WFRF:(Ambarki Khalid)
Sökning: WFRF:(Ambarki Khalid) > Transcranial Dopple...
- Behrens, AndersUmeå universitet,Neurologi (författare)
Transcranial Doppler pulsatility index: not an accurate method to assess intracranial pressure.
- Artikel/kapitelEngelska2010
Förlag, utgivningsår, omfång ...
- 2010
- printrdacarrier
Nummerbeteckningar
- LIBRIS-ID:oai:DiVA.org:umu-34863
- https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-34863URI
- https://doi.org/10.1227/01.NEU.0000369519.35932.F2DOI
Kompletterande språkuppgifter
- Språk:engelska
- Sammanfattning på:engelska
Ingår i deldatabas
- SwePubSwePub
Klassifikation
Anmärkningar
- BACKGROUND: Transcranial Doppler sonography (TCD) assessment of intracranial blood flow velocity has been suggested to accurately determine intracranial pressure (ICP). OBJECTIVE: We attempted to validate this method in patients with communicating cerebrospinal fluid systems using predetermined pressure levels. METHODS: Ten patients underwent a lumbar infusion test, applying 4 to 5 preset ICP levels. On each level, the pulsatility index (PI) in the middle cerebral artery was determined by measuring the blood flow velocity using TCD. ICP was simultaneously measured with an intraparenchymal sensor. ICP and PI were compared using correlation analysis. For further understanding of the ICP-PI relationship, a mathematical model of the intracranial dynamics was simulated using a computer. RESULTS: The ICP-PI regression equation was based on data from 8 patients. For 2 patients, no audible Doppler signal was obtained. The equation was ICP = 23*PI + 14 (R = 0.22, P < .01, N = 35). The 95% confidence interval for a mean ICP of 20 mm Hg was -3.8 to 43.8 mm Hg. Individually, the regression coefficients varied from 42 to 90 and the offsets from -32 to +3. The mathematical simulations suggest that variations in vessel compliance, autoregulation, and arterial pressure have a serious effect on the ICP-PI relationship. CONCLUSIONS: The in vivo results show that PI is not a reliable predictor of ICP. Mathematical simulations indicate that this is caused by variations in physiological parameters.
Ämnesord och genrebeteckningar
- Blood flow velocity
- hydrocephalus
- intracranial pressure
- middle cerebral artery
- pulsatility indix
- MEDICINE
- MEDICIN
Biuppslag (personer, institutioner, konferenser, titlar ...)
- Lenfeldt, NiklasUmeå universitet,Neurologi(Swepub:umu)nislet97 (författare)
- Ambarki, KhalidUmeå universitet,Radiofysik(Swepub:umu)kham0001 (författare)
- Malm, JanUmeå universitet,Neurologi(Swepub:umu)jama0002 (författare)
- Eklund, AndersUmeå universitet,Radiofysik(Swepub:umu)anek0025 (författare)
- Koskinen, Lars-OweUmeå universitet,Neurokirurgi(Swepub:umu)lako0002 (författare)
- Umeå universitetNeurologi (creator_code:org_t)
Sammanhörande titlar
- Ingår i:Neurosurgery66:6, s. 1050-10570148-396X1524-4040
Internetlänk
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- Av författaren/redakt...
- Behrens, Anders
- Lenfeldt, Niklas
- Ambarki, Khalid
- Malm, Jan
- Eklund, Anders
- Koskinen, Lars-O ...
- Artiklar i publikationen
- Neurosurgery
- Av lärosätet
- Umeå universitet
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