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Testicular enlargem...
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Dahlqvist, PerUmeå universitet,Medicin
(författare)
Testicular enlargement in a patient with a FSH-secreting pituitary adenoma
- Artikel/kapitelEngelska2010
Förlag, utgivningsår, omfång ...
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2010-01-20
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Springer Science and Business Media LLC,2010
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:umu-38722
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-38722URI
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https://doi.org/10.1007/s12020-009-9302-zDOI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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Clinically non-functional pituitary adenomas are often derived from gonadotropin producing cells. However, gonadotropinomas causing elevated serum levels of follicle-stimulating hormone (FSH) and clinical signs of FSH hypersecretion are very rarely described. Our patient, a 56-year-old man, was referred to our clinic with signs of hypogonadism. Magnetic resonance imaging (MRI) and biochemical examinations showed a large pituitary adenoma and excessive levels of serum FSH. Clinical examination and ultrasound measurement revealed bilaterally enlarged testes. After pituitary surgery, serum FSH levels normalized and there was a decrease in testicular volume. This case suggests that supraphysiological levels of FSH from a gonadotropinoma can cause a clinically observable effect, i.e. testicular enlargement. This is in line with experimental studies showing biological effect of FSH from pituitary adenomas and previous occasional reports of ovarian hyperstimulation and testicular enlargement in patients with FSH-secreting gonadotropinomas.
Ämnesord och genrebeteckningar
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Pituitary adenoma
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Follicle-stimulating hormone
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Testis
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MEDICINE
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MEDICIN
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patologi
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Pathology
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Koskinen, Lars-Owe DUmeå universitet,Neurokirurgi(Swepub:umu)lako0002
(författare)
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Brännström, ThomasUmeå universitet,Patologi(Swepub:umu)thbr0001
(författare)
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Hägg, ErikUmeå universitet,Medicin
(författare)
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Umeå universitetMedicin
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Endocrine: Springer Science and Business Media LLC37:2, s. 289-2931355-008X1559-0100
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