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Drinking alcohol in moderation is associated with lower rate of all-cause mortality in individuals with higher rather than lower educational level : findings from the MORGAM project
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- Di Castelnuovo, Augusto (författare)
- Mediterranea Cardiocentro, Naples, Italy
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- Bonaccio, Marialaura (författare)
- Department of Epidemiology and Prevention, IRCCS NEUROMED, IS, Pozzilli, Italy
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- Costanzo, Simona (författare)
- Department of Epidemiology and Prevention, IRCCS NEUROMED, IS, Pozzilli, Italy
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- McElduff, Patrick (författare)
- Hunter Medical Research Institute, University of Newcastle, Newcastle, Australia
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- Linneberg, Allen (författare)
- Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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- Salomaa, Veikko (författare)
- Finnish Institute for Health and Welfare, Helsinki, Finland
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- Männistö, Satu (författare)
- Finnish Institute for Health and Welfare, Helsinki, Finland
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- Ferrières, Jean (författare)
- Department of Cardiology and INSERM UMR 1295, Toulouse University Hospital, Toulouse, France
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- Dallongeville, Jean (författare)
- Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1167 - RID-AGE, Lille, France
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- Thorand, Barbara (författare)
- Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany
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- Brenner, Hermann (författare)
- Division of Clinical Epidemiology and Aging Research and Division of Preventive Oncology, German Cancer Research Center, Heidelberg, Germany
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- Ferrario, Marco (författare)
- Department of Medicine and Surgery, Research Center in Epidemiology and Preventive Medicine (EPIMED), University of Insubria, Varese, Italy
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- Veronesi, Giovanni (författare)
- Department of Medicine and Surgery, Research Center in Epidemiology and Preventive Medicine (EPIMED), University of Insubria, Varese, Italy
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- Tamosiunas, Abdonas (författare)
- Lithuanian University of Health Sciences, Kaunas, Lithuania
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- Grimsgaard, Sameline (författare)
- Department of Community Medicine, Faculty of Health Sciences, UiT the Arctic University of Norway, Tromsø, Norway
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- Drygas, Wojciech (författare)
- Department of Epidemiology CVD Prevention and Health Promotion, National Institute of Cardiology, Warsaw, Poland; Calisia University, Kalisz, Poland
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- Malyutina, Sofia (författare)
- The Institute of Internal and Preventive Medicine -Branch of the “FRC Institute of Cytology and Genetics SB RAS”, Novosibirsk, Russian Federation
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- Söderberg, Stefan (författare)
- Umeå universitet,Institutionen för folkhälsa och klinisk medicin
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- Nordendahl, Maria (författare)
- Umeå universitet,Institutionen för folkhälsa och klinisk medicin
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- Kee, Frank (författare)
- Centre for Public Health, Queens University of Belfast, Belfast, United Kingdom
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- Grassi, Guido (författare)
- Clinica Medica, Università Milano-Bicocca, Milan, Italy
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- Dabboura, Salim (författare)
- Clinic of General and Interventional Cardiology, University Heart & Vascular Center Hamburg, Germany, and German Center for Cardiovascular Research, partner site Hamburg/Lübeck/Kiel, Hamburg, Germany
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- Borchini, Rossana (författare)
- Occupational and Preventive Medicine, ASST Lariana, Como, Italy
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- Westermann, Dirk (författare)
- Department for Cardiology and Angiology, Medical Faculty of Medicine, University Heart Center Freiburg-Bad Krozingen, University of Freiburg, Freiburg, Germany
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- Schrage, Benedikt (författare)
- Clinic of General and Interventional Cardiology, University Heart & Vascular Center Hamburg, Germany, and German Center for Cardiovascular Research, partner site Hamburg/Lübeck/Kiel, Hamburg, Germany
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- Zeller, Tanja (författare)
- Clinic of General and Interventional Cardiology, University Heart & Vascular Center Hamburg, Germany, and German Center for Cardiovascular Research, partner site Hamburg/Lübeck/Kiel, Hamburg, Germany
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- Kuulasmaa, Kari (författare)
- Finnish Institute for Health and Welfare, Helsinki, Finland
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- Blankenberg, Stefan (författare)
- Clinic of General and Interventional Cardiology, University Heart & Vascular Center Hamburg, Germany, and German Center for Cardiovascular Research, partner site Hamburg/Lübeck/Kiel, Hamburg, Germany
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- Donati, Maria Benedetta (författare)
- Department of Epidemiology and Prevention, IRCCS NEUROMED, IS, Pozzilli, Italy
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- Iacoviello, Licia (författare)
- Department of Epidemiology and Prevention, IRCCS NEUROMED, IS, Pozzilli, Italy; Department of Medicine and Surgery, Research Center in Epidemiology and Preventive Medicine (EPIMED), University of Insubria, Varese, Italy
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- de Gaetano, Giovanni (författare)
- Department of Epidemiology and Prevention, IRCCS NEUROMED, IS, Pozzilli, Italy
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(creator_code:org_t)
- Springer Nature, 2023
- 2023
- Engelska.
