Search: WFRF:(Becker Diane M.)
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Gene-educational at...
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de las Fuentes, LisaCardiovascular Division, Department of Medicine, Washington University, MO, St. Louis, United States; Division of Biostatistics, Washington University School of Medicine, MO, St. Louis, United States
(author)
Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci
- Article/chapterEnglish2021
Publisher, publication year, extent ...
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2020-05-05
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Springer Nature,2021
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:umu-202954
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-202954URI
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https://doi.org/10.1038/s41380-020-0719-3DOI
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https://lup.lub.lu.se/record/68ba99eb-1ebd-429c-9334-6fe650418f71URI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:143615829URI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Educational attainment is widely used as a surrogate for socioeconomic status (SES). Low SES is a risk factor for hypertension and high blood pressure (BP). To identify novel BP loci, we performed multi-ancestry meta-analyses accounting for gene-educational attainment interactions using two variables, “Some College” (yes/no) and “Graduated College” (yes/no). Interactions were evaluated using both a 1 degree of freedom (DF) interaction term and a 2DF joint test of genetic and interaction effects. Analyses were performed for systolic BP, diastolic BP, mean arterial pressure, and pulse pressure. We pursued genome-wide interrogation in Stage 1 studies (N = 117 438) and follow-up on promising variants in Stage 2 studies (N = 293 787) in five ancestry groups. Through combined meta-analyses of Stages 1 and 2, we identified 84 known and 18 novel BP loci at genome-wide significance level (P < 5 × 10-8). Two novel loci were identified based on the 1DF test of interaction with educational attainment, while the remaining 16 loci were identified through the 2DF joint test of genetic and interaction effects. Ten novel loci were identified in individuals of African ancestry. Several novel loci show strong biological plausibility since they involve physiologic systems implicated in BP regulation. They include genes involved in the central nervous system-adrenal signaling axis (ZDHHC17, CADPS, PIK3C2G), vascular structure and function (GNB3, CDON), and renal function (HAS2 and HAS2-AS1, SLIT3). Collectively, these findings suggest a role of educational attainment or SES in further dissection of the genetic architecture of BP.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
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Sung, Yun JuDivision of Biostatistics, Washington University School of Medicine, MO, St. Louis, United States
(author)
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Noordam, RaymondSection of Gerontology and Geriatrics, Department of Internal Medicine, Leiden University Medical Center, Leiden, Netherlands
(author)
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Winkler, ThomasDepartment of Genetic Epidemiology, University of Regensburg, Regensburg, Germany
(author)
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Feitosa, Mary F.Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, MO, St. Louis, United States
(author)
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Schwander, KarenDivision of Biostatistics, Washington University School of Medicine, MO, St. Louis, United States
(author)
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Bentley, Amy R.Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, MD, Bethesda, United States
(author)
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Brown, Michael R.Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, TX, Houston, United States
(author)
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Guo, XiuqingThe Institute for Translational Genomics and Population Sciences, Division of Genomic Outcomes, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, CA, Torrance, United States
(author)
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Manning, AlisaClinical and Translational Epidemiology Unit, Massachusetts General Hospital, MA, Boston, United States; Department of Medicine, Harvard Medical School, MA, Boston, United States
(author)
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Chasman, Daniel I.Division of Preventive Medicine, Brigham and Women’s Hospital, MA, Boston, United States; Harvard Medical School, MA, Boston, United States
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Aschard, HuguesDepartment of Epidemiology, Harvard School of Public Health, MA, Boston, United States; Centre de Bioinformatique, Biostatistique et Biologie Intégrative (C3BI), Institut Pasteur, Paris, France
(author)
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Bartz, Traci M.Cardiovascular Health Research Unit, Biostatistics and Medicine, University of Washington, WA, Seattle, United States
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Bielak, Lawrence F.Department of Epidemiology, School of Public Health, University of Michigan, MI, Ann Arbor, United States
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Campbell, ArchieCentre for Genomic & Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom
(author)
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Cheng, Ching-YuOcular Epidemiology, Singapore Eye Research Institute, Singapore National Ecy Centre, Singapore, Singapore; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore
(author)
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Dorajoo, RajkumarGenome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore
(author)
