Higher risk of type 2 diabetes in women with hyperandrogenic polycystic ovary syndrome

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Sökning: WFRF:(Turkmen Sahruh) > (2020-2023) > Higher risk of type...

Persson, SofiaUppsala universitet,Reproduktiv hälsa,Sundsvall Cty Hosp, Dept Obstet & Gynecol, Sundsvall, Sweden. (författare)

Higher risk of type 2 diabetes in women with hyperandrogenic polycystic ovary syndrome

Artikel/kapitelEngelska2021

Förlag, utgivningsår, omfång ...

Elsevier,2021
electronicrdacarrier

Nummerbeteckningar

LIBRIS-ID:oai:DiVA.org:umu-184050
https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-184050URI
https://doi.org/10.1016/j.fertnstert.2021.04.018DOI
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-457442URI

Kompletterande språkuppgifter

Språk:engelska
Sammanfattning på:engelska

Ingår i deldatabas

SwePubSwePub

Klassifikation

Ämneskategori:ref swepub-contenttype
Ämneskategori:art swepub-publicationtype

Anmärkningar

Objective: To assess the risk of type 2 diabetes (T2D) in women with polycystic ovary syndrome (PCOS) in relation to body mass index (BMI) and the hyperandrogenic (HA) PCOS phenotype.Design: Population-based cohort study.Setting: Data from six Swedish national registers, with participants being followed for a maximum of 19 years.Patient(s): All women with an International Statistical Classification of Diseases and Related Health Problems, version 10, diagnosis of PCOS, androgen excess, or anovulatory infertility born between 1950 and 1999 (n = 52,535) were identified in the Patient Register. The HA PCOS phenotype was defined by two filled prescriptions for anti-androgenic drugs. For each woman with PCOS, five control women (n = 254,624) were randomly chosen from the Total Population Register, matched for age and geographic area.Intervention(s): No interventions were performed.Main Outcome Measure(s): International Statistical Classification of Diseases and Related Health Problems, version 10, diagnosis of T2D or prescription of antidiabetic treatment other than metformin.Result(s): The cumulative incidence rates of T2D were 1.3%, 4.4%, and 14.2% in controls (non-PCOS women) and women with normoandrogenic (NA) and HA PCOS, respectively. After adjustment for BMI, women with PCOS had a twofold higher rate of T2D than non-PCOS women (adjusted hazard ratio, 2.52 [95% confidence interval, 2.15–2.96]). Women with HA PCOS had a higher rate of T2D than those with NA PCOS (adjusted hazard ratio, 3.86 [95% confidence interval, 3.16–4.72]).Conclusion(s): Polycystic ovary syndrome is an independent risk factor for T2D, even after adjustment for BMI. Women with the HA PCOS phenotype face an even higher risk of T2D than those with the NA PCOS phenotype.

Ämnesord och genrebeteckningar

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Reproduktionsmedicin och gynekologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Obstetrics, Gynaecology and Reproductive Medicine hsv//eng
diabetes
hyperandrogenism
PCOS
polycystic ovary syndrome
type 2 diabetes

Biuppslag (personer, institutioner, konferenser, titlar ...)

Elenis, Evangelia,1983-Uppsala universitet,Reproduktiv hälsa(Swepub:uu)evael941 (författare)
Turkmen, SahruhUmeå universitet,Obstetrik och gynekologi,Department of Obstetrics and Gynecology, Sundsvall County Hospital, Sundsvall, Sweden,Umeå Univ, Dept Clin Sci Obstet & Gynecol, Sundsvall Res Unit, Umeå, Sweden.;Sundsvall Cty Hosp, Dept Obstet & Gynecol, Sundsvall, Sweden.(Swepub:umu)satu0001 (författare)
Kramer, Michael S.Departments of Epidemiology, Biostatistics and Occupational Health and of Pediatrics, McGill University Faculty of Medicine, QC, Montreal, Canada; Department of Obstetrics and Gynaecology, National University Hospital, National University of Singapore, Singapore,McGill Univ, Fac Med, Dept Epidemiol, Montreal, PQ, Canada.;McGill Univ, Fac Med, Dept Biostat & Occupat Hlth, Montreal, PQ, Canada.;McGill Univ, Fac Med, Dept Pediat, Montreal, PQ, Canada.;Natl Univ Singapore, Natl Univ Hosp, Dept Obstet & Gynaecol, Singapore, Singapore. (författare)
Yong, Eu-LeongDepartment of Obstetrics and Gynaecology, National University Hospital, National University of Singapore, Singapore,Natl Univ Singapore, Natl Univ Hosp, Dept Obstet & Gynaecol, Singapore, Singapore. (författare)
Sundström Poromaa, Inger,1964-Uppsala universitet,Reproduktiv hälsa(Swepub:uu)inspo702 (författare)
Uppsala universitetReproduktiv hälsa (creator_code:org_t)

Sammanhörande titlar

Ingår i:Fertility and Sterility: Elsevier116:3, s. 862-8710015-02821556-5653

Internetlänk

Hitta via bibliotek

Fertility and Sterility (Sök värdpublikationen i LIBRIS)

Till lärosätets databas

Hitta mer i SwePub

Av författaren/redakt...: Persson, Sofia; Elenis, Evangeli ...; Turkmen, Sahruh; Kramer, Michael ...; Yong, Eu-Leong; Sundström Poroma ...

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Reproduktionsmed ...

Artiklar i publikationen: Fertility and St ...

Av lärosätet: Umeå universitet; Uppsala universitet

Sök utanför SwePub

Sök vidare i:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se