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Alcohol consumption...
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Csengeri, DoraDepartment of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany
(författare)
Alcohol consumption, cardiac biomarkers, and risk of atrial fibrillation and adverse outcomes
- Artikel/kapitelEngelska2021
Förlag, utgivningsår, omfång ...
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2021-01-13
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Oxford University Press,2021
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electronicrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:umu-181998
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-181998URI
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https://doi.org/10.1093/eurheartj/ehaa953DOI
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Språk:engelska
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Sammanfattning på:engelska
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Klassifikation
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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AIMS: There is inconsistent evidence on the relation of alcohol intake with incident atrial fibrillation (AF), in particular at lower doses. We assessed the association between alcohol consumption, biomarkers, and incident AF across the spectrum of alcohol intake in European cohorts.METHODS AND RESULTS: In a community-based pooled cohort, we followed 107 845 individuals for the association between alcohol consumption, including types of alcohol and drinking patterns, and incident AF. We collected information on classical cardiovascular risk factors and incident heart failure (HF) and measured the biomarkers N-terminal pro-B-type natriuretic peptide and high-sensitivity troponin I. The median age of individuals was 47.8 years, 48.3% were men. The median alcohol consumption was 3 g/day. N = 5854 individuals developed AF (median follow-up time: 13.9 years). In a sex- and cohort-stratified Cox regression analysis alcohol consumption was non-linearly and positively associated with incident AF. The hazard ratio for one drink (12 g) per day was 1.16, 95% CI 1.11-1.22, P < 0.001. Associations were similar across types of alcohol. In contrast, alcohol consumption at lower doses was associated with reduced risk of incident HF. The association between alcohol consumption and incident AF was neither fully explained by cardiac biomarker concentrations nor by the occurrence of HF.CONCLUSIONS: In contrast to other cardiovascular diseases such as HF, even modest habitual alcohol intake of 1.2 drinks/day was associated with an increased risk of AF, which needs to be considered in AF prevention.
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Biuppslag (personer, institutioner, konferenser, titlar ...)
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Sprünker, Ngoc-AnhDepartment of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany
(författare)
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Niiranen, TeemuDivision of Medicine, Turku University Hospital and University of Turku, Turku, Finland; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland
(författare)
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Vishram-Nielsen, Julie Kk.Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Capital Region of Denmark, Frederiksberg, Denmark; Department of Cardiology, Righospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
(författare)
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Costanzo, SimonaDepartment of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Italy
(författare)
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Söderberg, StefanUmeå universitet,Avdelningen för medicin(Swepub:umu)stso0001
(författare)
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Jensen, Steen M.Umeå universitet,Avdelningen för medicin(Swepub:umu)stje0001
(författare)
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Vartiainen, ErkkiDepartment of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland
(författare)
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Donati, Maria BenedettaDepartment of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Italy
(författare)
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Magnussen, ChristinaDepartment of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany; German Centre for Cardiovascular Research (DZHK), Berlin, Germany
(författare)
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Camen, StephanDepartment of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany; German Centre for Cardiovascular Research (DZHK), Berlin, Germany
(författare)
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Gianfagna, FrancescoResearch Center in Epidemiology and Preventive Medicine (EPIMED), Department of Medicine and Surgery, University of Insubria, Varese, Italy
(författare)
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Løchen, Maja-LisaDepartment of Community Medicine, UiT The Arctic University of Norway, Norway
(författare)
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Kee, FrankCenter for Public Health, Institute of Clinical Sciences A, Queens University, Belfast, Ireland
(författare)
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Kontto, JukkaDepartment of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland
(författare)
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Mathiesen, Ellisiv B.Brain and Circulation Research Group, Department of Clinical Medicine, UiT The Arctic University of Norway, Norway
(författare)
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Koenig, WolfgangDeutsches Herzzentrum München, Munich, Germany; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany; Institute of Epidemiology and Medial Biometry, University of Ulm, Ulm, Germany
(författare)
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Stefan, BlankenbergDepartment of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany; German Centre for Cardiovascular Research (DZHK), Berlin, Germany
(författare)
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de Gaetano, GiovanniDepartment of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Italy
(författare)
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Jørgensen, TorbenCenter for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Capital Region of Denmark, Frederiksberg, Denmark; Department of Public Health, Faculty of Health and Medical Science, University of Copenhagen, Copenhagen, Denmark; Faculty of Medicine, Aalborg University, Aalborg, Denmark
(författare)
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Kuulasmaa, KariDepartment of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland
(författare)
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Zeller, TanjaDepartment of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany
(författare)
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Salomaa, VeikkoDepartment of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland
(författare)
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Iacoviello, LiciaDepartment of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Italy; Research Center in Epidemiology and Preventive Medicine (EPIMED), Department of Medicine and Surgery, University of Insubria, Varese, Italy
(författare)
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Schnabel, Renate B.Department of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, Germany; German Centre for Cardiovascular Research (DZHK), Berlin, Germany
(författare)
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Department of Cardiology, University Heart & Vascular Center Hamburg, Hamburg, GermanyDivision of Medicine, Turku University Hospital and University of Turku, Turku, Finland; Department of Public Health Solutions, Finnish Institute for Health and Welfare, Helsinki, Finland
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:European Heart Journal: Oxford University Press42:12, s. 1170-11770195-668X1522-9645
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- Av författaren/redakt...
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Csengeri, Dora
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Sprünker, Ngoc-A ...
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Niiranen, Teemu
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Vishram-Nielsen, ...
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Costanzo, Simona
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Söderberg, Stefa ...
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visa fler...
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Jensen, Steen M.
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Vartiainen, Erkk ...
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Donati, Maria Be ...
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Magnussen, Chris ...
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Camen, Stephan
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Gianfagna, Franc ...
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Løchen, Maja-Lis ...
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Kee, Frank
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Kontto, Jukka
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Mathiesen, Ellis ...
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Koenig, Wolfgang
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Stefan, Blankenb ...
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de Gaetano, Giov ...
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Jørgensen, Torbe ...
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Kuulasmaa, Kari
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Zeller, Tanja
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Salomaa, Veikko
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Iacoviello, Lici ...
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Schnabel, Renate ...
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