Search: (WFRF:(Davis Adrian)) srt2:(2010-2014) >
Identification of f...
Identification of functional elements and regulatory circuits by Drosophila modENCODE.
- Article/chapterEnglish2010
Publisher, publication year, extent ...
-
American Association for the Advancement of Science (AAAS),2010
-
printrdacarrier
Numbers
-
LIBRIS-ID:oai:DiVA.org:umu-46221
-
https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-46221URI
-
https://doi.org/10.1126/science.1198374DOI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:ref swepub-contenttype
-
Subject category:art swepub-publicationtype
Notes
-
To gain insight into how genomic information is translated into cellular and developmental programs, the Drosophila model organism Encyclopedia of DNA Elements (modENCODE) project is comprehensively mapping transcripts, histone modifications, chromosomal proteins, transcription factors, replication proteins and intermediates, and nucleosome properties across a developmental time course and in multiple cell lines. We have generated more than 700 data sets and discovered protein-coding, noncoding, RNA regulatory, replication, and chromatin elements, more than tripling the annotated portion of the Drosophila genome. Correlated activity patterns of these elements reveal a functional regulatory network, which predicts putative new functions for genes, reveals stage- and tissue-specific regulators, and enables gene-expression prediction. Our results provide a foundation for directed experimental and computational studies in Drosophila and related species and also a model for systematic data integration toward comprehensive genomic and functional annotation.
Added entries (persons, corporate bodies, meetings, titles ...)
-
Ernst, Jason
(author)
-
Kharchenko, Peter V
(author)
-
Kheradpour, Pouya
(author)
-
Negre, Nicolas
(author)
-
Eaton, Matthew L
(author)
-
Landolin, Jane M
(author)
-
Bristow, Christopher A
(author)
-
Ma, Lijia
(author)
-
Lin, Michael F
(author)
-
Washietl, Stefan
(author)
-
Arshinoff, Bradley I
(author)
-
Ay, Ferhat
(author)
-
Meyer, Patrick E
(author)
-
Robine, Nicolas
(author)
-
Washington, Nicole L
(author)
-
Di Stefano, Luisa
(author)
-
Berezikov, Eugene
(author)
-
Brown, Christopher D
(author)
-
Candeias, Rogerio
(author)
-
Carlson, Joseph W
(author)
-
Carr, Adrian
(author)
-
Jungreis, Irwin
(author)
-
Marbach, Daniel
(author)
-
Sealfon, Rachel
(author)
-
Tolstorukov, Michael Y
(author)
-
Will, Sebastian
(author)
-
Alekseyenko, Artyom A
(author)
-
Artieri, Carlo
(author)
-
Booth, Benjamin W
(author)
-
Brooks, Angela N
(author)
-
Dai, Qi
(author)
-
Davis, Carrie A
(author)
-
Duff, Michael O
(author)
-
Feng, Xin
(author)
-
Gorchakov, Andrey A
(author)
-
Gu, Tingting
(author)
-
Henikoff, Jorja G
(author)
-
Kapranov, Philipp
(author)
-
Li, Renhua
(author)
-
MacAlpine, Heather K
(author)
-
Malone, John
(author)
-
Minoda, Aki
(author)
-
Nordman, Jared
(author)
-
Okamura, Katsutomo
(author)
-
Perry, Marc
(author)
-
Powell, Sara K
(author)
-
Riddle, Nicole C
(author)
-
Sakai, Akiko
(author)
-
Samsonova, Anastasia
(author)
-
Sandler, Jeremy E
(author)
-
Schwartz, Yuri BRutgers University, New Jersey, USA(Swepub:umu)yusc0002
(author)
-
Sher, Noa
(author)
-
Spokony, Rebecca
(author)
-
Sturgill, David
(author)
-