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Hartwig, Fernando P.Postgraduate Programme in Epidemiology, Federal University of Pelotas, RS, Pelotas, Brazil; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom
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Horimoto, A.R.V.R.Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, SP, São Paulo, Brazil
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Li, ChangweiEpidemiology and Biostatistics, University of Georgia at Athens College of Public Health, GA, Athens, United States
(author)
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Li-Gao, RuifangDepartment of Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands
(author)
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Liu, YongmeiPublic Health Sciences, Epidemiology and Prevention, Wake Forest University Health Sciences, NC, Winston-Salem, United States
(author)
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Marten, JonathanMedical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom
(author)
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Musani, Solomon K.Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, MS, Jackson, United States
(author)
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Ntalla, IoannaClinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
(author)
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Rankinen, TuomoHuman Genomics Laboratory, Pennington Biomedical Research Center, LA, Baton Rouge, United States
(author)
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Richard, MelissaInstitute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, TX, Houston, United States
(author)
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Sim, XuelingSaw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore
(author)
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Smith, Albert V.Department of Biostatistics, University of Michigan, MI, Ann Arbor, United States; Icelandic Heart Association, Kopavogur, Iceland
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Tajuddin, Salman M.Health Disparities Research Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, MD, Baltimore, United States
(author)
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Tayo, Bamidele O.Department of Public Health Sciences, Loyola University Chicago, IL, Maywood, United States
(author)
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Vojinovic, DinaDepartment of Epidemiology, Erasmus University Medical Center, Rotterdam, Netherlands
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Warren, Helen R.Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom; NIHR Barts Cardiovascular Biomedical Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, London, United Kingdom
(author)
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Xuan, DengBiostatistics, Boston University School of Public Health, MA, Boston, United States
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Alver, MarisEstonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia; Department of Biotechnology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia
(author)
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Boissel, MathildeCNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France
(author)
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Chai, Jin-FangSaw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore
(author)
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Chen, XuDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Stockholm, Sweden
(author)
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Christensen, KaareUnit of Epidemiology, Biostatistics and Biodemography, Department of Public Health, Southern Denmark University, Odense, Denmark
(author)
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Divers, JasminBiostatistical Sciences, Public Health Sciences, Wake Forest School of Medicine, NC, Winston-Salem, United States
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Evangelou, EvangelosKarolinska Institutet
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Gao, ChuanMolecular Genetics and Genomics Program, Wake Forest School of Medicine, NC, Winston-Salem, United States
(author)
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Girotto, GiorgiaMedical Genetics, Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy; Institute for Maternal and Child Health–IRCCS “Burlo Garofolo”, Trieste, Italy
(author)
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Harris, Sarah E.Department of Psychology, Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, United Kingdom
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He, MeianDepartment of Occupational and Environmental Health and State Key Laboratory of Environmental Health for Incubating, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
(author)
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Hsu, Fang-ChiBiostatistical Sciences, Public Health Sciences, Wake Forest School of Medicine, NC, Winston-Salem, United States
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Kühnel, BrigitteResearch Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany
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Laguzzi, FedericaKarolinska Institutet
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Li, XiaoyinDepartment of Population and Quantitative Health Sciences, Case Western Reserve University, OH, Cleveland, United States; Department of Mathematics and Statistics, University of Minnesota, MN, Duluth, United States
(author)
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Lyytikäinen, Leo-PekkaDepartment of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, University of Tampere, Tampere, Finland
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Nolte, Ilja M.University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, Netherlands
