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Development and val...
Development and validation of combined symptom-medication scores for allergic rhinitis*
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- Sousa-Pinto, Bernardo (författare)
- MEDCIDS - Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal; CINTESIS - Center for Health Technology and Services Research, University of Porto, Porto, Portugal
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- Azevedo, Luís Filipe (författare)
- MEDCIDS - Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal; CINTESIS - Center for Health Technology and Services Research, University of Porto, Porto, Portugal
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- Jutel, Marek (författare)
- Department of Clinical Immunology, Wrocław Medical University, Wroclaw, Poland; ALL-MED Medical Research Institute, Wroclaw, Poland
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- Agache, Ioana (författare)
- Faculty of Medicine, Transylvania University, Brasov, Romania
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- Canonica, G. Walter (författare)
- Department of Biomedical Sciences, Humanitas University, Milan, Italy; Personalized Medicine, Asthma & Allergy -Humanitas Clinical & Research Centre, IRCCS, Rozzano, Italy
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- Czarlewski, Wienczyslawa (författare)
- Medical Consulting Czarlewski, Levallois, France; ARIA, Montpellier, France
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- Papadopoulos, Nikolaos G. (författare)
- Allergy Department, 2nd Pediatric Clinic, Athens General Children's Hospital “P&A Kyriakou”, University of Athens, Athens, Greece
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- Bergmann, Karl-Christian (författare)
- Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, Berlin, Germany; Institute for Allergology, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
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- Devillier, Philippe (författare)
- UPRES EA220, Pôle des Maladies des Voies Respiratoires, Hôpital Foch, Université Paris-Saclay, Suresnes, France
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- Laune, Daniel (författare)
- KYomed INNOV, Montpellier, France
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- Klimek, Ludger (författare)
- Department of Otolaryngology, Head and Neck Surgery, Universitätsmedizin Mainz, Mainz, Germany; Center for Rhinology and Allergology, Wiesbaden, Germany
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- Anto, Aram (författare)
- ARIA, Montpellier, France
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- Anto, Josep M. (författare)
- ISGlobAL, Barcelona Institute for Global Health, Barcelona, Spain; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain; Universitat Pompeu Fabra (UPF), Barcelona, Spain; CIBER Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain
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- Eklund, Patrik (författare)
- Umeå universitet,Institutionen för datavetenskap
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- Almeida, Rute (författare)
- MEDCIDS - Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal; CINTESIS - Center for Health Technology and Services Research, University of Porto, Porto, Portugal
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- Bedbrook, Anna (författare)
- MACVIA-France, Montpellier, France
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- Bosnic-Anticevich, Sinthia (författare)
- Quality Use of Respiratory Medicine Group, Woolcock Institute of Medical Research, The University of Sydney, NSW, Sydney, Australia; Sydney Local Health District, NSW, Sydney, Australia
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- Brough, Helen A. (författare)
- Division of Allergy/Immunology, University of South Florida, FL, Tampa, United States
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- Brussino, Luisa (författare)
- Department of Medical Sciences, Allergy and Clinical Immunology Unit, University of Torino & Mauriziano Hospital, Torino, Italy
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- Cardona, Victoria (författare)
- Allergy Section, Department of Internal Medicine, Hospital Vall d'Hebron & ARADyAL Research Network, Barcelona, Spain
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- Casale, Thomas (författare)
- Division of Allergy/Immunology, University of South Florida, FL, Tampa, United States
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- Cecchi, Lorenzo (författare)
- SOS Allergology and Clinical Immunology, USL Toscana Centro, Prato, Italy
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- Charpin, Denis (författare)
- Clinique des Bronches, Allergie et Sommeil, Hôpital Nord, Marseille, France
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- Chivato, Tomás (författare)
- School of Medicine, University CEU San Pablo, Madrid, Spain
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- Costa, Elisio M. (författare)
- Karolinska Institutet
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- Cruz, Alvaro A. (författare)
- Fundaçao ProAR, Federal University of Bahia and GARD/WHO Planning Group, Salvador, Brazil
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- Dramburg, Stephanie (författare)
- Department of Pediatric Pneumology, Immunology and Intensive Care Medicine, Charité Medical University, Berlin, Germany
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- Durham, Stephen R. (författare)
- Allergy and Clinical Immunology, National Heart and Lung Institute, Imperial College London, London, United Kingdom
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- De Feo, Giulia (författare)
- Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, Salerno, Italy
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- Gerth van Wijk, Roy (författare)
- Section of Allergology, Department of Internal Medicine, Erasmus MC, Rotterdam, Netherlands
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- Fokkens, Wystke J. (författare)
- Department of Otorhinolaryngology, Amsterdam University Medical Centres, Amsterdam, Netherlands
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- Gemicioglu, Bilun (författare)
- Department of Pulmonary Diseases, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey
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- Haahtela, Tari (författare)
- Skin and Allergy Hospital, Helsinki University Hospital, University of Helsinki, Helsinki, Finland
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- Illario, Maddalena (författare)
- Department of Public Health and Research and Development Unit, Federico II University and Hospital, Naples, Italy
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- Ivancevich, Juan Carlos (författare)
- Servicio de Alergia e Immunologia, Clinica Santa Isabel, Buenos Aires, Argentina
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- Kvedariene, Violeta (författare)
