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Greater male than f...
Greater male than female variability in regional brain structure across the lifespan
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Wierenga, Lara M. (author)
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Doucet, Gaelle E. (author)
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- Dima, Danai (author)
- Karolinska Institutet
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show more...
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- Agartz, Ingrid (author)
- Karolinska Institutet
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Aghajani, Moji (author)
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Akudjedu, Theophilus N. (author)
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Albajes-Eizagirre, Anton (author)
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Alnaes, Dag (author)
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Alpert, Kathryn, I (author)
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Andreassen, Ole A. (author)
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Anticevic, Alan (author)
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Asherson, Philip (author)
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Banaschewski, Tobias (author)
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Bargallo, Nuria (author)
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Baumeister, Sarah (author)
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Baur-Streubel, Ramona (author)
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Bertolino, Alessandro (author)
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Bonvino, Aurora (author)
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Boomsma, Dorret, I (author)
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Borgwardt, Stefan (author)
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Bourque, Josiane (author)
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den Braber, Anouk (author)
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Brandeis, Daniel (author)
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Breier, Alan (author)
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Brodaty, Henry (author)
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Brouwer, Rachel M. (author)
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Buitelaar, Jan K. (author)
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Busatto, Geraldo F. (author)
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Calhoun, Vince D. (author)
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Canales-Rodriguez, Erick J. (author)
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Cannon, Dara M. (author)
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Caseras, Xavier (author)
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Castellanos, Francisco X. (author)
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Chaim-Avancini, Tiffany M. (author)
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Ching, Christopher R. K. (author)
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Clark, Vincent P. (author)
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Conrod, Patricia J. (author)
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Conzelmann, Annette (author)
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Crivello, Fabrice (author)
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Davey, Christopher G. (author)
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Dickie, Erin W. (author)
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Ehrlich, Stefan (author)
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Van't Ent, Dennis (author)
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Fisher, Simon E. (author)
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Fouche, Jean-Paul (author)
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Franke, Barbara (author)
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Fuentes-Claramonte, Paola (author)
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- de Geus, Eco J. C. (author)
- Karolinska Institutet
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Di Giorgio, Annabella (author)
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Glahn, David C. (author)
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Gotlib, Ian H. (author)
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Grabe, Hans J. (author)
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Gruber, Oliver (author)
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Gruner, Patricia (author)
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Gur, Raquel E. (author)
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Gur, Ruben C. (author)
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Gurholt, Tiril P. (author)
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de Haan, Lieuwe (author)
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Haatveit, Beathe (author)
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Harrison, Ben J. (author)
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Hartman, Catharina A. (author)
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Hatton, Sean N. (author)
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Heslenfeld, Dirk J. (author)
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van den Heuvel, Odile A. (author)
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Hickie, Ian B. (author)
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Hoekstra, Pieter J. (author)
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Hohmann, Sarah (author)
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Holmes, Avram J. (author)
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Hoogman, Martine (author)
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Hosten, Norbert (author)
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Howells, Fleur M. (author)
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Pol, Hilleke E. Hulshoff (author)
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Huyser, Chaim (author)
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Jahanshad, Neda (author)
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James, Anthony C. (author)
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- Jiang, Jiyang (author)
- Karolinska Institutet
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Jonsson, Erik G. (author)
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Joska, John A. (author)
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Kalnin, Andrew J. (author)
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Klein, Marieke (author)
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Koenders, Laura (author)
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Kolskar, Knut K. (author)
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Kramer, Bernd (author)
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Kuntsi, Jonna (author)
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Lagopoulos, Jim (author)
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Lazaro, Luisa (author)
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Lebedeva, Irina S. (author)
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Lee, Phil H. (author)
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Lochner, Christine (author)
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Machielsen, Marise W. J. (author)
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Maingault, Sophie (author)
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Martin, Nicholas G. (author)
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Martinez-Zalacain, Ignacio (author)
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Mataix-Cols, David (author)
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Mazoyer, Bernard (author)
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McDonald, Brenna C. (author)
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McDonald, Colm (author)
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McIntosh, Andrew M. (author)
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McMahon, Katie L. (author)
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McPhilemy, Genevieve (author)
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van der Meer, Dennis (author)
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Menchon, Jose M. (author)
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Naaijen, Jilly (author)
