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  • Fridberg, MarieLund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Institutionen för translationell medicin,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine,Department of Translational Medicine (author)

Immunohistochemical analyses of phosphatases in childhood B-cell lymphoma : lower expression of PTEN and HePTP and higher number of positive cells for nuclear SHP2 in B-cell lymphoma cases compared to controls

  • Article/chapterEnglish2008

Publisher, publication year, extent ...

  • 2009-07-09
  • Taylor & Francis,2008
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:umu-177650
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-177650URI
  • https://doi.org/10.1080/08880010802237054DOI
  • https://lup.lub.lu.se/record/1222880URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-5160URI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Although many pediatric B-cell lymphoma patients are being cured today, much is still unknown about the pathogenesis of this disease. Protein tyrosine phosphatases are involved in the control of survival, growth, and differentiation of cells. The authors have analyzed 26 pediatric B-cell lymphoma cases for the expression of a panel of phosphatases and report a statistically significant lower expression intensity of PTEN and HePTP and higher nuclear SHP2 expression in B-cell lymphoma cases compared to lymphoid tissue. Knowledge about the expression of key regulatory proteins in pediatric B-cell lymphomas is necessary for revealing the complex molecular background of this disease.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Kjellström, Sofia (author)
  • Anagnostaki, Lola (author)
  • Skogvall, Ingela (author)
  • Mustelin, Tomas (author)
  • Wiebe, ThomasLund University,Lunds universitet,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Section V,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)pedi-twi (author)
  • Persson, Jenny L.,ProfessorLund University,Lunds universitet,Experimentell cancerforskning, Malmö,Forskargrupper vid Lunds universitet,Experimental Cancer Research, Malmö,Lund University Research Groups(Swepub:lu)medk-jpe (author)
  • Dictor, MichaelLund University,Lunds universitet,Tumörmikromiljö,Sektion I,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Tumor microenvironment,Section I,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)pat-mdi (author)
  • Gjörloff Wingren, AnetteMalmö högskola,Lund University,Lunds universitet,Institutionen för translationell medicin,Medicinska fakulteten,Department of Translational Medicine,Faculty of Medicine,Fakulteten för hälsa och samhälle (HS)(Swepub:mau)hsangj (author)
  • TumörmikromiljöSektion I (creator_code:org_t)

Related titles

  • In:Pediatric Hematology & Oncology: Taylor & Francis25, s. 528-5400888-00181521-0669
  • In:Pediatr Hematol Oncol: Taylor & Francis25, s. 528-540

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