CSF drainage

• In an early retrospective study in 39 patients, intermittent or continuous CSF drainage was applied, and it was concluded that early drainage was of little use in influencing ICP while later CSF removal had a more pronounced effect (Papo et al. 1981). In a prospective study on 31 patients, it was shown that various volumes of CSF intermittent drainage significantly decreased the ICP with a few mmHg, but in only 6/31 subjects, the decrease was more than 3 mmHg and lasting for more than 10 min (Kerr et al. 2000). A prospective study in 24 subjects, with sustained elevated ICP after other ICP decreasing measures, showed that in about 50% of the cases, the ICP was brought under control after continuous drainage (Timofeev et al. 2008). In a prospective study of 45 patients with sTBI and 55 patients with SAH and presenting refractory ICP elevation, a combination of ventriculostomy and lumbar drainage was shown to reduce the ICP but not to affect outcome (Tuettenberg et al. 2009). In that same study, 12% presented with cerebral herniation and 6% died due to herniation. Some studies have shown an improved outcome after using CSF drainage (Timofeev et al. 2008; Ghajar et al. 1993).

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Neurologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Neurology (hsv//eng)

Publication and Content Type

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