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Sökning: onr:"swepub:oai:DiVA.org:umu-206768" > Determining impairm...

  • Finsel, JuliaDepartment of Neurology, Ulm University, Ulm, Germany (författare)

Determining impairment in the Swedish, Polish and German ECAS : the importance of adjusting for age and education

  • Artikel/kapitelEngelska2023

Förlag, utgivningsår, omfång ...

  • 2023-03-30
  • Taylor & Francis,2023
  • electronicrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:umu-206768
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-206768URI
  • https://doi.org/10.1080/21678421.2023.2192248DOI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Objective: Age and years of education are strong predictors of cognitive performance in several versions of the Edinburgh Cognitive and Behavioral ALS Screen (ECAS) and cutoffs for the Swedish and Polish versions are not established yet. Here we evaluated the performance of healthy subjects on the national versions of the Swedish and Polish ECAS and compared cognitive performance on three European translations of the ECAS.Methods: The ECAS performances of healthy subjects from Sweden (n = 111), Poland (n = 124) and Germany (n = 86) were compared. Based on the test results on the national versions of ECAS, age- and education-adjusted cutoffs were compared for the German, Swedish and Polish versions, respectively.Results: Age and years of education correlated with performance in the ECAS. Swedish subjects under the age of 60 years and Swedish subjects with low education level scored significantly higher in memory than the respective German and Polish subgroups. German and Polish subjects over 60 years of age performed significantly better in language than the respective Swedish subgroup. The Polish cohort in total had lower executive scores compared to the Swedish cohort, and lower than the German subjects in the higher education subgroup.Conclusions: The results highlight the importance of establishing age- and education-adjusted ECAS cutoffs not only in general, but also for seemingly similar populations of different origins. The results should be taken into account when comparing cognition data across patient populations including in drug trials where an ECAS test result is being used as an inclusion criterium or outcome measure.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Winroth, IvarUmeå universitet,Neurovetenskaper(Swepub:umu)ivwi0001 (författare)
  • Ciećwierska, KatarzynaDepartment of Neurology, University Clinical Centre of Medical University of Warsaw, Warsaw, Poland (författare)
  • Helczyk, OlgaDepartment of Neurology, Ulm University, Ulm, Germany (författare)
  • Stenberg, Erica A.Umeå universitet,Neurovetenskaper(Swepub:umu)eral0022 (författare)
  • Häggström, Ann-CristinUmeå universitet,Neurovetenskaper(Swepub:umu)anha0123 (författare)
  • Ludolph, Albert C.Department of Neurology, Ulm University, Ulm, Germany (författare)
  • Uttner, IngoDepartment of Neurology, Ulm University, Ulm, Germany (författare)
  • Semb, OlofUmeå universitet,Psykiatri(Swepub:umu)olse0001 (författare)
  • Pilczuk, BeataDepartment of Neurology, University Clinical Centre of Medical University of Warsaw, Warsaw, Poland (författare)
  • Szejko, NataliaDepartment of Neurology, University Clinical Centre of Medical University of Warsaw, Warsaw, Poland; Department of Bioethics, Medical University of Warsaw, Warsaw, Poland (författare)
  • Rosentul, Simona (författare)
  • Lulé, DorothéeDepartment of Neurology, Ulm University, Ulm, Germany (författare)
  • Kuźma-Kozakiewicz, MagdalenaDepartment of Neurology, University Clinical Centre of Medical University of Warsaw, Warsaw, Poland; Department of Neurology, Medical University of Warsaw, Warsaw, Poland; Neurodegenerative Diseases Research Group, Medical University of Warsaw, Warsaw, Poland (författare)
  • Andersen, Peter M.,1962-Umeå universitet,Neurovetenskaper(Swepub:umu)pean0001 (författare)
  • Department of Neurology, Ulm University, Ulm, GermanyNeurovetenskaper (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration: Taylor & Francis24:5-6, s. 475-4842167-84212167-9223

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