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Poveda, AlaitzLund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups,Skåne University Hospital(Swepub:lu)med-azp
(author)
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Rauramaa, RainerFoundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland
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Riaz, MuhammadCollege of Medicine, Biological Sciences and Psychology, Health Sciences, The Infant Mortality and Morbidity Studies (TIMMS), Leicester, United Kingdom
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Rueedi, RicoDepartment of Computational Biology, University of Lausanne, Lausanne, Switzerland; Swiss Institute of Bioinformatics, Lausanne, Switzerland
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Shu, Xiao-ouDivision of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, TN, Nashville, United States
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Snieder, HaroldUniversity of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, Netherlands
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Sofer, TamarDivision of Sleep and Circadian Disorders, Brigham and Women’s Hospital, MA, Boston, United States
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Takeuchi, FumihikoDepartment of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan
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Verweij, NiekUniversity of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands
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Ware, Erin B.Survey Research Center, Institute for Social Research, University of Michigan, MI, Ann Arbor, United States
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Weiss, StefanInterfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Health), Partner Site Greifswald, Greifswald, Germany
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Yanek, Lisa R.Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, MD, Baltimore, United States
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Amin, NajafDepartment of Epidemiology, Erasmus University Medical Center, Rotterdam, Netherlands
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Arking, Dan E.McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, MD, Baltimore, United States
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Arnett, Donna K.Dean’s Office, University of Kentucky College of Public Health, KY, Lexington, United States
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Bergmann, SvenDepartment of Computational Biology, University of Lausanne, Lausanne, Switzerland; Swiss Institute of Bioinformatics, Lausanne, Switzerland
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Boerwinkle, EricHuman Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, TX, Houston, United States; Human Genome Sequencing Center, Baylor College of Medicine, TX, Houston, United States
(author)
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Brody, Jennifer A.Cardiovascular Health Research Unit, Medicine, University of Washington, WA, Seattle, United States
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Broeckel, UlrichSection of Genomic Pediatrics, Department of Pediatrics, Medicine and Physiology, Medical College of Wisconsin, WI, Milwaukee, United States
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Brumat, MarcoMedical Genetics, Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy
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Burke, GregoryPublic Health Sciences, Wake Forest School of Medicine, NC, Winston-Salem, United States
(author)
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Cabrera, Claudia P.Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom; NIHR Barts Cardiovascular Biomedical Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, London, United Kingdom
(author)
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Canouil, MickaëlCNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France
(author)
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Chee, Miao LiStatistics Unit, Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore
(author)
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Chen, Yii-Der IdaThe Institute for Translational Genomics and Population Sciences, Division of Genomic Outcomes, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, CA, Torrance, United States
(author)
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Cocca, MassimilianoInstitute for Maternal and Child Health–IRCCS “Burlo Garofolo”, Trieste, Italy
(author)
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Connell, JohnNinewells Hospital & Medical School, University of Dundee, Dundee, United Kingdom
(author)
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de Silva, H. JanakaDepartment of Medicine, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka
(author)
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de Vries, Paul S.Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, TX, Houston, United States
(author)
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Eiriksdottir, GudnyIcelandic Heart Association, Kopavogur, Iceland
(author)
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Faul, Jessica D.Survey Research Center, Institute for Social Research, University of Michigan, MI, Ann Arbor, United States
(author)
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Fisher, VirginiaBiostatistics, Boston University School of Public Health, MA, Boston, United States
(author)
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Forrester, TerrenceTropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona, Jamaica
(author)
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Fox, Ervin F.Cardiology, Medicine, University of Mississippi Medical Center, MS, Jackson, United States
(author)
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Friedlander, YechielBraun School of Public Health, Hebrew University-Hadassah Medical Center, Jerusalem, Israel