- Department of Pathology, Faculty of Medicine, Institute of Biomedical Sciences, Vilnius University, Vilnius, Lithuania; Faculty of Medicine, Institute of Clinical Medicine, Clinic of Chest Diseases and Allergology, Vilnius University, Vilnius, Lithuania
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- Kuna, Piotr (författare)
- Division of Internal Medicine, Asthma and Allergy, Barlicki University Hospital, Medical University of Lodz, Poland
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- Larenas-Linnemann, Désirée E. (författare)
- Center of Excellence in Asthma and Allergy, Médica Sur Clinical Foundation and Hospital, México City, Mexico
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- Makris, Michael (författare)
- Allergy Unit “D Kalogeromitros”, 2nd Department of Dermatology and Venereology, National & Kapodistrian University of Athens, “Attikon” University Hospital, Athens, Greece
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- Mathieu-Dupas, Eve (författare)
- KYomed INNOV, Montpellier, France
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- Melén, Erik (författare)
- Sachs’ Children and Youth Hospital, Södersjukhuset, Stockholm, Sweden; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
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- Morais-Almeida, Mario (författare)
- Allergy Center, CUF Descobertas Hospital, Lisbon, Portugal
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- Mösges, Ralph (författare)
- CRI-Clinical Research International-Ltd, Hamburg, Germany
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- Mullol, Joaquim (författare)
- Rhinology Unit & Smell Clinic, ENT Department, Hospital Clínic, Barcelona, Spain; Clinical & Experimental Respiratory Immunoallergy, IDIBAPS, CIBERES, University of Barcelona, Barcelona, Spain
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- Nadeau, Kari C. (författare)
- Sean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, CA, Stanford, United States
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- Pham-Thi, Nhân (författare)
- IRBA (Institut de Recherche bio-Médicale des Armées), Ecole Polytechnique Palaiseau, Bretigny, France
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- O’Hehir, Robyn (författare)
- Department of Allergy, Immunology and Respiratory Medicine, Central Clinical School, Monash University and Alfred Health, VIC, Melbourne, Australia
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- Regateiro, Frederico S. (författare)
- Allergy and Clinical Immunology Unit, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal; Institute of Immunology, Faculty of Medicine, University of Coimbra, Portugal; ICBR - Coimbra Institute for Clinical and Biomedical Research, CIBB, Coimbra, Portugal
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- Reitsma, Sietze (författare)
- Department of Otorhinolaryngology, Amsterdam University Medical Centres, AMC, Amsterdam, Netherlands
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- Samolinski, Boleslaw (författare)
- Department of Prevention of Environmental Hazards, Allergology and Immunology, Medical University of Warsaw, Warsaw, Poland
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- Sheikh, Aziz (författare)
- Usher Institute, The University of Edinburgh, Edinburgh, United Kingdom
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- Stellato, Cristiana (författare)
- Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, Salerno, Italy
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- Todo-Bom, Ana (författare)
- Imunoalergologia, Centro Hospitalar Universitário de Coimbra and Faculty of Medicine, University of Coimbra, Coimbra, Portugal
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- Tomazic, Peter Valentin (författare)
- Department of General ORL, H&NS, Medical University of Graz, ENT-University Hospital Graz, Austria
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- Toppila-Salmi, Sanna (författare)
- Skin and Allergy Hospital, Helsinki University Hospital and University of Helsinki, Helsinki, Finland
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- Valero, Antonio (författare)
- Pneumology and Allergy Department CIBERES and Clinical & Experimental Respiratory Immunoallergy, IDIBAPS, University of Barcelona, Spain
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- Valiulis, Arunas (författare)
- Faculty of Medicine, Institute of Clinical Medicine & Institute of Health Sciences, Vilnius University, Vilnius, Lithuania; European Academy of Paediatrics (EAP/UEMS-SP), Brussels, Belgium
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- Ventura, Maria Teresa (författare)
- Unit of Geriatric Immunoallergology, University of Bari Medical School, Bari, Italy
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- Wallace, Dana (författare)
- Nova Southeastern University, FL, Fort Lauderdale, United States
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- Waserman, Susan (författare)
- Department of Medicine, Clinical Immunology and Allergy, McMaster University, ON, Hamilton, Canada
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- Yorgancioglu, Arzu (författare)
- Department of Pulmonary Diseases, Faculty of Medicine, Celal Bayar University, Manisa, Turkey
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- De Vries, Govert (författare)
- Peercode BV, Geldermalsen, Netherlands
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- van Eerd, Michiel (författare)
- Peercode BV, Geldermalsen, Netherlands
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- Zieglmayer, Petra (författare)
- Vienna Challenge Chamber, Vienna, Austria; Competence Center for Allergology and Immunology, Karl Landsteiner University, Krems, Austria
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- Zuberbier, Torsten (författare)
- Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, Berlin, Germany; Institute for Allergology, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
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- Pfaar, Oliver (författare)
- Section of Rhinology and Allergy, Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Marburg, Philipps-Universität Marburg, Marburg, Germany
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- Almeida Fonseca, João (författare)
- Departamento Medicina da Comunidade, Informaçao e Decisao em Saude (MEDCIDS), Faculdada de Medicina da Universidade do Porto, Porto, Portugal; Medicina, EDucaçao, I&D e Avaliaçao, Lda (MEDIDA), Porto, Portugal; Imunoalergologia, CUF, Porto, Portugal
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- Bousquet, Jean (författare)
- Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, Berlin, Germany; Institute for Allergology, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; MACVIA-France, Montpellier, France; University Hospital Montpellier, Montpellier, France
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Nhan, PH (författare)
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(creator_code:org_t)
- 2022-01-15
- 2022
- Engelska.
