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Sökning: WFRF:(Sahlin Carin) > (2005-2009) > Obstructive sleep a...

  • Sahlin, Carin,1953-Umeå universitet,Lungmedicin (författare)

Obstructive sleep apnea is a risk factor for death in patients with stroke : a 10-year follow-up

  • Artikel/kapitelEngelska2008

Förlag, utgivningsår, omfång ...

  • Chicago :American medical association,2008
  • printrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:umu-18814
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-18814URI
  • https://doi.org/10.1001/archinternmed.2007.70DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:116547019URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  •  Background: Sleep apnea occurs frequently among stroke patients, but it is still unknown whether a diagnosis of sleep apnea is an independent risk factor for mortality. We aimed to investigate whether obstructive or central sleep apnea was related to a reduced long-term survival among stroke patients.Methods: One hundred and thirty-two of 151 patients admitted for in-hospital stroke rehabilitation in the catchment area of Umeå from 1 April 1995 to 1 May 1997 underwent overnight sleep apnea recordings at 23 ± 8 days after onset of stroke. All patients were followed-up prospectively for a mean (SD) of 10.0 ± 0.6 years, with death as the primary outcome and no one was lost to follow-up. Obstructive sleep apnea was defined when the obstructive apnea-hypopnea index was over 15 and central sleep apnea when the central apnea-hypopnea index was over 15. Patients with an obstructive and a central apnea-hypopnea index below 15 served as controls.Results: Of 132 enrolled patients, 116 had died at follow-up. The risk of death was higher among the 23 patients with obstructive sleep apnea than controls (adjusted hazard ratio, 1.76; 95% confidence interval 1.05 to 2.95, p=0.03), independent of age, gender, body-mass index, smoking, hypertension, diabetes mellitus, atrial fibrillation, mini-mental state examination and Barthel activity of daily living There was no difference in mortality between the 28 patients with central sleep apnea and controls (adjusted hazard ratio, 1.07; 95 percent confidence interval 0.65 to 1.76, p=0.053).Conclusions: Stroke patients with obstructive sleep apnea run an increased risk of early death. Central sleep apnea was not related to early death among the present patients.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Sandberg, OlovUmeå universitet,Geriatrik (författare)
  • Gustafson, YngveUmeå universitet,Geriatrik(Swepub:umu)yngu0001 (författare)
  • Bucht, GöstaUmeå universitet,Geriatrik(Swepub:umu)gubu0001 (författare)
  • Carlberg, BoUmeå universitet,Medicin(Swepub:umu)boca0001 (författare)
  • Stenlund, HansUmeå universitet,Epidemiologi och folkhälsovetenskap(Swepub:umu)hast0001 (författare)
  • Franklin, KarlUmeå universitet,Lungmedicin(Swepub:umu)kafr0021 (författare)
  • Umeå universitetLungmedicin (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Archives of Internal MedicineChicago : American medical association168:3, s. 297-3010003-99261538-3679

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