(author)
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Gao, HeDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom; MRC-PHE Centre for Environment and Health, Imperial College London, London, United Kingdom
(author)
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Gigante, BrunaKarolinska Institutet
(author)
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Giulianini, FrancoBrigham and Women’s Hospital, MA, Boston, United States
(author)
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Gu, Chi CharlesDivision of Biostatistics, Washington University School of Medicine, MO, St. Louis, United States
(author)
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Gu, DongfengDepartment of Epidemiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
(author)
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Harris, Tamara B.Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, MD, Bethesda, United States
(author)
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He, JiangEpidemiology, Tulane University School of Public Health and Tropical Medicine, LA, New Orleans, United States; Medicine, Tulane University School of Medicine, LA, New Orleans, United States
(author)
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Heikkinen, SamiInstitute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland
(author)
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Heng, Chew-KiatDepartment of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Khoo Teck Puat – National University Children’s Medical Institute, National University Health System, Singapore, Singapore
(author)
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Hunt, StevenCardiovascular Genetics, Department of Internal Medicine, University of Utah, UT, Salt Lake City, United States; Weill Cornell Medicine in Qatar, Doha, Qatar
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Ikram, M. ArfanDepartment of Epidemiology, Erasmus University Medical Center, Rotterdam, Netherlands; Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, Netherlands
(author)
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Irvin, Marguerite R.Department of Biostatistics, University of Alabama at Birmingham, AL, Birmingham, United States
(author)
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Kähönen, MikaDepartment of Clinical Physiology, Tampere University Hospital, Tampere, Finland; Department of Clinical Physiology, Finnish Cardiovascular Research Center–Tampere, Faculty of Medicine and Health Technology, University of Tampere, Tampere, Finland
(author)
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Kavousi, MaryamDepartment of Epidemiology, Erasmus University Medical Center, Rotterdam, Netherlands
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Khor, Chiea ChuenGenome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore; Department of Biochemistry, National University of Singapore, Singapore, Singapore
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Kilpeläinen, Tuomas O.Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Environmental Medicine and Public Health, The Icahn School of Medicine at Mount Sinai, NY, New York, United States
(author)
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Koh, Woon-PuaySaw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore; Health Services and Systems Research, Duke-NUS Medical School, Singapore, Singapore
(author)
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Komulainen, PirjoFoundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland
(author)
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Kraja, Aldi T.Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, MO, St. Louis, United States
(author)
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Krieger, J.E.Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, SP, São Paulo, Brazil
(author)
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Langefeld, Carl D.Biostatistical Sciences, Public Health Sciences, Wake Forest School of Medicine, NC, Winston-Salem, United States
(author)
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Li, YizeDivision of Biostatistics, Washington University School of Medicine, MO, St. Louis, United States
(author)
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Liang, JingjingDepartment of Population and Quantitative Health Sciences, Case Western Reserve University, OH, Cleveland, United States
(author)
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Liewald, David C. M.Department of Psychology, Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, United Kingdom
(author)
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Liu, Ching-TiBiostatistics, Boston University School of Public Health, MA, Boston, United States
(author)
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Liu, JianjunGenome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore
(author)
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Lohman, Kurt K.Public Health Sciences, Biostatistics and Data Science, Wake Forest University Health Sciences, NC, Winston-Salem, United States
(author)
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Mägi, ReedikEstonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia
(author)
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McKenzie, Colin A.Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona, Jamaica
(author)
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Meitinger, ThomasInstitute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Institute of Human Genetics, Technische Universität München, Munich, Germany
(author)
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Metspalu, AndresEstonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia; Department of Biotechnology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia
(author)