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- Nyberg, Lars, 1966- (author)
- Umeå universitet,Diagnostisk radiologi,Institutionen för integrativ medicinsk biologi (IMB)
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Oosterlaan, Jaap (author)
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Paloyelis, Yannis (author)
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Pauli, Paul (author)
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Pergola, Giulio (author)
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Pomarol-Clotet, Edith (author)
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Portella, Maria J. (author)
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Radua, Joaquim (author)
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Reif, Andreas (author)
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Richard, Genevieve (author)
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Roffman, Joshua L. (author)
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Rosa, Pedro G. P. (author)
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Sacchet, Matthew D. (author)
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Sachdev, Perminder S. (author)
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Salvador, Raymond (author)
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Sarro, Salvador (author)
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Satterthwaite, Theodore D. (author)
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Saykin, Andrew J. (author)
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Serpa, Mauricio H. (author)
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Sim, Kang (author)
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Simmons, Andrew (author)
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Smoller, Jordan W. (author)
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Sommer, Iris E. (author)
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Soriano-Mas, Carles (author)
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Stein, Dan J. (author)
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Strike, Lachlan T. (author)
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Szeszko, Philip R. (author)
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Temmingh, Henk S. (author)
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Thomopoulos, Sophia, I (author)
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Tomyshev, Alexander S. (author)
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Trollor, Julian N. (author)
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Uhlmann, Anne (author)
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Veer, Ilya M. (author)
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Veltman, Dick J. (author)
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Voineskos, Aristotle (author)
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Volzke, Henry (author)
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Walter, Henrik (author)
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Wang, Lei (author)
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Wang, Yang (author)
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Weber, Bernd (author)
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Wen, Wei (author)
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West, John D. (author)
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Westlye, Lars T. (author)
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Whalley, Heather C. (author)
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Williams, Steven C. R. (author)
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Wittfeld, Katharina (author)
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Wolf, Daniel H. (author)
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Wright, Margaret J. (author)
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Yoncheva, Yuliya N. (author)
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Zanetti, Marcus, V (author)
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Ziegler, Georg C. (author)
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de Zubicaray, Greig, I (author)
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Thompson, Paul M. (author)
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Crone, Eveline A. (author)
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Frangou, Sophia (author)
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Tamnes, Christian K. (author)
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(creator_code:org_t)
- 2020-10-12
- 2022
- English.
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In: Human Brain Mapping. - : John Wiley & Sons. - 1065-9471 .- 1097-0193. ; 43:1, s. 470-499
- Related links:
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https://doi.org/10.1...
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https://umu.diva-por... (primary) (Raw object)
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https://onlinelibrar...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Subject headings
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- For many traits, males show greater variability than females, with possible implications for understanding sex differences in health and disease. Here, the ENIGMA (Enhancing Neuro Imaging Genetics through Meta-Analysis) Consortium presents the largest-ever mega-analysis of sex differences in variability of brain structure, based on international data spanning nine decades of life. Subcortical volumes, cortical surface area and cortical thickness were assessed in MRI data of 16,683 healthy individuals 1-90 years old (47% females). We observed significant patterns of greater male than female between-subject variance for all subcortical volumetric measures, all cortical surface area measures, and 60% of cortical thickness measures. This pattern was stable across the lifespan for 50% of the subcortical structures, 70% of the regional area measures, and nearly all regions for thickness. Our findings that these sex differences are present in childhood implicate early life genetic or gene-environment interaction mechanisms. The findings highlight the importance of individual differences within the sexes, that may underpin sex-specific vulnerability to disorders.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Radiologi och bildbehandling (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Radiology, Nuclear Medicine and Medical Imaging (hsv//eng)
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- ref (subject category)
- art (subject category)
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Wierenga, Lara M ...
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Doucet, Gaelle E ...
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Dima, Danai
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Agartz, Ingrid
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Aghajani, Moji
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Akudjedu, Theoph ...
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show more...
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Albajes-Eizagirr ...
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Alnaes, Dag
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Alpert, Kathryn, ...
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Andreassen, Ole ...
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Anticevic, Alan
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Asherson, Philip
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Banaschewski, To ...
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Bargallo, Nuria
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Baumeister, Sara ...
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Baur-Streubel, R ...
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Bertolino, Aless ...
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Bonvino, Aurora
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Boomsma, Dorret, ...
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Borgwardt, Stefa ...
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Bourque, Josiane
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den Braber, Anou ...
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Brandeis, Daniel
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Breier, Alan
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Brodaty, Henry
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Brouwer, Rachel ...