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Ingår i: Allergy. European Journal of Allergy and Clinical Immunology. - : John Wiley & Sons. - 0105-4538 .- 1398-9995. ; 77:7, s. 2147-2162
- Relaterad länk:
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https://doi.org/10.1...
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https://umu.diva-por... (primary) (Raw object)
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https://onlinelibrar...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Background: Validated combined symptom-medication scores (CSMSs) are needed to investigate the effects of allergic rhinitis treatments. This study aimed to use real-life data from the MASK-air® app to generate and validate hypothesis- and data-driven CSMSs.Methods: We used MASK-air® data to assess the concurrent validity, test-retest reliability and responsiveness of one hypothesis-driven CSMS (modified CSMS: mCSMS), one mixed hypothesis- and data-driven score (mixed score), and several data-driven CSMSs. The latter were generated with MASK-air® data following cluster analysis and regression models or factor analysis. These CSMSs were compared with scales measuring (i) the impact of rhinitis on work productivity (visual analogue scale [VAS] of work of MASK-air®, and Work Productivity and Activity Impairment: Allergy Specific [WPAI-AS]), (ii) quality-of-life (EQ-5D VAS) and (iii) control of allergic diseases (Control of Allergic Rhinitis and Asthma Test [CARAT]).Results: We assessed 317,176 days of MASK-air® use from 17,780 users aged 16-90 years, in 25 countries. The mCSMS and the factor analyses-based CSMSs displayed poorer validity and responsiveness compared to the remaining CSMSs. The latter displayed moderate-to-strong correlations with the tested comparators, high test-retest reliability and moderate-to-large responsiveness. Among data-driven CSMSs, a better performance was observed for cluster analyses-based CSMSs. High accuracy (capacity of discriminating different levels of rhinitis control) was observed for the latter (AUC-ROC = 0.904) and for the mixed CSMS (AUC-ROC = 0.820).Conclusion: The mixed CSMS and the cluster-based CSMSs presented medium-high validity, reliability and accuracy, rendering them as candidates for primary endpoints in future rhinitis trials.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
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Sousa-Pinto, Ber ...
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Azevedo, Luís Fi ...
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Jutel, Marek
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Agache, Ioana
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Canonica, G. Wal ...
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Czarlewski, Wien ...
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Papadopoulos, Ni ...
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Bergmann, Karl-C ...
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Devillier, Phili ...
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Laune, Daniel
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Klimek, Ludger
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Anto, Aram
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Anto, Josep M.
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Eklund, Patrik
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Almeida, Rute
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Bedbrook, Anna
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Bosnic-Anticevic ...
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Brough, Helen A.
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Brussino, Luisa
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Cardona, Victori ...
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Casale, Thomas
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Cecchi, Lorenzo
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Charpin, Denis
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Chivato, Tomás
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Costa, Elisio M.
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Cruz, Alvaro A.
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Dramburg, Stepha ...
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Durham, Stephen ...
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De Feo, Giulia
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Gerth van Wijk, ...
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Fokkens, Wystke ...
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Gemicioglu, Bilu ...
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Haahtela, Tari
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Illario, Maddale ...
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Ivancevich, Juan ...
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Kvedariene, Viol ...
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Kuna, Piotr
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Larenas-Linneman ...
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Makris, Michael
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Mathieu-Dupas, E ...
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Melén, Erik
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Morais-Almeida, ...
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Mösges, Ralph
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Mullol, Joaquim
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Nadeau, Kari C.
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Pham-Thi, Nhân
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O’Hehir, Robyn
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Regateiro, Frede ...
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Reitsma, Sietze
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Samolinski, Bole ...
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Sheikh, Aziz
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Stellato, Cristi ...
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Todo-Bom, Ana
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Tomazic, Peter V ...
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Toppila-Salmi, S ...
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Valero, Antonio
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Valiulis, Arunas
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Ventura, Maria T ...
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Wallace, Dana
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Waserman, Susan
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Yorgancioglu, Ar ...
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De Vries, Govert
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van Eerd, Michie ...
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Zieglmayer, Petr ...
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Zuberbier, Torst ...
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Pfaar, Oliver
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Almeida Fonseca, ...
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Bousquet, Jean
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Nhan, PH
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Umeå universitet
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