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Milaneschi, YuriDepartment of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, VU University Medical Center, Amsterdam, Netherlands
(author)
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Milani, LiliEstonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia
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Mook-Kanamori, Dennis O.Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, Netherlands
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Nalls, Mike A.Molecular Genetics Section, Laboratory of Neurogenetics, National Institute on Aging, MD, Bethesda, United States; Data Tecnica International, MD, Glen Echo, United States
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Nelson, Christopher P.Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, United Kingdom
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Norris, Jill M.Department of Epidemiology, University of Colorado Denver, CO, Aurora, United States
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O’Connell, JeffDivision of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, MD, Baltimore, United States; Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, MD, Baltimore, United States
(author)
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Ogunniyi, AdesolaDepartment of Medicine, University of Ibadan, Oyo, Ibadan, Nigeria
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Padmanabhan, SandoshBritish Heart Foundation Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom
(author)
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Palmer, Nicholette D.Biochemistry, Wake Forest School of Medicine, NC, Winston-Salem, United States
(author)
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Pedersen, Nancy L.Karolinska Institutet
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Perls, ThomasDepartment of Medicine, Geriatrics Section, Boston Medical Center, Boston University School of Medicine, MA, Boston, United States
(author)
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Peters, AnnetteInstitute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Neuherberg, Germany
(author)
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Petersmann, AstridInstitute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany
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Peyser, Patricia A.Department of Epidemiology, School of Public Health, University of Michigan, MI, Ann Arbor, United States
(author)
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Polasek, OzrenUniversity of Split School of Medicine, Split, Croatia; University Hospital Split, Split, Croatia; Psychiatric Hospital “Sveti Ivan”, Zagreb, Croatia
(author)
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Porteous, David J.Centre for Genomic & Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom; Department of Psychology, Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, United Kingdom
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Raffel, Leslie J.Division of Genetic and Genomic Medicine, Department of Pediatrics, University of California, CA, Irvine, United States
(author)
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Rice, Treva K.Division of Biostatistics, Washington University School of Medicine, MO, St. Louis, United States
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Rotter, Jerome I.The Institute for Translational Genomics and Population Sciences, Division of Genomic Outcomes, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, CA, Torrance, United States
(author)
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Rudan, IgorUsher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, United Kingdom
(author)
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Rueda-Ochoa, Oscar-LeonelDepartment of Epidemiology, Erasmus University Medical Center, Rotterdam, Netherlands
(author)
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Sabanayagam, CharumathiOcular Epidemiology, Singapore Eye Research Institute, Singapore National Ecy Centre, Singapore, Singapore; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore
(author)
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Salako, Babatunde L.Department of Medicine, University of Ibadan, Oyo, Ibadan, Nigeria
(author)
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Schreiner, Pamela J.Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, MN, Minneapolis, United States
(author)
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Shikany, James M.Division of Preventive Medicine, School of Medicine, University of Alabama at Birmingham, AL, Birmingham, United States
(author)
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Sidney, Stephen S.Division of Research, Kaiser Permanente of Northern California, CA, Oakland, United States
(author)
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Sims, MarioJackson Heart Study, Department of Medicine, University of Mississippi Medical Center, MS, Jackson, United States
(author)
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Sitlani, Colleen M.Cardiovascular Health Research Unit, Medicine, University of Washington, WA, Seattle, United States
(author)
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Smith, Jennifer A.Department of Epidemiology, School of Public Health, University of Michigan, MI, Ann Arbor, United States; Survey Research Center, Institute for Social Research, University of Michigan, MI, Ann Arbor, United States
(author)
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Starr, John M.Alzheimer Scotland Dementia Research Centre, The University of Edinburgh, Edinburgh, United Kingdom; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, United Kingdom
(author)
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Strauch, KonstantinInstitute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Institute of Medical Informatics Biometry and Epidemiology, Ludwig-Maximilians-Universitat Munchen, Munich, Germany
