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Sökning: (WFRF:(Sahebkar Amirhossein)) srt2:(2022) > Step-by-step diagno...

Step-by-step diagnosis and management of the nocebo/drucebo effect in statin-associated muscle symptoms patients : a position paper from the International Lipid Expert Panel (ILEP)

Penson, Peter E. (författare)
School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, United Kingdom; Liverpool Centre for Cardiovascular Science, Liverpool, United Kingdom
Bruckert, Eric (författare)
Pitié-Salpetrière Hospital and Sorbonne University, Cardio metabolic Institute, Paris, France
Marais, David (författare)
Chemical Pathology Division of the Department of Pathology, University of Cape Town Health Science Faculty, Cape Town, South Africa
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Reiner, Željko (författare)
Department of Internal Medicine, University Hospital Centre Zagreb, School of Medicine University of Zagreb, Zagreb, Croatia
Pirro, Matteo (författare)
Department of Medicine, University of Perugia, Perugia, Italy
Sahebkar, Amirhossein (författare)
Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran; Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Clinic of Cardiology, University Clinical Centre of Kosova, Medical Faculty, University of Prishtina, Prishtina,Kosovo
Bajraktari, Gani (författare)
Umeå universitet,Avdelningen för medicin,Department of Internal Disease, Kyrgyz State Medical Academy, Bishkek, Kyrgyzstan
Mirrakhimov, Erkin (författare)
Department of Atherosclerosis and Coronary Heart Disease, National Center of Cardiology and Internal Diseases, Bishkek, Kyrgyzstan
Rizzo, Manfredi (författare)
Department of Health Promotion Sciences Maternal and Infantile Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy; Division of Endocrinology, Diabetes and Metabolism, School of Medicine, University of South Carolina, SC, Columbia, United States
Mikhailidis, Dimitri P. (författare)
Department of Clinical Biochemistry, University College London Medical School, University College London (UCL), London, United Kingdom
Sachinidis, Alexandros (författare)
Department of Health Promotion Sciences Maternal and Infantile Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, Palermo, Italy; 2nd Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece
Gaita, Dan (författare)
Universitatea de Medicina si Farmacie Victor Babes, Timisoara, Romania; Clinica de Cardiologie, Institutul de Boli Cardiovasculare Timisoara, Timisoara, Romania
Latkovskis, Gustavs (författare)
Pauls Stradins Clinical University Hospital, Riga, Latvia; University of Latvia, Riga, Latvia
Mazidi, Mohsen (författare)
Medical Research Council Population Health Research Unit, University of Oxford, Oxford, United Kingdom; Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom
Toth, Peter P. (författare)
CGH Medical Center, IL, Sterling, United States; Cicarrone Center for the Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, MD, Baltimore, United States
Pella, Daniel (författare)
2nd Department of Cardiology of the East Slovak Institute of Cardiovascular Disease and Faculty of Medicine, PJ Safarik University, Kosice, Slovakia
Alnouri, Fahad (författare)
Cardiovascular Prevention Unit, Adult Cardiology Department, Prince Sultan Cardiac Centre Riyadh, Riyadh, Saudi Arabia
Postadzhiyan, Arman (författare)
Department of General Medicine, Emergency University Hospital ‘St. Anna’, Medical University of Sofia, Sofia, Bulgaria
Yeh, Hung-I (författare)
Department of Medicine, MacKay Medical College, New Taipei City, Taiwan
Mancini, G.B. John (författare)
Department of General Medicine, Emergency University Hospital ‘St. Anna’, Medical University of Sofia, Sofia, Bulgaria
von Haehling, Stephan (författare)
Department of Cardiology and Pneumology, Heart Center, University of Göttingen Medical Center, Göttingen, Germany; German Center for Cardiovascular Research (DZHK), partner site Göttingen, Göttingen, Germany
Banach, Maciej (författare)
Polish Moother's Memorial Hospital Research Institute (PMMHRI), Lodz, Poland; Department of Preventive Cardiology and Lipidology, Medical University of Lodz (MUL), Lodz, Poland; Cardiovascular Research Centre, University of Zielona Gora, Zielona Gora, Poland
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 (creator_code:org_t)
2022-03-10
2022
Engelska.
Ingår i: Journal of Cachexia, Sarcopenia and Muscle. - : John Wiley & Sons. - 2190-5991 .- 2190-6009. ; 13:3, s. 1596-1622
  • Forskningsöversikt (refereegranskat)
Abstract Ämnesord
Stäng  
  • Statin intolerance is a clinical syndrome whereby adverse effects (AEs) associated with statin therapy [most commonly statin-associated muscle symptoms (SAMS)] result in the discontinuation of therapy and consequently increase the risk of adverse cardiovascular outcomes. However, complete statin intolerance occurs in only a small minority of treated patients (estimated prevalence of only 3–5%). Many perceived AEs are misattributed (e.g. physical musculoskeletal injury and inflammatory myopathies), and subjective symptoms occur as a result of the fact that patients expect them to do so when taking medicines (the nocebo/drucebo effect)—what might be truth even for over 50% of all patients with muscle weakness/pain. Clear guidance is necessary to enable the optimal management of plasma in real-world clinical practice in patients who experience subjective AEs. In this Position Paper of the International Lipid Expert Panel (ILEP), we present a step-by-step patient-centred approach to the identification and management of SAMS with a particular focus on strategies to prevent and manage the nocebo/drucebo effect and to improve long-term compliance with lipid-lowering therapy.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

Nyckelord

Drucebo effect
Nocebo effect
SAMS
Statin intolerance

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