Sökning: WFRF:(Walther Sten M. 1954 )
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COVID-19 critical i...
COVID-19 critical illness in Sweden : characteristics and outcomes at a national population level
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- Mårtensson, Johan (författare)
- Karolinska Institutet
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- Engerström, Lars (författare)
- Linköpings universitet,Institutionen för hälsa, medicin och vård,Medicinska fakulteten,Region Östergötland, Thorax-kärlkliniken i Östergötland,Region Östergötland, Anestesi- och intensivvårdskliniken VIN,Swedish Intens Care Registry, Karlstad, Sweden
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- Walther, Sten M., 1954- (författare)
- Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Thorax-kärlkliniken i Östergötland,Region Östergötland, Anestesi- och intensivvårdskliniken VIN,Swedish Intens Care Registry, Sweden
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- Grip, Jonathan (författare)
- Karolinska Institutet
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- Berggren, Ritva Kiiski (författare)
- Department of Anesthesia, Intensive Care and Perioperative Services, Umeå University Hospital, Umeå, Sweden,Swedish Intens Care Registry, Sweden; Umea Univ Hosp, Sweden
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- Larsson, Emma (författare)
- Karolinska Institutet
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(creator_code:org_t)
- Strawberry Hills, NSW, Australia : AUSTRALASIAN MED PUBL CO LTD, 2020
- 2020
- Engelska.
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Ingår i: Critical Care and Resuscitation. - Strawberry Hills, NSW, Australia : AUSTRALASIAN MED PUBL CO LTD. - 1441-2772. ; 22:4, s. 312-320
- Relaterad länk:
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https://ccr.cicm.org...
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https://urn.kb.se/re...
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https://doi.org/10.5...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Ämnesord
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- Objective: During the coronavirus disease 2019 (COVID-19) pandemic, baseline demographics and comorbidities of patients with COVID-19 have been presented, but there are limited data on outcomes of severely ill patients. We aimed to examine the association between patient characteristics and 30-day mortality among patients with COVID-19 treated in the intensive care unit (ICU).Design: Population-based cohort study.Setting: ICUs in Sweden.Participants: All consecutive patients with COVID-19 admitted to Swedish ICUs from 6 March to 5 April 2020.Main outcome measures: The primary outcome was 30-day mortality after ICU admission. Patient demographics, comorbidities and clinical characteristics were also retrieved.Results: A total of 604 patients were included. The median age was 61 years (interquartile range [IQR], 52-70 years) and 458 patients (76%) were males. The most common comorbidities were hypertension (35.9%) and diabetes (25.7%), whereas 36.4% of patients had no comorbidities. Median Simplified Acute Physiology Score (SAPS) 3 was 53 (IQR, 46-60). Of 573 patients with available respiratory support data, 487 (85.0%) received invasive mechanical ventilation. Among 518 patients with available data, 117 (22.6%) received renal replacement therapy. Median length of stay was 13 days (IQR, 6-20 days). Mortality at 30 days was 32.6%. In the multivariable Cox regression model, age (hazard ratio [HR] 1.06; 95% CI, 1.04-1.07 per year), the presence of one or more comorbidities (HR, 1.80; 95% CI, 1.20-2.68), chronic obstructive pulmonary disease or asthma (HR, 1.68; 95% CI, 1.12-2.50), hypertension (HR, 1.41; 95% CI, 1.01-1.99), and acute illness severity (SAPS 3 excluding age and comorbidity) (HR, 1.06; 95% CI, 1.04-1.09) were associated with 30-day mortality.Conclusions: This population-based cohort study presents 30-day mortality of 604 ICU patients with COVID-19. The higher mortality was explained by older age, the presence chronic illness, and acute illness severity.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Anestesi och intensivvård (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Anesthesiology and Intensive Care (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinsk bioteknologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Medical Biotechnology (hsv//eng)
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