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Sökning: WFRF:(Rogiers S) > (2020-2024) > Understanding quali...

Understanding quality of life issues in patients with advanced melanoma : Phase 1 and 2 in the development of the EORTC advanced melanoma module

Egeler, M.D. (författare)
Netherlands Cancer Institute, Amsterdam, Netherlands
van Leeuwen, M. (författare)
Netherlands Cancer Institute, Amsterdam, Netherlands
Lai-Kwon, J. (författare)
Department of Medical Oncology and Department of Health Services Research, Peter MacCallum Cancer Centre, Melbourne, Australia
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Eriksson, H. (författare)
Theme Cancer, Karolinska University Hospital, Stockholm, Sweden; Department of Oncology-Pathology, Karolinska Institutet, Sweden
Bartula, I. (författare)
Melanoma Institute Australia, The University of Sydney, Sydney, Australia
Elashwah, S. (författare)
Medical Oncology Unit, Oncology Center, Mansoura University (OCMU), Egypt
Fox, L. (författare)
King's College London, London, United Kingdom
Van Hemelrijck, M. (författare)
King's College London, London, United Kingdom
Jefford, M. (författare)
Department of Medical Oncology and Department of Health Services Research, Peter MacCallum Cancer Centre, Melbourne, Australia
Lijnsvelt, J. (författare)
Netherlands Cancer Institute, Department of Medical Oncology, Amsterdam, Netherlands
Bagge, A.-S. Lindqvist (författare)
Sahlgrenska Center for Cancer Research, Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Psychology, University of Gothenburg, Gothenburg, Sweden
Morag, O. (författare)
Sheba Medical Center, The Jusjdman Cancer Center, Ramat-gan, Israel
Ny, L. (författare)
Sahlgrenska Center for Cancer Research, Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Bagge, R. Olofsson (författare)
Sahlgrenska Center for Cancer Research, Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Rogiers, A. (författare)
Department of Medical Oncology, Vrije Universiteit Brussel, Universitair Ziekenhuis Brussel, Brussels, Belgium
Saw, R.P.M. (författare)
Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, NSW, Sydney, Australia; Department of Melanoma and Surgical Oncology, Royal Prince Alfred Hospital, NSW, Sydney, Australia
Serpentini, S. (författare)
Veneto Institute of Oncology, Veneto, Italy
Iannopollo, L. (författare)
Veneto Institute of Oncology, Veneto, Italy
Thompson, J. (författare)
Melanoma Institute Australia, The University of Sydney, Sydney, Australia
Tufvesson Stiller, Helena (författare)
Umeå universitet,Institutionen för folkhälsa och klinisk medicin
Vanlaer, N. (författare)
Sheba Medical Center, The Jusjdman Cancer Center, Ramat-gan, Israel
van Akkooi, A.C.J. (författare)
Melanoma Institute Australia, The University of Sydney, Sydney, Australia; Faculty of Medicine and Health, The University of Sydney, NSW, Sydney, Australia; Department of Melanoma and Surgical Oncology, Royal Prince Alfred Hospital, NSW, Sydney, Australia
van de Poll-Franse, L.V. (författare)
Netherlands Cancer Institute, Amsterdam, Netherlands
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 (creator_code:org_t)
Elsevier, 2024
2024
Engelska.
Ingår i: European Journal of Cancer. - : Elsevier. - 0959-8049 .- 1879-0852. ; 207
Relaterad länk:
https://urn.kb.se/re...
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https://doi.org/10.1...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Aims: We aimed to develop a European Organization for Research and Treatment of Cancer (EORTC) Quality of Life (QoL) module tailored for patients with advanced (resectable or unresectable stage III/IV) melanoma receiving immune checkpoint inhibitors or targeted therapy.Methods: Following the EORTC QoL Group module development guidelines, we conducted phases 1 and 2 of the development process. In phase 1, we generated a list of health-related (HR)QoL issues through a systematic literature review and semi-structured interviews with healthcare professionals (HCPs) and patients with advanced melanoma. In phase 2, these issues were converted into questionnaire items to create the preliminary module.Results: Phase 1: we retrieved 8006 articles for the literature review, of which 35 were deemed relevant, resulting in 84 HRQoL issues being extracted to create the initial issue list. Semi-structured interviews with 18 HCPs and 28 patients with advanced melanoma resulted in 28 issues being added to the initial issue list. Following EORTC module development criteria, 26 issues were removed, and two issues were added after review by patient advocates.Phase 2: To ensure uniformity and avoid duplication, 16 issues were consolidated into eight items. Additionally, an independent expert contributed one new item, resulting in a preliminary module comprising 80 HRQoL items.Conclusion: We identified a range of HRQoL issues (dry skin, xerostomia, and arthralgia) relevant to patients with stage III/IV melanoma. Future module development phases will refine the questionnaire. Once completed, this module will enable standardized assessment of HRQoL in patients with (locally) advanced melanoma.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)

Nyckelord

Melanoma
Quality of life

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