SwePub
Sök i LIBRIS databas

  Extended search

WFRF:(Ward Eric J.)
 

Search: WFRF:(Ward Eric J.) > Socioeconomic Effec...

  • Cirera, LluísUniversity of Murcia (author)

Socioeconomic Effect of Education on Pancreatic Cancer Risk in Western Europe : An Update on the EPIC Cohorts Study

  • Article/chapterEnglish2019

Publisher, publication year, extent ...

  • American Association for Cancer Research (AACR),2019
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:umu-184274
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-184274URI
  • https://doi.org/10.1158/1055-9965.EPI-18-1153DOI
  • https://lup.lub.lu.se/record/d2d328b8-43e7-4d5c-9861-0e28618e1e8aURI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:141609140URI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • BACKGROUND: To analyze the potential effect of social inequality on pancreatic cancer risk in Western Europe, by reassessing the association within the European Prospective Investigation into Cancer and Nutrition (EPIC) Study, including a larger number of cases and an extended follow-up.METHODS: Data on highest education attained were gathered for 459,170 participants (70% women) from 10 European countries. A relative index of inequality (RII) based on adult education was calculated for comparability across countries and generations. Cox regression models were applied to estimate relative inequality in pancreatic cancer risk, stratifying by age, gender, and center, and adjusting for known pancreatic cancer risk factors.RESULTS: A total of 1,223 incident pancreatic cancer cases were included after a mean follow-up of 13.9 (±4.0) years. An inverse social trend was found in models adjusted for age, sex, and center for both sexes [HR of RII, 1.27; 95% confidence interval (CI), 1.02-1.59], which was also significant among women (HR, 1.42; 95% CI, 1.05-1.92). Further adjusting by smoking intensity, alcohol consumption, body mass index, prevalent diabetes, and physical activity led to an attenuation of the RII risk and loss of statistical significance.CONCLUSIONS: The present reanalysis does not sustain the existence of an independent social inequality influence on pancreatic cancer risk in Western European women and men, using an index based on adult education, the most relevant social indicator linked to individual lifestyles, in a context of very low pancreatic cancer survival from (quasi) universal public health systems.IMPACT: The results do not support an association between education and risk of pancreatic cancer.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Huerta, José MaríaMurcia Regional Health Council (author)
  • Chirlaque, María DoloresMurcia Regional Health Council (author)
  • Overvad, KimAarhus University (author)
  • Lindström, MartinLund University,Lunds universitet,Socialmedicin och hälsopolitik,Forskargrupper vid Lunds universitet,Social Medicine and Health Policy,Lund University Research Groups(Swepub:lu)ekh-ml0 (author)
  • Regnér, SaraLund University,Lunds universitet,Socialmedicin och hälsopolitik,Forskargrupper vid Lunds universitet,Social Medicine and Health Policy,Lund University Research Groups(Swepub:lu)kir-sre (author)
  • Tjønneland, AnneUniversity of Copenhagen (author)
  • Boutron-Ruault, Marie-ChristineStabilite genetique et oncogenese (author)
  • Rebours, VincianeBeaujon Hospital (author)
  • Fagherazzi, GuyStabilite genetique et oncogenese (author)
  • Katzke, Verena A.German Cancer Research Centre (author)
  • Boeing, HeinerGerman Institute of Human Nutrition (author)
  • Peppa, EleniNational and Kapodistrian University of Athens (author)
  • Trichopoulou, AntoniaNational and Kapodistrian University of Athens (author)
  • Valanou, ElissavetNational and Kapodistrian University of Athens (author)
  • Palli, Domenico (author)
  • Grioni, Sara (author)
  • Panico, Salvatore (author)
  • Tumino, Rosario (author)
  • Ricceri, Fulvio (author)
  • van Gils, CarlaUniversity Medical Center Utrecht (author)
  • Vermeulen, Roel C. H. (author)
  • Skeie, Guri (author)
  • Braaten, Tonje (author)
  • Weiderpass, ElisabeteKarolinska Institutet (author)
  • Merino, Susana (author)
  • Sánchez, María José (author)
  • Larrañaga, Nerea (author)
  • Ardanaz, Eva (author)
  • Sund, MalinDepartment of Public Health, Aarhus University, Aarhus, Denmark(Swepub:umu)masu0021 (author)
  • Khaw, Kay-Tee (author)
  • Key, Timothy J. (author)
  • Jenab, Mazda (author)
  • Naudin, Sabine (author)
  • Murphy, Neil (author)
  • Aune, Dagfinn (author)
  • Ward, Heather (author)
  • Riboli, Elio (author)
  • Bueno-de-Mesquita, Bas (author)
  • Navarro, Carmen (author)
  • Duell, Eric J.Catalan Institute of Oncology (author)
  • University of MurciaMurcia Regional Health Council (creator_code:org_t)

Related titles

  • In:Cancer Epidemiology, Biomarkers and Prevention: American Association for Cancer Research (AACR)28:6, s. 1089-10921055-99651538-7755

Internet link

Find in a library

To the university's database

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view