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Analysis of extraco...
Analysis of extracorporeal photopheresis within the frame of the WAA register
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- Blaha, M. (författare)
- Faculty Nemocnice Hradec Kralove, University Hospital Hradec Kralove, Hradec Králové, Czech Republic,Univ Hosp Hradec Kralove, Fac Nemocnice Hradec Kralove, Hradec Kralove, Czech Republic.
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- Gasova, Z. (författare)
- Institute of Hematology and Blood Transfusion, UHKT, Prague, Czech Republic
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- Berlin, Gösta (författare)
- Linköping University,Linköpings universitet,Avdelningen för inflammation och infektion,Medicinska fakulteten,Region Östergötland, Klinisk immunologi och transfusionsmedicin,Linköping Univ, Dept Clin Immunol & Transfus Med, Linköping, Sweden.
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- Audzijoniene, J. (författare)
- Hematology, onkology and Transfusion Centre, University Hospital, Vilnius, Lithuania,Linköping Univ, Dept Biomed Clin Sci, Linköping, Sweden.;Univ Hosp, Hematol Onkol & Transfus Ctr, Vilnius, Lithuania.
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- Griskevicius, A. (författare)
- Hematology, onkology and Transfusion Centre, University Hospital, Vilnius, Lithuania,Univ Hosp, Hematol Onkol & Transfus Ctr, Vilnius, Lithuania.
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- Dykes, J. (författare)
- Lund University,Lunds universitet,Avdelningen för hematologi och transfusionsmedicin,Institutionen för laboratoriemedicin,Medicinska fakulteten,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Division of Hematology and Transfusion Medicine,Department of Laboratory Medicine,Faculty of Medicine,LUCC: Lund University Cancer Centre,Other Strong Research Environments
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- Bhuiyanova, Z. (författare)
- Institute of Hematology and Blood Transfusion, UHKT, Prague, Czech Republic,UHKT, Inst Hematol & Blood Transfus, Prague, Czech Republic.
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- Lanska, M. (författare)
- Faculty Nemocnice Hradec Kralove, University Hospital Hradec Kralove, Hradec Králové, Czech Republic,Univ Hosp Hradec Kralove, Fac Nemocnice Hradec Kralove, Hradec Kralove, Czech Republic.
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- Eich, Torsten, 1972- (författare)
- Uppsala universitet,Klinisk immunologi,Uppsala Akad Univ Hosp, Uppsala, Sweden,Uppsala University Hospital
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- Vrielink, H. (författare)
- Sanquin Blood Supply, Amsterdam, Netherlands.
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- Witt, V. (författare)
- Apheresis Centres, St. Anna Kinderspital/MUW, Vienna, Austria,St. Anna Children's Hospital
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- Seval, G.C. (författare)
- Hematology, Ankara University School of Medicine, Ankara, Turkey,Ankara Univ, Sch Med, Hematol, Ankara, Turkey.
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- Ilhan, O. (författare)
- Hematology, Ankara University School of Medicine, Ankara, Turkey,Ankara Univ, Sch Med, Hematol, Ankara, Turkey.
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- Stegmayr, Bernd, 1949- (författare)
- Umeå University,Umeå universitet,Avdelningen för medicin,Umeå Univ, Dept Publ Hlth & Clin Med, Umeå, Sweden.
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Faculty Nemocnice Hradec Kralove, University Hospital Hradec Kralove, Hradec Králové, Czech Republic Univ Hosp Hradec Kralove, Fac Nemocnice Hradec Kralove, Hradec Kralove, Czech Republic (creator_code:org_t)
- Elsevier, 2021
- 2021
- Engelska.
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Ingår i: Transfusion and apheresis science. - : Elsevier. - 1473-0502 .- 1878-1683. ; 60:5
- Relaterad länk:
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https://doi.org/10.1...
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https://umu.diva-por... (primary) (Raw object)
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http://www.trasci.co...
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https://liu.diva-por... (primary) (Raw object)
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https://uu.diva-port... (primary) (Raw object)
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http://dx.doi.org/10... (free)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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https://lup.lub.lu.s...
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Abstract
Ämnesord
Stäng
- The aim of the study was to investigate safety and if extracorporeal photopheresis (ECP) may change health criteria (HC) and quality of life (QoL).Material and method: 560 patients (33 % women) were treated with ECP for a total of 13,871 procedures during a 17-years period. Mean age was 48 years (±18, range 3−81 years). Self-estimation of QoL was graded: 0 (suicidal) up to 10 (best ever) and HC: 0 (Bed ridden, ICU condition) up to 10 (athletic). Adverse events were analyzed. ANOVA and paired comparisons were performed.Results: Patients were treated due to graft versus host disease (GVHD, n = 317), skin lymphoma (n = 70), solid organ transplants (n = 47), skin diseases (n = 20) and other diseases (n = 106). Adverse events (AEs) were registered in 5.4 % of the first treatments and in 1.2 % of the subsequent procedures. Severe AEs were present in 0.04 % of all procedures. No patient died due to the procedure. Tingling and stitching were the most common AE. For those with GVHD an improvement was noticed within approximately 10 procedures of ECP in the severity stage, QoL (from a mean of 6.1 to 6.8, p < 0.002) and the HC (6.1 -> 6.4, p < 0.014) and improved further with added procedures.Conclusion: Photopheresis is an established therapy with few side effects. The present study of soft variables indicate that GVHD shows benefits upon ECP within approximately 10 procedures in regard to the severity of mainly skin GVHD, and lower baseline levels of HC and QoL.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Hematologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Hematology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Nyckelord
- Adverse events
- Apheresis
- Extracorporeal photopheresis
- Graft versus host disease
- Health criteria
- Quality of life
- Adverse events
- Apheresis
- Extracorporeal photopheresis
- Graft versus host disease
- Health criteria
- Quality of life
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
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Blaha, M.
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Gasova, Z.
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Berlin, Gösta
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Audzijoniene, J.
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Griskevicius, A.
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Dykes, J.
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visa fler...
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Bhuiyanova, Z.
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Lanska, M.
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Eich, Torsten, 1 ...
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Vrielink, H.
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Witt, V.
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Seval, G.C.
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Ilhan, O.
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Stegmayr, Bernd, ...
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Hematologi
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kirurgi
- Artiklar i publikationen
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Transfusion and ...
- Av lärosätet
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Umeå universitet
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Linköpings universitet
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Uppsala universitet
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Lunds universitet