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Neither low social support nor low decision latitude at work is associated with disease remission among patients with rheumatoid arthritis : results from the Swedish EIRA study

Hedenstierna, Louise (author)
Department of Medicine, Karolinska Institutet, Stockholm, Solna, Sweden; Academic Specialist Center, Stockholm Health Services, Stockholm, Sweden; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; Center for Rheumatology, Karolinska Institutet, Stockholm, Sweden
Hedström, Anna Karin (author)
Karolinska Institutet
Klareskog, Lars (author)
Karolinska Institutet
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Di Giuseppe, Daniela (author)
Karolinska Institutet
Alfredsson, Lars (author)
Karolinska Institutet
Askling, Johan (author)
Karolinska Institutet
Ernestam, Sofia (author)
Karolinska Institutet
Saevarsdottir, Saedis (author)
Karolinska Institutet
Ljung, Lotta, 1964- (author)
Karolinska Institutet,Umeå universitet,Reumatologi,Department of Medicine, Karolinska Institutet, Stockholm, Solna, Sweden; Academic Specialist Center, Stockholm Health Services, Stockholm, Sweden
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 (creator_code:org_t)
BioMed Central, 2022
2022
English.
In: Arthritis Research & Therapy. - : BioMed Central. - 1478-6362. ; 24:1
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • OBJECTIVES: To investigate the association between psychosocial vulnerability, defined as either low social support or low decision latitude at work, and disease remission at 3, 12, and 60 months in patients with rheumatoid arthritis (RA).METHODS: This cohort study included all patients enrolled in both the Swedish Epidemiological Investigation of Rheumatoid Arthritis (EIRA) 1996-2015 and the Swedish Rheumatology Quality Register (SRQ, n = 2820). Information on social support and decision latitude at work at RA diagnosis were identified from the EIRA questionnaire. Indexes for levels of social support and decision latitude at work, respectively, were calculated based on the questionnaire. Low social support and low decision latitude at work, respectively, were identified by a score in the lowest quartile and compared with the three other quartiles (not low). Disease-activity parameters were retrieved from SRQ at 3, 12, and 60 months. The associations between social support or decision latitude at work, respectively, and Disease Activity Score 28 joint count with C-reactive protein (DAS28-CRP) remission were analysed using logistic regression models adjusted for age, sex, smoking habits, alcohol habits, symptom duration, and educational level.RESULTS: Having low social support (n = 591) was not associated with DAS28-CRP remission at 3 (OR 0.93, 95% CI 0.74-1.16), 12 (OR 0.96, 95%CI 0.75-1.23), or 60 (OR 0.89, 95%CI 0.72-1.10) months compared to not low social support (n = 2209). No association was observed for low (n = 212) versus not low (n = 635) decision latitude at work and DAS28-CRP remission at 3 (OR 0.84, 95%CI 0.54-1.31), 12 (OR 0.81, 95%CI 0.56-1.16), or 60 (OR 1.37, 95%CI 0.94-2.01) months.CONCLUSION: In a country with general access to healthcare, psychosocial vulnerability does not influence the likelihood of achieving remission in early RA.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)

Publication and Content Type

ref (subject category)
art (subject category)

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