Search: WFRF:(Freisling Heinz) >
Dietary intake of t...
-
Aglago, Elom K.Nutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom,International Agency for Research on Cancer, World Health Organization
(author)
Dietary intake of total, heme and non-heme iron and the risk of colorectal cancer in a European prospective cohort study
- Article/chapterEnglish2023
Publisher, publication year, extent ...
-
2023-02-09
-
Springer Nature,2023
-
printrdacarrier
Numbers
-
LIBRIS-ID:oai:DiVA.org:umu-204992
-
https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-204992URI
-
https://doi.org/10.1038/s41416-023-02164-7DOI
-
https://lup.lub.lu.se/record/1fbd04cf-a8ec-4a65-8b53-54e70b0708fdURI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:ref swepub-contenttype
-
Subject category:art swepub-publicationtype
Notes
-
Background: Iron is an essential micronutrient with differing intake patterns and metabolism between men and women. Epidemiologic evidence on the association of dietary iron and its heme and non-heme components with colorectal cancer (CRC) development is inconclusive.Methods: We examined baseline dietary questionnaire-assessed intakes of total, heme, and non-heme iron and CRC risk in the EPIC cohort. Sex-specific multivariable-adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) were computed using Cox regression. We modelled substitution of a 1 mg/day of heme iron intake with non-heme iron using the leave one-out method.Results: Of 450,105 participants (318,680 women) followed for 14.2 ± 4.0 years, 6162 (3511 women) developed CRC. In men, total iron intake was not associated with CRC risk (highest vs. lowest quintile, HRQ5vs.Q1:0.88; 95%CI:0.73, 1.06). An inverse association was observed for non-heme iron (HRQ5vs.Q1:0.80, 95%CI:0.67, 0.96) whereas heme iron showed a non-significant association (HRQ5vs.Q1:1.10; 95%CI:0.96, 1.27). In women, CRC risk was not associated with intakes of total (HRQ5vs.Q1:1.11, 95%CI:0.94, 1.31), heme (HRQ5vs.Q1:0.95; 95%CI:0.84, 1.07) or non-heme iron (HRQ5vs.Q1:1.03, 95%CI:0.88, 1.20). Substitution of heme with non-heme iron demonstrated lower CRC risk in men (HR:0.94; 95%CI: 0.89, 0.99).Conclusions: Our findings suggest potential sex-specific CRC risk associations for higher iron consumption that may differ by dietary sources.
Subject headings and genre
Added entries (persons, corporate bodies, meetings, titles ...)
-
Cross, Amanda J.Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom,International Agency for Research on Cancer, World Health Organization
(author)
-
Riboli, ElioDepartment of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom
(author)
-
Fedirko, VeronikaDepartment of Epidemiology, University of Texas M. D. Anderson Cancer Center, TX, Houston, United States; Department of Epidemiology, Rollins School of Public Health, Emory University, GA, Atlanta, United States
(author)
-
Hughes, David J.Cancer Biology and Therapeutics Group (CBT), Conway Institute, School of Biomolecular and Biomedical Science (SBBS), University College Dublin, Dublin, Ireland
(author)
-
Fournier, AgnesCentre de Recherche en Epidémiologie et Santé des Populations, Université Paris-Sud, UVSQ, INSERM, Université Paris-Saclay, Villejuif, France; Institut Gustave Roussy, Villejuif, France
(author)
-
Jakszyn, PaulaUnit of Nutrition and Cancer, Cancer Epidemiology Research Programme, Catalan Institute of Oncology (ICO-IDIBELL), Barcelona, Spain; Blanquerna School of Health Sciences, Ramon Llull University, Barcelona, Spain
(author)
-
Freisling, HeinzNutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France,International Agency for Research on Cancer, World Health Organization
(author)
-
Gunter, Marc J.Nutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France,International Agency for Research on Cancer, World Health Organization
