Search: WFRF:(Wikner Anna) >
Exercise capacity i...
Exercise capacity in adult patients with tetralogy of Fallot
-
- Sandström, Anette (author)
- Umeå universitet,Avdelningen för medicin,Umeå Univ, Heart Ctr, Umeå, Sweden.;Umeå Univ, Dept Publ Hlth & Clin Med, Umeå, Sweden.
-
- Wikner, Anna (author)
- Umeå universitet,Avdelningen för medicin,Umeå Univ, Heart Ctr, Umeå, Sweden.;Umeå Univ, Dept Publ Hlth & Clin Med, Umeå, Sweden.
-
- Rinnström, Daniel, 1982- (author)
- Umeå universitet,Klinisk fysiologi,Avdelningen för medicin,Umeå Univ, Heart Ctr, Umeå, Sweden.;Umeå Univ, Dept Publ Hlth & Clin Med, Umeå, Sweden.;Umeå Univ, Dept Surg & Perioperat Sci, Umeå, Sweden.
-
show more...
-
- Sandberg, Camilla (author)
- Umeå universitet,Institutionen för samhällsmedicin och rehabilitering,Avdelningen för medicin,Umeå Univ, Heart Ctr, Umeå, Sweden.;Umeå Univ, Dept Publ Hlth & Clin Med, Umeå, Sweden.;Umeå Univ, Dept Community Hlth & Rehabil, Umeå, Sweden.
-
- Christersson, Christina (author)
- Uppsala universitet,Kardiologi
-
- Dellborg, Mikael (author)
- Department of Molecular and Clinical Medicine, University of Gothenburg, Sweden,Univ Gothenburg, Dept Mol & Clin Med, Gothenburg, Sweden.
-
- Nielsen, Niels Erik (author)
- Department of Medical and Health Sciences, Linköping University, Sweden,Linköping Univ, Dept Med & Hlth Sci, Linköping, Sweden.
-
- Sörensson, Peder (author)
- Department of Medicine Solna, Karolinska Institutet Stockholm, Sweden,Karolinska Inst, Dept Med Solna, Stockholm, Sweden.
-
- Thilén, Ulf (author)
- Department of Cardiology, Clinical Sciences, Skåne University Hospital, Sweden,Skane Univ Hosp, Dept Cardiol, Clin Sci, Malmö, Sweden.
-
- Johansson, Bengt (author)
- Umeå universitet,Kirurgi,Avdelningen för medicin,Umeå Univ, Heart Ctr, Umeå, Sweden.;Umeå Univ, Dept Publ Hlth & Clin Med, Umeå, Sweden.;Umeå Univ, Dept Surg & Perioperat Sci, Umeå, Sweden.
-
show less...
-
(creator_code:org_t)
- Elsevier, 2021
- 2021
- English.
-
In: International Journal of Cardiology Congenital Heart Disease. - : Elsevier. - 2666-6685. ; 5
- Related links:
-
https://doi.org/10.1...
-
show more...
-
https://umu.diva-por... (primary) (Raw object)
-
https://doi.org/10.1...
-
https://uu.diva-port... (primary) (Raw object)
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
https://urn.kb.se/re...
-
show less...
Abstract
Subject headings
Close
- Background: On a group level, patients with repaired tetralogy of Fallot have impaired exercise capacity. Since exercise capacity is related to prognosis, and more patients survive into higher age, it is important to know the expected exercise capacity at different ages. Furthermore, factors associated with exercise capacity and the relation between exercise capacity and mortality need further evaluation.Methods: The national register of congenital heart disease was searched for exercise tests in adults with repaired tetralogy of Fallot. The results from exercise tests were compared with national reference data.Results: 314 patients were identified (median age 33.2 [IQR 24.8-44.7], 40.8% women). The mean percent of predicted workload was 74.8 (±19.6) % without change across ages. In multivariable analysis, NYHA class I (odds ratio [OR]4.2, 95% confidence interval [CI]1.7-10.0) and higher physical activity level (>3 h/week) (OR 3.6, 95%CI 1.8-7.3) were positively associated with higher exercise capacity, while ongoing cardiovascular therapy (OR 0.4, 95%CI 0.2-0.7) and male sex (OR 0.3, 95%CI 0.2-0.6) were negatively associated with higher exercise capacity. Both exercise capacity (HR 0.96, 95%CI 0.93-0.98) and heart rate reserve (HR 0.96, 95%CI 0.94-0.98) were associated with mortality.Conclusions: In patients with repaired tetralogy of Fallot the exercise capacity was approximately 75% of expected, regardless of age. Patients with better NYHA class and high physical activity level had a higher exercise capacity. Low exercise capacity and low heart rate reserve were associated with higher mortality. Therefore, evaluating exercise capacity as part of follow up is of importance.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Keyword
- Adult congenital heart disease
- Tetralogy of Fallot
- Exercise test
- Exercise capacity
- Register
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
-
Sandström, Anett ...
-
Wikner, Anna
-
Rinnström, Danie ...
-
Sandberg, Camill ...
-
Christersson, Ch ...
-
Dellborg, Mikael
-
show more...
-
Nielsen, Niels E ...
-
Sörensson, Peder
-
Thilén, Ulf
-
Johansson, Bengt
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Cardiac and Card ...
- Articles in the publication
-
International Jo ...
- By the university
-
Umeå University
-
Uppsala University