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Ingår i: European Journal of Epidemiology. - : Springer Nature. - 0393-2990 .- 1573-7284. ; 38:8, s. 869-881
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- The association between socioeconomic status (SES) and alcohol-related diseases has been widely explored. Less is known, however, on whether the association of moderate drinking with all-cause mortality is modified by educational level (EL). Using harmonized data from 16 cohorts in the MORGAM Project (N = 142,066) the association of pattern of alcohol intake with hazard of all-cause mortality across EL (lower = primary-school; middle = secondary-school; higher = university/college degree) was assessed using multivariable Cox-regression and spline curves. A total of 16,695 deaths occurred in 11.8 years (median). In comparison with life-long abstainers, participants drinking 0.1–10 g/d of ethanol had 13% (HR = 0.87; 95%CI: 0.74–1.02), 11% (HR = 0.89; 0.84–0.95) and 5% (HR = 0.95; 0.89–1.02) lower rate of death in higher, middle and lower EL, respectively. Conversely, drinkers > 20 g/d had 1% (HR = 1.01; 0.82–1.25), 10% (HR = 1.10; 1.02–1.19) and 17% (HR = 1.17; 1.09–1.26) higher rate of death. The association of alcohol consumption with all-cause mortality was nonlinear, with a different J-shape by EL levels. It was consistent across both sexes and in various approaches of measuring alcohol consumption, including combining quantity and frequency and it was more evident when the beverage of preference was wine. We observed that drinking in moderation (≤ 10 g/d) is associated with lower mortality rate more evidently in individuals with higher EL than in people with lower EL, while heavy drinking is associated with higher mortality rate more evidently in individuals with lower EL than in people with higher EL, suggesting that advice on reducing alcohol intake should especially target individuals of low EL.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- Alcohol
- All-cause mortality
- Educational levels
- Social status
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Di Castelnuovo, ...
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Bonaccio, Marial ...
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Costanzo, Simona
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McElduff, Patric ...
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Linneberg, Allen
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Salomaa, Veikko
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visa fler...
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Männistö, Satu
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Ferrières, Jean
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Dallongeville, J ...
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Thorand, Barbara
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Brenner, Hermann
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Ferrario, Marco
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Veronesi, Giovan ...
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Tamosiunas, Abdo ...
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Grimsgaard, Same ...
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Drygas, Wojciech
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Malyutina, Sofia
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Söderberg, Stefa ...
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Nordendahl, Mari ...
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Kee, Frank
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Grassi, Guido
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Dabboura, Salim
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Borchini, Rossan ...
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Westermann, Dirk
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Schrage, Benedik ...
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Zeller, Tanja
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Kuulasmaa, Kari
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Blankenberg, Ste ...
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Donati, Maria Be ...
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Iacoviello, Lici ...
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de Gaetano, Giov ...
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