Search: id:"swepub:oai:DiVA.org:umu-39667" >
Distinct ethnic dif...
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Zhang, LeiDepartment of Public Health, University of Helsinki, FIN-00014 Helsinki, Finland
(author)
Distinct ethnic differences in lipid profiles across glucose categories
- Article/chapterEnglish2010
Publisher, publication year, extent ...
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The Endocrine Society,2010
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LIBRIS-ID:oai:DiVA.org:umu-39667
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-39667URI
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https://doi.org/10.1210/jc.2009-2348DOI
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
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Context: Dyslipidemia coexists with hyperglycemia. However, little is known about the ethnic differences in lipid profiles at comparable glucose tolerance status. Objective: The aim was to study ethnic differences in lipid profiles stratified by glucose levels. Design and Setting: Data from 31 study cohorts of 12 countries, consisting of 24,760 men and 27,595 women aged 25–74 yr, were compared. The odds ratio for having dyslipidemia was estimated for each ethnic group stratified by glucose categories. Results: Compared with central and northern Europeans, multivariable adjusted odds ratios (95% confidence intervals) for having lower high-density lipoprotein-cholesterol were 4.74 (4.19–5.37), 5.05 (3.88–6.56), 3.07 (2.15–4.40), and 2.37 (1.67–3.35) in Asian Indian men, but 0.12 (0.09–0.16), 0.07 (0.04–0.13), 0.11 (0.07–0.20), and 0.16 (0.08–0.32) in Chinese men who had normoglycemia, prediabetes, and undiagnosed and diagnosed diabetes, respectively. Similar results were obtained for women. The prevalence of low high-density lipoprotein-cholesterol remained higher in Asian Indians (62.8% of the nondiabetic and 67.4% of the diabetic) than in central and northern Europeans (20.3 and 37.3%), Japanese (25.7 and 34.1%), or Qingdao Chinese (15.7 and 17.0%), even in individuals with low-density lipoprotein-cholesterol of less than 3 mmol/liter. Conclusion: There are distinct patterns of lipid profiles associated with ethnicity regardless of the glucose levels, suggesting that ethnic-specific strategies and guidelines on risk assessment and prevention of cardiovascular disease are required.
Added entries (persons, corporate bodies, meetings, titles ...)
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Qiao, QingDepartment of Public Health, University of Helsinki, FIN-00014 Helsinki, Finland
(author)
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Tuomilehto, JaakkoDepartment of Public Health, University of Helsinki, FIN-00014 Helsinki, Finland
(author)
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Janus, Edward DDepartment of Medicine, University of Melbourne, Western Hospital, Footscray, VIC 3011, Australia
(author)
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Lam, Tai HingDepartment of Community Medicine, School of Public Health, University of Hong Kong, Hong Kong, China
(author)
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Ramachandran, AmbadyIndia Diabetes Research Foundation and Dr. A. Ramachandran’s Diabetes Hospitals, Egmore, Chennai 600 008, India
(author)
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Mohan, ViswanathanMadras Diabetes Research Foundation and Dr. Mohan’s Diabetes Specialities Centre, Chennai 600 086, India
(author)
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Stehouwer, Coen D ADepartment of Internal Medicine and Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, 6202 AZ Maastricht, The Netherlands
(author)
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Dong, YanhuQingdao Endocrinology and Diabetes Hospital and Institute, 266071 Qingdao, China
(author)
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Nakagami, TomokoDiabetes Center, Tokyo Women’s Medical University School of Medicine, 162-8666 Tokyo, Japan
(author)
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Onat, AltanTurkish Society of Cardiology, Istanbul University, Istanbul 34452, Turkey
(author)
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Söderberg, StefanUmeå universitet,Medicin(Swepub:umu)stso0001
(author)
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Department of Public Health, University of Helsinki, FIN-00014 Helsinki, FinlandDepartment of Medicine, University of Melbourne, Western Hospital, Footscray, VIC 3011, Australia
(creator_code:org_t)
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In:Journal of Clinical Endocrinology and Metabolism: The Endocrine Society95:4, s. 1793-18010021-972X1945-7197
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