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Sökning: id:"swepub:oai:DiVA.org:umu-215790" > Primary versus earl...

  • Sewalt, Charlie AlettaDepartment of Public Health, Erasmus MC Medical Center, Rotterdam, The Netherlands (författare)

Primary versus early secondary referral to a specialized neurotrauma center in patients with moderate/severe traumatic brain injury : a CENTER TBI study

  • Artikel/kapitelEngelska2021

Förlag, utgivningsår, omfång ...

  • 2021-08-04
  • BioMed Central (BMC),2021
  • electronicrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:umu-215790
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-215790URI
  • https://doi.org/10.1186/s13049-021-00930-1DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-93579URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:147312901URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

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Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • BACKGROUND: Prehospital care for patients with traumatic brain injury (TBI) varies with some emergency medical systems recommending direct transport of patients with moderate to severe TBI to hospitals with specialist neurotrauma care (SNCs). The aim of this study is to assess variation in levels of early secondary referral within European SNCs and to compare the outcomes of directly admitted and secondarily transferred patients.METHODS: Patients with moderate and severe TBI (Glasgow Coma Scale < 13) from the prospective European CENTER-TBI study were included in this study. All participating hospitals were specialist neuroscience centers. First, adjusted between-country differences were analysed using random effects logistic regression where early secondary referral was the dependent variable, and a random intercept for country was included. Second, the adjusted effect of early secondary referral on survival to hospital discharge and functional outcome [6 months Glasgow Outcome Scale Extended (GOSE)] was estimated using logistic and ordinal mixed effects models, respectively.RESULTS: A total of 1347 moderate/severe TBI patients from 53 SNCs in 18 European countries were included. Of these 1347 patients, 195 (14.5%) were admitted after early secondary referral. Secondarily referred moderate/severe TBI patients presented more often with a CT abnormality: mass lesion (52% vs. 34%), midline shift (54% vs. 36%) and acute subdural hematoma (77% vs. 65%). After adjusting for case-mix, there was a large European variation in early secondary referral, with a median OR of 1.69 between countries. Early secondary referral was not associated with functional outcome (adjusted OR 1.07, 95% CI 0.78-1.69), nor with survival at discharge (1.05, 0.58-1.90).CONCLUSIONS: Across Europe, substantial practice variation exists in the proportion of secondarily referred TBI patients at SNCs that is not explained by case mix. Within SNCs early secondary referral does not seem to impact functional outcome and survival after stabilisation in a non-specialised hospital. Future research should identify which patients with TBI truly benefit from direct transportation.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Gravesteijn, Benjamin YaëlDepartment of Public Health, Erasmus MC Medical Center, Rotterdam, The Netherlands; Department of Anesthesiology, Erasmus MC Medical Center, Rotterdam, The Netherlands (författare)
  • Menon, DavidDivision of Anaesthesia, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK (författare)
  • Lingsma, Hester FloorDepartment of Public Health, Erasmus MC Medical Center, Rotterdam, The Netherlands (författare)
  • Maas, Andrew I. R.Department of Neurosurgery, Antwerp University Hospital, and University of Antwerp, Edegem, Belgium (författare)
  • Stocchetti, NinoDepartment of Pathophysiology and Transplantation, Milan University, and Neuroscience ICU, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy (författare)
  • Venema, EsmeeDepartment of Public Health, Erasmus MC Medical Center, Rotterdam, The Netherlands; Department of Neurology, Erasmus MC Medical Center, Rotterdam, The Netherlands (författare)
  • Lecky, Fiona E.Center for Urgent and Emergency Care Research (CURE), Health Services Research Section, School of Health and Related Research (ScHARR), University of Sheffield, Sheffield, UK (författare)
  • Brorsson, CamillaUmeå universitet,Anestesiologi och intensivvård(Swepub:umu)brca0001 (bidragsgivare)
  • Koskinen, Lars-Owe D.,Professor,1955-Umeå universitet,Institutionen för klinisk vetenskap(Swepub:umu)lako0002 (bidragsgivare)
  • Sundström, NinaUmeå universitet,Institutionen för strålningsvetenskaper(Swepub:umu)nian0004 (bidragsgivare)
  • Oresic, Matej,1967-Örebro universitet,Institutionen för medicinska vetenskaper,CENTER TBI Participants and Investigators(Swepub:oru)moc (bidragsgivare)
  • Department of Public Health, Erasmus MC Medical Center, Rotterdam, The NetherlandsDepartment of Public Health, Erasmus MC Medical Center, Rotterdam, The Netherlands; Department of Anesthesiology, Erasmus MC Medical Center, Rotterdam, The Netherlands (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine: BioMed Central (BMC)29:11757-7241

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