Neurochemical and Hormonal Contributors to Compulsive Sexual Behavior Disorder

Chatzittofis, AndreasUmeå universitet,Psykiatri,Medical School, University of Cyprus, Palaios Dromos Lefkosias Lemesou No.215/6 2029 Aglantzia, Nicosia, Cyprus (author)

Purpose of Review: Compulsive sexual behavior disorder has been recently included in the 11th revision of the International Classification of Diseases (ICD-11), and the possible contribution of neurochemical and hormonal factors have been reported. However, relatively little is known concerning the neurobiology underlying this disorder. The aim of this article is to review and discuss published findings in the area.Recent Findings: Evidence suggests that the neuroendocrine systems are involved in the pathophysiology of compulsive sexual behavior. The hypothalamus-pituitary adrenal axis, the hypothalamus-pituitary–gonadal axis, and the oxytocinergic system have been implicated.Summary: Further studies are needed to elucidate the exact involvement of neuroendocrine and hormonal systems in compulsive sexual behavior disorder. Prospective longitudinal studies are particularly needed, especially those considering co-occurring psychiatric disorders and obtaining hormonal assessments in experimental circumstances with appropriate control groups.

Boström, Adrian Desai E.Umeå universitet,Psykiatri,Neuropaediatric Unit, Department of Women’s and Children’s Health, Karolinska Institutet, Stockholm, Sweden(Swepub:umu)adbo0015 (author)
Savard, JosephineUmeå universitet,Psykiatri(Swepub:umu)joesad04 (author)
Öberg, Katarina GörtsDepartment of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden (author)
Arver, StefanDepartment of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden (author)
Jokinen, JussiKarolinska Institutet,Umeå universitet,Psykiatri,Department of Clinical Neuroscience/Psychiatry, Karolinska Institutet, Stockholm, Sweden(Swepub:umu)jujo0022 (author)
Umeå universitetPsykiatri (creator_code:org_t)

By the author/editor: Chatzittofis, An ...; Boström, Adrian ...; Savard, Josephin ...; Öberg, Katarina ...; Arver, Stefan; Jokinen, Jussi

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Psychiatry

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