(author)
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Swertz, Morris A.University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, Netherlands
(author)
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Teumer, AlexanderDZHK (German Centre for Cardiovascular Health), Partner Site Greifswald, Greifswald, Germany; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany
(author)
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Tham, Yih ChungOcular Epidemiology, Singapore Eye Research Institute, Singapore National Ecy Centre, Singapore, Singapore
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Uitterlinden, André G.Department of Epidemiology, Erasmus University Medical Center, Rotterdam, Netherlands; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, Netherlands
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Vaidya, DhananjayDivision of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, MD, Baltimore, United States
(author)
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van der Ende, M. YldauUniversity of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands
(author)
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Waldenberger, MelanieResearch Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Neuherberg, Germany
(author)
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Wang, LihuaDivision of Statistical Genomics, Department of Genetics, Washington University School of Medicine, MO, St. Louis, United States
(author)
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Wang, Ya-XingBeijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Ophthalmology and Visual Science Key Lab, Beijing Tongren Hospital, Capital Medical University, Beijing, China
(author)
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Wei, Wen-BinBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China
(author)
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Weir, David R.Survey Research Center, Institute for Social Research, University of Michigan, MI, Ann Arbor, United States
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Wen, WanqingDivision of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, TN, Nashville, United States
(author)
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Yao, JieThe Institute for Translational Genomics and Population Sciences, Division of Genomic Outcomes, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, CA, Torrance, United States
(author)
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Yu, BingHuman Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, TX, Houston, United States
(author)
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Yu, CaizhengDepartment of Occupational and Environmental Health and State Key Laboratory of Environmental Health for Incubating, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
(author)
-
Yuan, Jian-MinDepartment of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA, Pittsburgh, United States; Division of Cancer Control and Population Sciences, UPMC Hillman Cancer, , University of Pittsburgh, PA, Pittsburgh, United States
(author)
-
Zhao, WeiDepartment of Epidemiology, School of Public Health, University of Michigan, MI, Ann Arbor, United States
(author)
-
Zonderman, Alan B.Behavioral Epidemiology Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, MD, Baltimore, United States
(author)
-
Becker, Diane M.Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, MD, Baltimore, United States
(author)
-
Bowden, Donald W.Biochemistry, Wake Forest School of Medicine, NC, Winston-Salem, United States
(author)
-
Deary, Ian J.Department of Psychology, Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, United Kingdom
(author)
-
Dörr, MarcusDZHK (German Centre for Cardiovascular Health), Partner Site Greifswald, Greifswald, Germany; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany
(author)
-
Esko, TõnuEstonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia; Broad Institute of the Massachusetts Institute of Technology and Harvard University, MA, Boston, United States
(author)
-
Freedman, Barry I.Section on Nephrology, Department of Internal Medicine, Wake Forest School of Medicine, Winston-, NC, Salem, United States
(author)
-
Froguel, PhilippeCNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, France; Department of Genomics of Common Disease, Imperial College London, London, United Kingdom
(author)
-
Gasparini, PaoloMedical Genetics, Department of Medicine, Surgery and Health Sciences, University of Trieste, Trieste, Italy; Institute for Maternal and Child Health–IRCCS “Burlo Garofolo”, Trieste, Italy
(author)
-
Gieger, ChristianResearch Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany
(author)
-
Jonas, Jost BrunoDepartment of Ophthalmology, Medical Faculty Mannheim, University Heidelberg, Mannheim, Germany; Beijing Institute of Ophthalmology, Beijing Ophthalmology and Visual Science Key Lab, Beijing Tongren Eye Center, Capital Medical University, Beijing, China
(author)
-
Kammerer, Candace M.Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, PA, Pittsburgh, United States
(author)
-
Kato, NorihiroDepartment of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan
(author)
-
Lakka, Timo A.Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland
(author)
-
Leander, KarinKarolinska Institutet
(author)
-
Lehtimäki, TerhoDepartment of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, University of Tampere, Tampere, Finland
(author)
-
Magnusson, Patrik K. E.Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Stockholm, Sweden
(author)
-
Marques-Vidal, PedroDepartment of Medicine, Internal Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland
(author)
-
Penninx, Brenda W. J. H.Department of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, VU University Medical Center, Amsterdam, Netherlands
(author)
-
