Evaluation of rapid diagnostic tests for malaria in Swedish travellers

Rapid diagnostic tests (RDTs) for malaria have become valuable tools for the diagnosis of malaria in both endemic and non-endemic areas. During a 7-year period, first the MalaQuick rapid test and then the NOW Malaria test, were evaluated by well-trained laboratory technicians in a university hospital laboratory of parasitology. A total of 635 blood samples were selected from 4731 blood specimens obtained from travellers at the emergency department, at wards and at out-patient clinics. The samples were analysed by microscopy and RDT. Malaria parasites were detected in the blood films of 134 (21%) samples. The sensitivity of the RDT for Plasmodium falciparum was 97.7% (84 of 86 samples) with a negative predictive value of 99.6%. The two false-negative results were associated with low levels of parasitaemia. For non-falciparum species the sensitivity was only 58.3% (28 of 48 samples). Based on the excellent ability of the RDTs to detect P. falciparum infections, we recommend the use of the NOW Malaria test as a complement to microscopy in the laboratory.

Karlsson, Lillemor (författare)
Evengård, Birgitta,1952-Umeå universitet,Infektionssjukdomar(Swepub:umu)biev0002 (författare)
Umeå universitetInfektionssjukdomar (creator_code:org_t)

Ingår i:Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS): Wiley119:2, s. 88-920903-46411600-0463

Av författaren/redakt...: Bronner, Ulf; Karlsson, Lillem ...; Evengård, Birgit ...

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Infektionsmedici ...

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