Search: WFRF:(Brandmaier Andreas M) >
No phenotypic or ge...
No phenotypic or genotypic evidence for a link between sleep duration and brain atrophy
-
- Fjell, Anders M. (author)
- Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway; Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway
-
- Sørensen, Øystein (author)
- Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway
-
- Wang, Yunpeng (author)
- Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway
-
show more...
-
- Amlien, Inge K. (author)
- Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway
-
- Baaré, William F. C. (author)
- Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital—Amager and Hvidovre, Copenhagen, Denmark
-
- Bartrés-Faz, David (author)
- Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona, Barcelona, Spain; Institut de Neurociències, Universitat de Barcelona, Barcelona, Spain; Institut d’Investigacions Biomèdiques August Pii Sunyer, Barcelona, Spain
-
- Bertram, Lars (author)
- Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway; Lübeck Interdisciplinary Platform for Genome Analytics, University of Lübeck, Lübeck, Germany
-
- Boraxbekk, Carl-Johan, 1980- (author)
- Umeå universitet,Umeå centrum för funktionell hjärnavbildning (UFBI),Diagnostisk radiologi,Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital—Amager and Hvidovre, Copenhagen, Denmark; Institute of Sports Medicine Copenhagen, Copenhagen University Hospital Bispebjerg, Copenhagen, Denmark
-
- Brandmaier, Andreas M. (author)
- Center for Lifespan Psychology, Max Planck Institute for Human Development, Berlin, Germany; Department of Psychology, MSB Medical School Berlin, Berlin, Germany
-
- Demuth, Ilja (author)
- Department of Endocrinology and Metabolic Diseases (including Division of Lipid Metabolism), Biology of Aging Working Group, Charité—Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany; Berlin Institute of Health Center for Regenerative Therapies, Berlin Institute of Health at Charité—Universitätsmedizin Berlin, Berlin, Germany
-
- Drevon, Christian A. (author)
- Vitas AS, Oslo, Norway; Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway
-
- Ebmeier, Klaus P. (author)
- Department of Psychiatry, University of Oxford, Oxford, United Kingdom
-
- Ghisletta, Paolo (author)
- Faculty of Psychology and Educational Sciences, University of Geneva, Geneva, Switzerland; UniDistance Suisse, Brig, Switzerland; Swiss National Centre of Competence in Research LIVES, University of Geneva, Geneva, Switzerland
-
- Kievit, Rogier (author)
- Cognitive Neuroscience Department, Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, Netherlands
-
- Kühn, Simone (author)
- Center for Lifespan Psychology, Max Planck Institute for Human Development, Berlin, Germany; Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
-
- Madsen, Kathrine Skak (author)
- Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital—Amager and Hvidovre, Copenhagen, Denmark; Radiography, Department of Technology, University College Copenhagen, Copenhagen, Denmark
-
- Mowinckel, Athanasia M. (author)
- Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway
-
- Nyberg, Lars, 1966- (author)
- Umeå universitet,Umeå centrum för funktionell hjärnavbildning (UFBI),Institutionen för strålningsvetenskaper,Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway
-
- Sexton, Claire E. (author)
- Department of Psychiatry, University of Oxford, Oxford, United Kingdom; Global Brain Health Institute, Department of Neurology, University of California, San Francisco, CA, San Francisco, United States; Wellcome Centre for Integrative Neuroimaging, University of Oxford, Oxford, United Kingdom; Alzheimer’s Association, IL, Chicago, United States
-
- Solé-Padullés, Cristina (author)
- Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona, Barcelona, Spain; Institut de Neurociències, Universitat de Barcelona, Barcelona, Spain; Institut d’Investigacions Biomèdiques August Pii Sunyer, Barcelona, Spain
-
- Vidal-Piñeiro, Didac (author)
- Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway
-
- Wagner, Gerd (author)
- Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany
-
- Watne, Leiv Otto (author)
- Oslo Delirium Research Group, Department of Geriatric Medicine, University of Oslo, Oslo, Norway; Department of Geriatric Medicine, Akershus University Hospital, Lørenskog, Norway
-
- Walhovd, Kristine B. (author)
- Center for Lifespan Changes in Brain and Cognition, University of Oslo, Oslo, Norway; Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway
-
show less...
-
(creator_code:org_t)
- Springer Nature, 2023
- 2023
- English.
-
In: Nature Human Behaviour. - : Springer Nature. - 2397-3374. ; 7:11, s. 2008-2022
- Related links:
-
https://doi.org/10.1...
-
show more...
-
https://umu.diva-por... (primary) (Raw object)
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- Short sleep is held to cause poorer brain health, but is short sleep associated with higher rates of brain structural decline? Analysing 8,153 longitudinal MRIs from 3,893 healthy adults, we found no evidence for an association between sleep duration and brain atrophy. In contrast, cross-sectional analyses (51,295 observations) showed inverse U-shaped relationships, where a duration of 6.5 (95% confidence interval, (5.7, 7.3)) hours was associated with the thickest cortex and largest volumes relative to intracranial volume. This fits converging evidence from research on mortality, health and cognition that points to roughly seven hours being associated with good health. Genome-wide association analyses suggested that genes associated with longer sleep for below-average sleepers were linked to shorter sleep for above-average sleepers. Mendelian randomization did not yield evidence for causal impacts of sleep on brain structure. The combined results challenge the notion that habitual short sleep causes brain atrophy, suggesting that normal brains promote adequate sleep duration—which is shorter than current recommendations.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
-
Fjell, Anders M.
-
Sørensen, Øystei ...
-
Wang, Yunpeng
-
Amlien, Inge K.
-
Baaré, William F ...
-
Bartrés-Faz, Dav ...
-
show more...
-
Bertram, Lars
-
Boraxbekk, Carl- ...
-
Brandmaier, Andr ...
-
Demuth, Ilja
-
Drevon, Christia ...
-
Ebmeier, Klaus P ...
-
Ghisletta, Paolo
-
Kievit, Rogier
-
Kühn, Simone
-
Madsen, Kathrine ...
-
Mowinckel, Athan ...
-
Nyberg, Lars, 19 ...
-
Sexton, Claire E ...
-
Solé-Padullés, C ...
-
Vidal-Piñeiro, D ...
-
Wagner, Gerd
-
Watne, Leiv Otto
-
Walhovd, Kristin ...
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Basic Medicine
-
and Neurosciences
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Neurology
- Articles in the publication
-
Nature Human Beh ...
- By the university
-
Umeå University