(author)
-
Dahm, Christina C.Department of Public Health, Aarhus University, Aarhus, Denmark,International Agency for Research on Cancer, World Health Organization
(author)
-
Overvad, KimDepartment of Public Health, Aarhus University, Aarhus, Denmark; Department of Cardiology, Aalborg University Hospital, Aalborg, Denmark
(author)
-
Tjønneland, AnneDanish Cancer Society Research Center, Copenhagen, Denmark; Department of Public Health, Section of Environmental Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
(author)
-
Kyrø, CecilieDanish Cancer Society Research Center, Copenhagen, Denmark
(author)
-
Boutron-Ruault, Marie-ChristineCentre de Recherche en Epidémiologie et Santé des Populations, Université Paris-Sud, UVSQ, INSERM, Université Paris-Saclay, Villejuif, France; Institut Gustave Roussy, Villejuif, France
(author)
-
Rothwell, Joseph A.Centre de Recherche en Epidémiologie et Santé des Populations, Université Paris-Sud, UVSQ, INSERM, Université Paris-Saclay, Villejuif, France; Institut Gustave Roussy, Villejuif, France
(author)
-
Severi, GianlucaCentre de Recherche en Epidémiologie et Santé des Populations, Université Paris-Sud, UVSQ, INSERM, Université Paris-Saclay, Villejuif, France; Institut Gustave Roussy, Villejuif, France; Department of Statistics, Computer Science, Applications “G. Parenti”, University of Florence, Florence, Italy
(author)
-
Katzke, VerenaDivision of Cancer Epidemiology, German Cancer research Center (DKFZ), Heidelberg, Germany
(author)
-
Srour, BernardDivision of Cancer Epidemiology, German Cancer research Center (DKFZ), Heidelberg, Germany
(author)
-
Schulze, Matthias B.Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany; Institute of Nutritional Science, University of Potsdam, Potsdam, Germany
(author)
-
Wittenbecher, ClemensDepartment of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany; Department of Nutrition, Harvard T.H. Chan School of Public Health, MA, Boston, United States; German Center for Diabetes Research (DZD), Neuherberg, Germany,Harvard University
(author)
-
Palli, DomenicoCancer Risk Factors and Life-Style Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network, ISPRO, Florence, Italy
(author)
-
Sieri, SabinaEpidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Via Venezian, Milano, Italy
(author)
-
Pasanisi, FabrizioInternal Medicine and Clinical Nutrition Unit, Department of Clinical Medicine and Surgery, Federico II University Hospital, Naples, Italy,Azienda Ospedaliera Universitaria Federico II
(author)
-
Tumino, RosarioHyblean Association for Epidemiological Research, AIRE-ONLUS, Ragusa, Italy
(author)
-
Ricceri, FulvioDepartment of Clinical and Biological Sciences, University of Turin, Turin, Italy; Unit of Epidemiology, Regional Health Service, TO, Grugliasco, Italy
(author)
-
Bueno-de-Mesquita, BasFormer senior scientist, Department for Determinants of Chronic Diseases (DCD), National Institute for Public Health and the Environment (RIVM), PO Box 1, Bilthoven, Netherlands
(author)
-
Derksen, Jeroen W. G.Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands
(author)
-
Skeie, GuriFaculty of Health Sciences, Department of Community Medicine, University of Tromsø, The Arctic University of Norway, Tromsø, Norway,UiT The Arctic University of Norway, Tromsø
(author)
-
Jensen, Torill EngetFaculty of Health Sciences, Department of Community Medicine, University of Tromsø, The Arctic University of Norway, Tromsø, Norway,UiT The Arctic University of Norway, Tromsø
(author)
-
Lukic, MarkoFaculty of Health Sciences, Department of Community Medicine, University of Tromsø, The Arctic University of Norway, Tromsø, Norway,UiT The Arctic University of Norway, Tromsø
(author)
-
