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Symptoms and management of cow's milk allergy : perception and evidence

Robert, E. (författare)
UZ Brussel, KidZ Health Castle, Vrije Universiteit Brussel (VUB), Brussels, Belgium
Al-Hashmi, H.A. (författare)
Pediatric Department, King Abdulaziz Hospital, Jeddah, Saudi Arabia
Al-Mehaidib, A. (författare)
Department of Pediatrics, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia
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Alsarraf, K. (författare)
Department of Pediatric Gastroenterology and Hepatology, Al Amiri Hospital (MOH), Kuwait City, Kuwait; Department of Pediatric Gastroenterology and Hepatology, Dar Al Shefaa Hospital (PVT), Hawally, Kuwait
Al-Turaiki, M. (författare)
Department of Pediatrics, King Salman Hospital, Riyadh, Saudi Arabia
Aldekhail, W. (författare)
Section of Gastroenterology and Hepatology, Department of Pediatrics, King Faisal Specialist Hospital and 12 Research Centre, Riyadh, Saudi Arabia
Al-Herz, W. (författare)
Department of Pediatrics, College of Medicine, Kuwait University, Kuwait City, Kuwait
Alkhabaz, A. (författare)
Department of Pediatrics, Allergist & Clinical Immunology, Mubarak AlKabeer Hospital, Jabriya, Kuwait
Bawakid, Khalid O. (författare)
Department of Pediatrics, MCH Hospital Jeddah, Jeddah, Saudi Arabia
Elghoudi, A. (författare)
Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates; CMHS, UAE University, Abu Dhabi, United Arab Emirates
El Hodhod, M. (författare)
Faculty of Medicine, Ain Shams University, Cairo, Egypt
Hussain, Ali A. (författare)
Department of Pediatrics, Al Adan and Al Salam International Hospitals, Kuwait City, Kuwait
Kamal, Naglaa M. (författare)
Department of Pediatrics & Pediatric Hepatology, Kasr Alainy Faculty of Medicine, Cairo University, Cairo, Egypt
Goronfolah, L.T. (författare)
College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia
Nasrallah, B. (författare)
Department of Pediatrics, American Hospital Dubai, Dubai, United Arab Emirates
Sengupta, K. (författare)
Department of Pediatrics, NMC Specialty Hospital, Dubai, United Arab Emirates
Broekaert, I. (författare)
Department of Pediatrics, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany
Domellöf, Magnus, 1963- (författare)
Umeå universitet,Pediatrik
Indrio, F. (författare)
Department of Pediatric, University of Salento, Lecce, Italy
Lapillonne, A. (författare)
Neonatal Intensive Care Unit, Necker-EnfantsMalades Hospital, Paris University, Paris, France; CNRC, Department of Pediatrics, Baylor College of Medicine, TX, Houston, United States
Pienar, C. (författare)
Department of Pediatrics, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania
Ribes-Koninckx, C. (författare)
Coeliac Disease and Gastrointestinal Immunopathology Research Unit, Hospital La Fe Research Institute Valencia, Valencia, Spain
Shamir, R. (författare)
Institute of Gastroenterology, Nutrition and Liver Diseases, Schneider Children’s Medical Center, Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel
Szajewska, H. (författare)
Department of Pediatrics, The Medical University of Warsaw, Warsaw, Poland
Thapar, N. (författare)
Department of Gastroenterology, Hepatology and Liver Transplant, Queensland Children's Hospital, QLD, Brisbane, Australia; School of Medicine, University of Queensland, QLD, Brisbane, Australia; Woolworths Centre for Child Nutrition Research, Queensland University of Technology, QLD, Brisbane, Australia; Department of Pediatrics, UCL Great Ormond Street Institute of Child Health, London, United Kingdom
Thomassen, R.A. (författare)
Division of Pediatric and Adolescent Medicine, Department of Pediatric Medicine, Oslo University Hospital, Oslo, Norway
Verduci, E. (författare)
Department of Pediatrics, Vittore Buzzi Children's Hospital University of Milan, Milan, Italy
West, Christina E. (författare)
Umeå universitet,Pediatrik
Vandenplas, Y. (författare)
UZ Brussel, KidZ Health Castle, Vrije Universiteit Brussel (VUB), Brussels, Belgium
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 (creator_code:org_t)
Frontiers Media S.A. 2024
2024
Engelska.
Ingår i: Frontiers in Allergy. - : Frontiers Media S.A.. - 2673-6101. ; 5
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • Introduction: The diagnosis and management of cow's milk allergy (CMA) is a topic of debate and controversy. Our aim was to compare the opinions of expert groups from the Middle East (n = 14) and the European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) (n = 13).Methods: These Expert groups voted on statements that were developed by the ESPGHAN group and published in a recent position paper. The voting outcome was compared.Results: Overall, there was consensus amongst both groups of experts. Experts agreed that symptoms of crying, irritability and colic, as single manifestation, are not suggestive of CMA. They agreed that amino-acid based formula (AAF) should be reserved for severe cases (e.g., malnutrition and anaphylaxis) and that there is insufficient evidence to recommend a step-down approach. There was no unanimous consensus on the statement that a cow's milk based extensively hydrolysed formula (eHF) should be the first choice as a diagnostic elimination diet in mild/moderate cases. Although the statements regarding the role for hydrolysed rice formula as a diagnostic and therapeutic elimination diet were accepted, 3/27 disagreed. The votes regarding soy formula highlight the differences in opinion in the role of soy protein in CMA dietary treatment. Generally, soy-based formula is seldom available in the Middle-East region. All ESPGHAN experts agreed that there is insufficient evidence that the addition of probiotics, prebiotics and synbiotics increase the efficacy of elimination diets regarding CMA symptoms (despite other benefits such as decrease of infections and antibiotic intake), whereas 3/14 of the Middle East group thought there was sufficient evidence.Discussion: Differences in voting are related to geographical, cultural and other conditions, such as cost and availability. This emphasizes the need to develop region-specific guidelines considering social and cultural conditions, and to perform further research in this area.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Gastroenterologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Pediatrik (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Pediatrics (hsv//eng)

Nyckelord

amino acid formula
cow's milk allergy
extensively hydrolysed formula
hydrolysed rice formula
prebiotic
probiotic
soy formula
synbiotic

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