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TUBE project: Transport-derived ultrafines and the brain effects

Martikainen, Maria-Viola (författare)
Department of Environmental and Biological Sciences, University of Eastern Finland, Kuopio, Finland
Aakko-Saksa, Päivi (författare)
VTT Technical Research Centre of Finland Ltd., Espoo, Finland
Broek, Lenie van den (författare)
Mimetas BV, Oegstgeest, Netherlands
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Cassee, Flemming R. (författare)
Centre for Sustainability, Environment and Health, National Institute for Public Health and the Environment (RIVM), Bilthoven, Netherlands; Institute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, Netherlands
Carare, Roxana O. (författare)
Faculty of Medicine, University of Southampton, Southampton, United Kingdom
Chew, Sweelin (författare)
A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland
Dinnyes, Andras (författare)
Biotalentum Ltd., Godollo, Hungary
Giugno, Rosalba (författare)
Computer Science Department, University of Verona, Verona, Italy
Kanninen, Katja M. (författare)
A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland
Malm, Tarja (författare)
A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland
Muala, Ala (författare)
Umeå universitet,Avdelningen för medicin
Nedergaard, Maiken (författare)
Center for Translational Neuromedicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Oudin, Anna (författare)
Umeå universitet,Avdelningen för medicin
Oyola, Pedro (författare)
Centro Mario Molina Chile, Strategic Studies Department, Santiago, Chile
Pfeiffer, Tobias V. (författare)
VSParticle B.V., Delft, Netherlands
Rönkkö, Topi (författare)
Aerosol Physics Laboratory, Physics Unit, Faculty of Engineering and Natural Sciences, Tampere University, Tampere, Finland
Saarikoski, Sanna (författare)
Atmospheric Composition Research, Finnish Meteorological Institute, Helsinki, Finland
Sandström, Thomas, 1957- (författare)
Umeå universitet,Avdelningen för medicin
Schins, Roel P.F. (författare)
IUF—Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany
Topinka, Jan (författare)
Department of Genetic Toxicology and Epigenetics, Institute of Experimental Medicine of the CAS, Videnska 1083, Prague, Czech Republic
Yang, Mo (författare)
Department of Environmental and Biological Sciences, University of Eastern Finland, Kuopio, Finland
Zeng, Xiaowen (författare)
Guangdong Provincial Engineering Technology Research Center of Environmental Pollution and Health Risk Assessment, Department of Occupational and Environmental Health, School of Public Health, Sun Yat-sen University, Guangzhou, China
Westerink, Remco H.S. (författare)
Institute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, Netherlands
Jalava, Pasi I. (författare)
Department of Environmental and Biological Sciences, University of Eastern Finland, Kuopio, Finland
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Department of Environmental and Biological Sciences, University of Eastern Finland, Kuopio, Finland VTT Technical Research Centre of Finland Ltd, Espoo, Finland (creator_code:org_t)
2021-12-28
2022
Engelska.
Ingår i: International Journal of Environmental Research and Public Health. - : MDPI. - 1661-7827 .- 1660-4601. ; 19:1
Relaterad länk:
https://doi.org/10.3...
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https://umu.diva-por... (primary) (Raw object)
https://www.mdpi.com...
https://urn.kb.se/re...
https://doi.org/10.3...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • The adverse effects of air pollutants on the respiratory and cardiovascular systems are unquestionable. However, in recent years, indications of effects beyond these organ systems have become more evident. Traffic-related air pollution has been linked with neurological diseases, exacerbated cognitive dysfunction, and Alzheimer’s disease. However, the exact air pollutant compositions and exposure scenarios leading to these adverse health effects are not known. Although several components of air pollution may be at play, recent experimental studies point to a key role of ultrafine particles (UFPs). While the importance of UFPs has been recognized, almost nothing is known about the smallest fraction of UFPs, and only >23 nm emissions are regulated in the EU. Moreover, the role of the semivolatile fraction of the emissions has been neglected. The Transport-Derived Ultrafines and the Brain Effects (TUBE) project will increase knowledge on harmful ultrafine air pollutants, as well as semivolatile compounds related to adverse health effects. By including all the major current combustion and emission control technologies, the TUBE project aims to provide new information on the adverse health effects of current traffic, as well as information for decision makers to develop more effective emission legislation. Most importantly, the TUBE project will include adverse health effects beyond the respiratory system; TUBE will assess how air pollution affects the brain and how air pollution particles might be removed from the brain. The purpose of this report is to describe the TUBE project, its background, and its goals.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)

Nyckelord

Air pollution
Brain
CNS
Particulate matter
Toxicology
Traffic
UFP

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