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  • Hebib, LanaDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden (författare)

Life’s Essential 8 is inversely associated with high-sensitivity C-reactive protein

  • Artikel/kapitelEngelska2024

Förlag, utgivningsår, omfång ...

  • Springer Nature,2024
  • electronicrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:umu-227840
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-227840URI
  • https://doi.org/10.1038/s41598-024-65977-3DOI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

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Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Life’s Essential 8 (LE8) is a score that includes modifiable risk factors for cardiovascular disease. Four health behaviors (diet, physical activity, nicotine exposure and sleep health) and four health factors (non-HDL cholesterol, blood glucose, blood pressure and body mass index) are included. These modifiable risk factors promote inflammation, and inflammation is one of the biological mechanisms of cardiovascular disease development. Thus, we examined the relationship between cardiovascular health measured by LE8 and low-grade inflammation measured by high-sensitivity C-reactive protein (hs-CRP) in the cross-sectional population-based Swedish CArdioPulmonary bioImage Study (SCAPIS). The study consisted of 28,010 participants between 50 and 64 years (51.5% women, mean age 57.5 years). All individual LE8 components were assigned a score between 0 (unhealthy) and 100 (healthy) points, and a global score was calculated. The association between LE8 scores and high-risk hs-CRP (defined as > 3.0 mg/L) was analyzed using adjusted logistic regression with spline analyses. There was a strong, dose response and inverse association between LE8 scores and levels of hs-CRP. Thus, those with a low LE8 score (= 50.0 points) had 5.8 higher (95% confidence interval [CI] 5.2–6.4) odds ratio (OR) of having high hs-CRP as compared to those with a high LE8 score (= 80.0 points). In conclusion, our findings show strong inverse associations between LE8 scores and levels of hs-CRP.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Herraiz-Adillo, ÁngelDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden (författare)
  • Higueras-Fresnillo, SaraDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden; Department Physical Education, Sport and Human Motricity, Universidad Autónoma de Madrid, Madrid, Spain (författare)
  • Berglind, DanielDepartment of Global Public Health, Karolinska Institutet, Stockholm, Sweden; Centre for Epidemiology and Community Medicine, Region Stockholm, Stockholm, Sweden (författare)
  • Daka, BledarSchool of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden (författare)
  • Wennberg, Patrik,1972-Umeå universitet,Institutionen för folkhälsa och klinisk medicin(Swepub:umu)pawe0002 (författare)
  • Hagström, EmilDepartment of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden (författare)
  • Lenander, CeciliaDepartment of Clinical Sciences in Malmö, Centre for Primary Health Care Research, Lund University, Lund, Sweden (författare)
  • Ahlqvist, Viktor H.Department of Biomedicine, Aarhus University, Aarhus, Denmark; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden (författare)
  • Östgren, Carl JohanDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden; Centre for Medical Image Science and Visualization (CMIV), Linköping University, Linköping, Sweden (författare)
  • Rådholm, KarinDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden; The George Institute for Global Health, University of New South Wales, Sydney, Australia (författare)
  • Henriksson, PontusDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden (författare)
  • Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, SwedenDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden; Department Physical Education, Sport and Human Motricity, Universidad Autónoma de Madrid, Madrid, Spain (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Scientific Reports: Springer Nature14:12045-2322

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