagfinn
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Riboli, Elio
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Endocrinology an ...
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MEDICAL AND HEAL ...
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Umeå University
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Uppsala University