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Buitelaar, Jan K ...
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Busatto, Geraldo ...
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Calhoun, Vince D ...
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Canales-Rodrigue ...
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Cannon, Dara M.
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Caseras, Xavier
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Castellanos, Fra ...
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Chaim-Avancini, ...
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Ching, Christoph ...
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Clark, Vincent P ...
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Conrod, Patricia ...
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Conzelmann, Anne ...
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Crivello, Fabric ...
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Davey, Christoph ...
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Dickie, Erin W.
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Ehrlich, Stefan
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Van't Ent, Denni ...
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Fisher, Simon E.
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Fouche, Jean-Pau ...
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Franke, Barbara
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Fuentes-Claramon ...
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de Geus, Eco J. ...
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Di Giorgio, Anna ...
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Glahn, David C.
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Gotlib, Ian H.
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Grabe, Hans J.
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Gruber, Oliver
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Gruner, Patricia
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Gur, Raquel E.
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Gur, Ruben C.
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Gurholt, Tiril P ...
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de Haan, Lieuwe
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Haatveit, Beathe
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Harrison, Ben J.
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Hartman, Cathari ...
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Hatton, Sean N.
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Heslenfeld, Dirk ...
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van den Heuvel, ...
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Hickie, Ian B.
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Hoekstra, Pieter ...
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Hohmann, Sarah
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Holmes, Avram J.
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Hoogman, Martine
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Hosten, Norbert
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Howells, Fleur M ...
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Pol, Hilleke E. ...
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Huyser, Chaim
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Jahanshad, Neda
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James, Anthony C ...
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Jiang, Jiyang
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Jonsson, Erik G.
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Joska, John A.
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Kalnin, Andrew J ...
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Klein, Marieke
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Koenders, Laura
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Kolskar, Knut K.
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Kramer, Bernd
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Kuntsi, Jonna
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Lagopoulos, Jim
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Lazaro, Luisa
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Lebedeva, Irina ...
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Lee, Phil H.
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Lochner, Christi ...
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Machielsen, Mari ...
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Maingault, Sophi ...
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Martin, Nicholas ...
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Martinez-Zalacai ...
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Mataix-Cols, Dav ...
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Mazoyer, Bernard
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McDonald, Brenna ...
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McDonald, Colm
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McIntosh, Andrew ...
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McMahon, Katie L ...
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McPhilemy, Genev ...
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van der Meer, De ...
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Menchon, Jose M.
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Naaijen, Jilly
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Nyberg, Lars, 19 ...
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Oosterlaan, Jaap
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Paloyelis, Yanni ...
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Pauli, Paul
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Pergola, Giulio
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Pomarol-Clotet, ...
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Portella, Maria ...
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Radua, Joaquim
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Reif, Andreas
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Richard, Genevie ...
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Roffman, Joshua ...
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Rosa, Pedro G. P ...
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Sacchet, Matthew ...
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Sachdev, Permind ...
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Salvador, Raymon ...
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Sarro, Salvador
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Satterthwaite, T ...
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Saykin, Andrew J ...
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Serpa, Mauricio ...
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Sim, Kang
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Simmons, Andrew
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Smoller, Jordan ...
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Sommer, Iris E.
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Soriano-Mas, Car ...
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Stein, Dan J.
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Strike, Lachlan ...
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Szeszko, Philip ...
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Temmingh, Henk S ...
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Thomopoulos, Sop ...
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Tomyshev, Alexan ...
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Trollor, Julian ...
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Uhlmann, Anne
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Veer, Ilya M.
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Veltman, Dick J.
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Voineskos, Arist ...
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Volzke, Henry
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Walter, Henrik
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Wang, Lei
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Wang, Yang
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Weber, Bernd
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Wen, Wei
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West, John D.
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Westlye, Lars T.
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Whalley, Heather ...
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Williams, Steven ...
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Wittfeld, Kathar ...
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Wolf, Daniel H.
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Wright, Margaret ...
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Yoncheva, Yuliya ...
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Zanetti, Marcus, ...
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Ziegler, Georg C ...
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de Zubicaray, Gr ...
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Thompson, Paul M ...
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Crone, Eveline A ...
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Frangou, Sophia
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Tamnes, Christia ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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and Neurosciences
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Radiology Nuclea ...
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Human Brain Mapp ...
- By the university
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Umeå University
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Karolinska Institutet