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Labor market affili...
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Skovgaard Svingel, LiseDepartment of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University Hospital and Aarhus University, Denmark
(författare)
Labor market affiliation of patients with myeloproliferative neoplasms : a population-based matched cohort study
- Artikel/kapitelEngelska2023
Förlag, utgivningsår, omfång ...
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2023
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Taylor & Francis,2023
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printrdacarrier
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LIBRIS-ID:oai:DiVA.org:umu-214128
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-214128URI
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https://doi.org/10.1080/0284186x.2023.2251670DOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:art swepub-publicationtype
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Background: Patients with myeloproliferative neoplasms (MPNs) suffer from substantial symptoms and risk of debilitating complications, yet observational data on their labor market affiliation are scarce.Material and methods: We conducted a descriptive cohort study using data from Danish nationwide registries, including patients diagnosed with MPN in 2010-2016. Each patient was matched with up to ten comparators without MPN on age, sex, level of education, and region of residence. We assessed pre- and post-diagnosis labor market affiliation, defined as working, unemployed, or receiving sickness benefit, disability pension, retirement pension, or other health-related benefits. Labor market affiliation was assessed weekly from two years pre-diagnosis until death, emigration, or 31 December 2018. For patients and comparators, we reported percentage point (pp) changes in labor market affiliation cross-sectionally from week −104 pre-diagnosis to week 104 post-diagnosis.Results: The study included 3,342 patients with MPN and 32,737 comparators. From two years pre-diagnosis until two years post-diagnosis, a larger reduction in the proportion working was observed among patients than comparators (essential thrombocythemia: 10.2 [95% CI: 6.3–14.1] vs. 6.8 [95% CI: 5.5–8.0] pp; polycythemia vera: 9.6 [95% CI: 5.9–13.2] vs. 7.4 [95% CI: 6.2–8.7] pp; myelofibrosis: 8.1 [95% CI: 3.0–13.2] vs. 5.8 [95% CI: 4.2–7.5] pp; and unclassifiable MPN: 8.0 [95% CI: 3.0–13.0] vs. 7.4 [95% CI: 5.7–9.1] pp). Correspondingly, an increase in the proportion of patients receiving sickness benefits including other health-related benefits was evident around the time of diagnosis.Conclusion: Overall, we found that Danish patients with essential thrombocythemia, polycythemia vera, myelofibrosis, and unclassifiable MPN had slightly impaired labor market affiliation compared with a population of the same age and sex. From two years pre-diagnosis to two years post-diagnosis, we observed a larger reduction in the proportion of patients with MPN working and a greater proportion receiving sickness benefits compared with matched individuals.
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Friis Christensen, SarahDepartment of Hematology, Zealand University Hospital, Denmark
(författare)
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Kjærsgaard, AndersDepartment of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University Hospital and Aarhus University, Denmark
(författare)
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Stenling, AnnaNovartis Sverige AB, Sweden(Swepub:umu)anabei01
(författare)
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Paulsson, BjörnNovartis Sverige AB, Sweden
(författare)
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Andersen, Christen LykkegaardDepartment of Hematology, Copenhagen University Hospital, Rigshospitalet, Denmark
(författare)
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Christiansen, Christian FynboDepartment of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University Hospital and Aarhus University, Denmark
(författare)
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Stentoft, JesperDepartment of Hematology, Aarhus University Hospital, Denmark
(författare)
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Starklint, JørnDepartment of Medicine, Goedstrup Hospital, Denmark
(författare)
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Severinsen, Marianne TangDepartment of Hematology, Aalborg University Hospital, Denmark
(författare)
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Borg Clausen, MetteDepartment of Hematology, Copenhagen University Hospital, Rigshospitalet, Denmark
(författare)
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Hagemann Hilsøe, MortenDepartment of Hematology, Hospital of South West Jutland, Denmark
(författare)
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Hasselbalch, Hans CarlDepartment of Hematology, Zealand University Hospital, Denmark
(författare)
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Frederiksen, HenrikDepartment of Hematology, Odense University Hospital, Denmark
(författare)
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Bak, MarieDepartment of Hematology, Zealand University Hospital, Denmark
(författare)
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Mikkelsen, Ellen MargretheDepartment of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University Hospital and Aarhus University, Denmark
(författare)
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Department of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University Hospital and Aarhus University, DenmarkDepartment of Hematology, Zealand University Hospital, Denmark
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Acta Oncologica: Taylor & Francis0284-186X1651-226X
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