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Tricuspid regurgita...
Tricuspid regurgitation velocity and mean pressure gradient for the prediction of pulmonary hypertension according to the new hemodynamic definition
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- Mandoli, Giulia Elena (författare)
- Umeå universitet,Institutionen för folkhälsa och klinisk medicin,Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy
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- Landra, Federico (författare)
- Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy
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- Chiantini, Benedetta (författare)
- Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy
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- Sciaccaluga, Carlotta (författare)
- Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy
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- Pastore, Maria Concetta (författare)
- Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy
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- Focardi, Marta (författare)
- Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy
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- Cavigli, Luna (författare)
- Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy
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- D’Ascenzi, Flavio (författare)
- Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy
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- Bernazzali, Sonia (författare)
- Department of Cardiac Surgery, University of Siena, Siena, Italy
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- Maccherini, Massimo (författare)
- Department of Cardiac Surgery, University of Siena, Siena, Italy
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- Valente, Serafina (författare)
- Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy
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- Cameli, Matteo (författare)
- Department of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy
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- Henein, Michael Y. (författare)
- Umeå universitet,Institutionen för folkhälsa och klinisk medicin
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(creator_code:org_t)
- MDPI, 2023
- 2023
- Engelska.
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Ingår i: Diagnostics. - : MDPI. - 2075-4418. ; 13:16
- Relaterad länk:
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https://doi.org/10.3...
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https://umu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.3...
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Abstract
Ämnesord
Stäng
- Background: The hemodynamic definition of PH has recently been revised with unchanged threshold of peak tricuspid regurgitation velocity (TRV). The aim of this study was to evaluate the predictive accuracy of peak TRV for PH based on the new (>20 mmHg) and the old (>25 mmHg) cut-off value for mean pulmonary artery pressure (mPAP) and to compare it with the mean right ventricular–right atrial (RV–RA) pressure gradient. Methods: Patients with advanced heart failure were screened from 2016 to 2021. The exclusion criteria were absent right heart catheterization (RHC) results, chronic obstructive pulmonary disease, any septal defect, inadequate acoustic window or undetectable TR. The mean RV–RA gradient was calculated from the velocity–time integral of TR. Results: The study included 41 patients; 34 (82.9%) had mPAP > 20 mmHg and 24 (58.5%) had mPAP > 25 mmHg. The AUC for the prediction of PH with mPAP > 20 mmHg was 0.855 for peak TRV and mean RV–RA gradient was 0.811. AUC for the prediction of PH defined as mPAP > 25 mmHg for peak TRV was 0.860 and for mean RV–RA gradient was 0.830. A cutoff value of 2.4 m/s for peak TRV had 65% sensitivity and 100% positive predictive value for predicting PH according to the new definition. Conclusions: Peak TRV performed better than mean RV–RA pressure gradient in predicting PH irrespective of hemodynamic definitions. Peak TRV performed similarly with the two definitions of PH, but a lower cutoff value had higher sensitivity and equal positive predictive value for PH.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- echocardiography
- pulmonary hypertension
- right heart catheterization
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Mandoli, Giulia ...
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Landra, Federico
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Chiantini, Bened ...
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Sciaccaluga, Car ...
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Pastore, Maria C ...
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Focardi, Marta
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visa fler...
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Cavigli, Luna
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D’Ascenzi, Flavi ...
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Bernazzali, Soni ...
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Maccherini, Mass ...
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Valente, Serafin ...
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Cameli, Matteo
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Henein, Michael ...
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visa färre...
- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Kardiologi
- Artiklar i publikationen
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Diagnostics
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Umeå universitet