van Baren, Marijke
(author)
-
Wan, Kenneth H
(author)
-
Yang, Li
(author)
-
Yu, Charles
(author)
-
Feingold, Elise
(author)
-
Good, Peter
(author)
-
Guyer, Mark
(author)
-
Lowdon, Rebecca
(author)
-
Ahmad, Kami
(author)
-
Andrews, Justen
(author)
-
Berger, Bonnie
(author)
-
Brenner, Steven E
(author)
-
Brent, Michael R
(author)
-
Cherbas, Lucy
(author)
-
Elgin, Sarah C R
(author)
-
Gingeras, Thomas R
(author)
-
Grossman, Robert
(author)
-
Hoskins, Roger A
(author)
-
Kaufman, Thomas C
(author)
-
Kent, William
(author)
-
Kuroda, Mitzi I
(author)
-
Orr-Weaver, Terry
(author)
-
Perrimon, Norbert
(author)
-
Pirrotta, Vincenzo
(author)
-
Posakony, James W
(author)
-
Ren, Bing
(author)
-
Russell, Steven
(author)
-
Cherbas, Peter
(author)
-
Graveley, Brenton R
(author)
-
Lewis, Suzanna
(author)
-
Micklem, Gos
(author)
-
Oliver, Brian
(author)
-
Park, Peter J
(author)
-
Celniker, Susan E
(author)
-
Henikoff, Steven
(author)
-
Karpen, Gary H
(author)
-
Lai, Eric C
(author)
-
MacAlpine, David M
(author)
-
Stein, Lincoln D
(author)
-
White, Kevin P
(author)
-
Kellis, Manolis
(author)
-
Rutgers University, New Jersey, USA
(creator_code:org_t)
Related titles
-
In:Science (New York, N.Y.): American Association for the Advancement of Science (AAAS)330:6012, s. 1787-17971095-92030036-8075
Internet link
Find in a library
To the university's database
- By the author/editor
-
Roy, Sushmita
-
Ernst, Jason
-
Kharchenko, Pete ...
-
Kheradpour, Pouy ...
-
Negre, Nicolas
-
Eaton, Matthew L
-
show more...
-
Landolin, Jane M
-
Bristow, Christo ...
-
Ma, Lijia
-
Lin, Michael F
-
Washietl, Stefan
-
Arshinoff, Bradl ...
-
Ay, Ferhat
-
Meyer, Patrick E
-
Robine, Nicolas
-
Washington, Nico ...
-
Di Stefano, Luis ...
-
Berezikov, Eugen ...
-
Brown, Christoph ...
-
Candeias, Rogeri ...
-
Carlson, Joseph ...
-
Carr, Adrian
-
Jungreis, Irwin
-
Marbach, Daniel
-
Sealfon, Rachel
-
Tolstorukov, Mic ...
-
Will, Sebastian
-
Alekseyenko, Art ...
-
Artieri, Carlo
-
Booth, Benjamin ...
-
Brooks, Angela N
-
Dai, Qi
-
Davis, Carrie A
-
Duff, Michael O
-
Feng, Xin
-
Gorchakov, Andre ...
-
Gu, Tingting
-
Henikoff, Jorja ...
-
Kapranov, Philip ...
-
Li, Renhua
-
MacAlpine, Heath ...
-
Malone, John
-
Minoda, Aki
-
Nordman, Jared
-
Okamura, Katsuto ...
-
Perry, Marc
-
Powell, Sara K
-
Riddle, Nicole C
-
Sakai, Akiko
-
Samsonova, Anast ...
-
Sandler, Jeremy ...
-
Schwartz, Yuri B
-
Sher, Noa
-
Spokony, Rebecca
-
Sturgill, David
-
van Baren, Marij ...
-
Wan, Kenneth H
-
Yang, Li
-
Yu, Charles
-
Feingold, Elise
-
Good, Peter
-
Guyer, Mark
-
Lowdon, Rebecca
-
Ahmad, Kami
-
Andrews, Justen
-
Berger, Bonnie
-
Brenner, Steven ...
-
Brent, Michael R
-
Cherbas, Lucy
-
Elgin, Sarah C R
-
Gingeras, Thomas ...
-
Grossman, Robert
-
Hoskins, Roger A
-
Kaufman, Thomas ...
-
Kent, William
-
Kuroda, Mitzi I
-
Orr-Weaver, Terr ...
-
Perrimon, Norber ...
-
Pirrotta, Vincen ...
-
Posakony, James ...
-
Ren, Bing
-
Russell, Steven
-
Cherbas, Peter
-
Graveley, Brento ...
-
Lewis, Suzanna
-
Micklem, Gos
-
Oliver, Brian
-
Park, Peter J
-
Celniker, Susan ...
-
Henikoff, Steven
-
Karpen, Gary H
-
Lai, Eric C
-
MacAlpine, David ...
-
Stein, Lincoln D
-
White, Kevin P
-
Kellis, Manolis
-
show less...
- Articles in the publication
-
Science (New Yor ...
- By the university
-
Umeå University