Search: WFRF:(Andersson Linnea) >
Early-life risk fac...
Early-life risk factors for development of asthma from 8 to 28 years of age : a prospective cohort study
-
- Hedman, Linnea, 1979- (author)
- Umeå universitet,Avdelningen för hållbar hälsa
-
- Almqvist, Linnea (author)
- Umeå universitet,Avdelningen för hållbar hälsa
-
- Bjerg, Anders (author)
- Martina Children’s Hospital, Stockholm, Sweden
-
show more...
-
- Andersson, Martin (author)
- Umeå universitet,Avdelningen för hållbar hälsa
-
- Backman, Helena (author)
- Umeå universitet,Avdelningen för hållbar hälsa
-
- Perzanowski, Matthew S. (author)
- Dept of Environmental Health Sciences, Mailman School of Public Health, Columbia University, NY, New York, United States
-
- Rönmark, Eva (author)
- Umeå universitet,Avdelningen för hållbar hälsa
-
show less...
-
(creator_code:org_t)
- 2022-06-30
- 2022
- English.
-
In: ERJ Open Research. - : European Respiratory Society. - 2312-0541. ; 8:4
- Related links:
-
https://doi.org/10.1...
-
show more...
-
https://umu.diva-por... (primary) (Raw object)
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- Background: The objective was to estimate the incidence rate of asthma from age 8 to 28 years and evaluate early-life risk factors for asthma onset at different ages.Methods: In 1996, within the Obstructive Lung Disease in Northern Sweden (OLIN) studies, a cohort of 3430 schoolchildren (97% of invited) was recruited at age 8 years to a prospective study about asthma. The cohort was followed annually from age 8 to 19 years and at 28 years by questionnaire surveys (67% of the original cohort participated). Asthma was categorised as never-asthma, onset age ⩽8 years, onset age 9–13 years, onset age 14–19 years or onset age >19 years.Results: Of the 3430 individuals in the cohort, 690 (20.1%) reported asthma in any survey. The average incidence rate was 10.0/1000 per year at ⩽8 years, 11.9/1000 per year at 9–13 years, 13.3/1000 per year at 14–19 years and 6.1/1000 per year at >19 years. The incidence was higher among boys until age 10 years, but from age 15 years, it became higher among girls. Family history of asthma, allergic sensitisation and breastfeeding <3 months were associated with asthma onset throughout the study. Low birthweight, maternal smoking during pregnancy, severe respiratory infection, rhinoconjunctivitis and eczema were associated with asthma onset ⩽8 and 9–13 years.Conclusions: The incidence of asthma was high during childhood and the teenage period, and decreased substantially during young adulthood. Early-life factors were associated with asthma onset throughout childhood but had also a lasting effect on asthma incidence until adulthood.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database