Sánchez, Maria-JoseEscuela Andaluza de Salud Pública (EASP), Granada, Spain; Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain; Department of Preventive Medicine and Public Health, University of Granada, Granada, Spain; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain,CIBER Epidemiology and Public Health (CIBERESP),Andalusian School Of Public Health (EASP)
(author)
-
Amiano, PilarCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain; Ministry of Health of the Basque Government, Sub-Directorate for Public Health and Addictions of Gipuzkoa, San Sebastián, Spain; Biodonostia Health Research Institute, Epidemiology and Public Health Area, San Sebastián, Spain,CIBER Epidemiology and Public Health (CIBERESP)
(author)
-
Colorado-Yohar, SandraCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain; Department of Epidemiology, Murcia Regional Health Council, IMIB-Arrixaca, Murcia, Spain; Research Group on Demography and Health, National Faculty of Public Health, University of Antioquia, Medellín, Colombia,CIBER Epidemiology and Public Health (CIBERESP)
(author)
-
Barricarte, AurelioCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain; Navarra Public Health Institute, Pamplona, Spain; Navarra Institute for Health Research (IdiSNA), Pamplona, Spain,CIBER Epidemiology and Public Health (CIBERESP)
(author)
-
Ericson, UlrikaLund University,Lunds universitet,Diabetes - kardiovaskulär sjukdom,Forskargrupper vid Lunds universitet,Diabetes - Cardiovascular Disease,Lund University Research Groups(Swepub:lu)medf-upe
(author)
-
van Guelpen, BethanyUmeå University,Umeå universitet,Institutionen för strålningsvetenskaper,Wallenberg centrum för molekylär medicin vid Umeå universitet (WCMM)(Swepub:umu)beyvan99
(author)
-
Papier, KerenCancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom
(author)
-
Knuppel, AnikaCancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom
(author)
-
Casagrande, CorinneNutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France
(author)
-
Huybrechts, IngeNutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France,International Agency for Research on Cancer, World Health Organization
(author)
-
Heath, Alicia K.Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom
(author)
-
Tsilidis, Konstantinos K.Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom
(author)
-
Jenab, MazdaNutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France
(author)
-
Nutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United KingdomInternational Agency for Research on Cancer, World Health Organization
(creator_code:org_t)
Related titles
-
In:British Journal of Cancer: Springer Nature128, s. 1529-15400007-09201532-1827
Internet link
Find in a library
To the university's database
- By the author/editor
-
Aglago, Elom K.
-
Cross, Amanda J.
-
Riboli, Elio
-
Fedirko, Veronik ...
-
Hughes, David J.
-
Fournier, Agnes
-
show more...
-
Jakszyn, Paula
-
Freisling, Heinz
-
Gunter, Marc J.
-
Dahm, Christina ...
-
Overvad, Kim
-
Tjønneland, Anne
-
Kyrø, Cecilie
-
Boutron-Ruault, ...
-
Rothwell, Joseph ...
-
Severi, Gianluca
-
Katzke, Verena
-
Srour, Bernard
-
Schulze, Matthia ...
-
Wittenbecher, Cl ...
-
Palli, Domenico
-
Sieri, Sabina
-
Pasanisi, Fabriz ...
-
Tumino, Rosario
-
Ricceri, Fulvio
-
Bueno-de-Mesquit ...
-
Derksen, Jeroen ...
-
Skeie, Guri
-
Jensen, Torill E ...
-
Lukic, Marko
-
Sánchez, Maria-J ...
-
Amiano, Pilar
-
Colorado-Yohar, ...
-
Barricarte, Aure ...
-
Ericson, Ulrika
-
van Guelpen, Bet ...
-
Papier, Keren
-
Knuppel, Anika
-
Casagrande, Cori ...
-
Huybrechts, Inge
-
Heath, Alicia K.
-
Tsilidis, Konsta ...
-
Jenab, Mazda
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Cancer and Oncol ...
- Articles in the publication
-
British Journal ...
- By the university
-
Umeå University
-
Lund University