Samani, Nilesh J.Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, United Kingdom
(author)
-
van der Harst, PimUniversity of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, Netherlands; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Ultrecht, Netherlands
(author)
-
Wagenknecht, Lynne E.Public Health Sciences, Wake Forest School of Medicine, NC, Winston-Salem, United States
(author)
-
Wu, TangchunDepartment of Occupational and Environmental Health and State Key Laboratory of Environmental Health for Incubating, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
(author)
-
Zheng, WeiDivision of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, TN, Nashville, United States
(author)
-
Zhu, XiaofengDepartment of Population and Quantitative Health Sciences, Case Western Reserve University, OH, Cleveland, United States
(author)
-
Bouchard, ClaudeHuman Genomics Laboratory, Pennington Biomedical Research Center, LA, Baton Rouge, United States
(author)
-
Cooper, Richard S.Department of Public Health Sciences, Loyola University Chicago, IL, Maywood, United States
(author)
-
Correa, AdolfoJackson Heart Study, Department of Medicine, University of Mississippi Medical Center, MS, Jackson, United States
(author)
-
Evans, Michele K.Health Disparities Research Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, MD, Baltimore, United States
(author)
-
Gudnason, VilmundurIcelandic Heart Association, Kopavogur, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, Iceland
(author)
-
Hayward, CarolineMedical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom
(author)
-
Horta, Bernardo L.Postgraduate Programme in Epidemiology, Federal University of Pelotas, RS, Pelotas, Brazil
(author)
-
Kelly, Tanika N.Epidemiology, Tulane University School of Public Health and Tropical Medicine, LA, New Orleans, United States
(author)
-
Kritchevsky, Stephen B.Sticht Center for Health Aging and Alzheimer’s Prevention, Department of Internal Medicine, Wake Forest School of Medicine, NC, Winston-Salem, United States
(author)
-
Levy, DanielNHLBI Framingham Heart Study, MA, Framingham, United States; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, NIH, MD, Bethesda, United States
(author)
-
Palmas, Walter R.Division of General Medicine, Department of Medicine, Columbia University Medical Center, NY, New York, United States
(author)
-
Pereira, A.C.Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, SP, São Paulo, Brazil
(author)
-
Province, Michael M.Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, MO, St. Louis, United States
(author)
-
Psaty, Bruce M.Cardiovascular Health Research Unit, Epidemiology, Medicine and Health Services, University of Washington, WA, Seattle, United States; Kaiser Permanente Washington Health Research Institute, WA, Seattle, United States
(author)
-
Ridker, Paul M.Harvard Medical School, MA, Boston, United States; Brigham and Women’s Hospital, MA, Boston, United States
(author)
-
Rotimi, Charles N.Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, MD, Bethesda, United States
(author)
-
Tai, E. ShyongSaw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore; Health Services and Systems Research, Duke-NUS Medical School, Singapore, Singapore; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
(author)
-
van Dam, Rob M.Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
(author)
-
van Duijn, Cornelia M.Department of Epidemiology, Erasmus University Medical Center, Rotterdam, Netherlands; Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom
(author)
-
Wong, Tien YinOcular Epidemiology, Singapore Eye Research Institute, Singapore National Ecy Centre, Singapore, Singapore; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore
(author)
-
Rice, KennethDepartment of Biostatistics, University of Washington, WA, Seattle, United States
(author)
-
Gauderman, W. JamesBiostatistics, Preventive Medicine, University of Southern California, CA, Los Angeles, United States
(author)
-
Morrison, Alanna C.Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, TX, Houston, United States
(author)
-
North, Kari E.Epidemiology, University of North Carolina Gilling School of Global Public Health, NC, Chapel Hill, United States
(author)
-
Kardia, Sharon L. R.Department of Epidemiology, School of Public Health, University of Michigan, MI, Ann Arbor, United States
(author)
-
Caulfield, Mark J.Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom; NIHR Barts Cardiovascular Biomedical Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, London, United Kingdom
(author)
-
Elliott, PaulDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom; MRC-PHE Centre for Environment and Health, Imperial College London, London, United Kingdom
(author)
-
Munroe, Patricia B.Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom; NIHR Barts Cardiovascular Biomedical Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, London, United Kingdom
(author)
-
Franks, Paul W.Umeå University,Lund University,Lunds universitet,Umeå universitet,Avdelningen för hållbar hälsa,Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Skåne University Hospital, Skåne, Malmö, Sweden,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups(Swepub:lu)med-plf
(author)
-
Rao, Dabeeru C.Division of Biostatistics, Washington University School of Medicine, MO, St. Louis, United States
(author)
-
Fornage, MyriamInstitute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, TX, Houston, United States
(author)
-
Cardiovascular Division, Department of Medicine, Washington University, MO, St. Louis, United States; Division of Biostatistics, Washington University School of Medicine, MO, St. Louis, United StatesDivision of Biostatistics, Washington University School of Medicine, MO, St. Louis, United States
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In:Molecular Psychiatry: Springer Nature26:6, s. 2111-21251359-41841476-5578
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