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  • Skovgaard Svingel, LiseDepartment of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University Hospital and Aarhus University, Denmark (författare)

Labor market affiliation of patients with myeloproliferative neoplasms : a population-based matched cohort study

  • Artikel/kapitelEngelska2023

Förlag, utgivningsår, omfång ...

  • 2023
  • Taylor & Francis,2023
  • printrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:umu-214128
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-214128URI
  • https://doi.org/10.1080/0284186x.2023.2251670DOI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

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Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Background: Patients with myeloproliferative neoplasms (MPNs) suffer from substantial symptoms and risk of debilitating complications, yet observational data on their labor market affiliation are scarce.Material and methods: We conducted a descriptive cohort study using data from Danish nationwide registries, including patients diagnosed with MPN in 2010-2016. Each patient was matched with up to ten comparators without MPN on age, sex, level of education, and region of residence. We assessed pre- and post-diagnosis labor market affiliation, defined as working, unemployed, or receiving sickness benefit, disability pension, retirement pension, or other health-related benefits. Labor market affiliation was assessed weekly from two years pre-diagnosis until death, emigration, or 31 December 2018. For patients and comparators, we reported percentage point (pp) changes in labor market affiliation cross-sectionally from week −104 pre-diagnosis to week 104 post-diagnosis.Results: The study included 3,342 patients with MPN and 32,737 comparators. From two years pre-diagnosis until two years post-diagnosis, a larger reduction in the proportion working was observed among patients than comparators (essential thrombocythemia: 10.2 [95% CI: 6.3–14.1] vs. 6.8 [95% CI: 5.5–8.0] pp; polycythemia vera: 9.6 [95% CI: 5.9–13.2] vs. 7.4 [95% CI: 6.2–8.7] pp; myelofibrosis: 8.1 [95% CI: 3.0–13.2] vs. 5.8 [95% CI: 4.2–7.5] pp; and unclassifiable MPN: 8.0 [95% CI: 3.0–13.0] vs. 7.4 [95% CI: 5.7–9.1] pp). Correspondingly, an increase in the proportion of patients receiving sickness benefits including other health-related benefits was evident around the time of diagnosis.Conclusion: Overall, we found that Danish patients with essential thrombocythemia, polycythemia vera, myelofibrosis, and unclassifiable MPN had slightly impaired labor market affiliation compared with a population of the same age and sex. From two years pre-diagnosis to two years post-diagnosis, we observed a larger reduction in the proportion of patients with MPN working and a greater proportion receiving sickness benefits compared with matched individuals.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Friis Christensen, SarahDepartment of Hematology, Zealand University Hospital, Denmark (författare)
  • Kjærsgaard, AndersDepartment of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University Hospital and Aarhus University, Denmark (författare)
  • Stenling, AnnaNovartis Sverige AB, Sweden(Swepub:umu)anabei01 (författare)
  • Paulsson, BjörnNovartis Sverige AB, Sweden (författare)
  • Andersen, Christen LykkegaardDepartment of Hematology, Copenhagen University Hospital, Rigshospitalet, Denmark (författare)
  • Christiansen, Christian FynboDepartment of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University Hospital and Aarhus University, Denmark (författare)
  • Stentoft, JesperDepartment of Hematology, Aarhus University Hospital, Denmark (författare)
  • Starklint, JørnDepartment of Medicine, Goedstrup Hospital, Denmark (författare)
  • Severinsen, Marianne TangDepartment of Hematology, Aalborg University Hospital, Denmark (författare)
  • Borg Clausen, MetteDepartment of Hematology, Copenhagen University Hospital, Rigshospitalet, Denmark (författare)
  • Hagemann Hilsøe, MortenDepartment of Hematology, Hospital of South West Jutland, Denmark (författare)
  • Hasselbalch, Hans CarlDepartment of Hematology, Zealand University Hospital, Denmark (författare)
  • Frederiksen, HenrikDepartment of Hematology, Odense University Hospital, Denmark (författare)
  • Bak, MarieDepartment of Hematology, Zealand University Hospital, Denmark (författare)
  • Mikkelsen, Ellen MargretheDepartment of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University Hospital and Aarhus University, Denmark (författare)
  • Department of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University Hospital and Aarhus University, DenmarkDepartment of Hematology, Zealand University Hospital, Denmark (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Acta Oncologica: Taylor & Francis0284-186X1651-226X

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