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  • Dobbins, Sara E. (author)

Common variation at 10p12.31 near MLLT10 influences meningioma risk

  • Article/chapterEnglish2011

Publisher, publication year, extent ...

  • 2011-07-31
  • London :Nature America, Inc.2011
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:umu-47382
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-47382URI
  • https://doi.org/10.1038/ng.879DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:123171875URI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • To identify susceptibility loci for meningioma, we conducted a genome-wide association study of 859 affected individuals (cases) and 704 controls with validation in two independent sample sets totaling 774 cases and 1,764 controls. We identified a new susceptibility locus for meningioma at 10p12.31 (MLLT10, rs11012732, odds ratio = 1.46, P(combined) = 1.88 x 10(-14)). This finding advances our understanding of the genetic basis of meningioma development.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Broderick, Peter (author)
  • Melin, BeatriceUmeå universitet,Onkologi(Swepub:umu)bema0010 (author)
  • Feychting, MariaKarolinska Institutet (author)
  • Johansen, Christoffer (author)
  • Andersson, UlrikaUmeå universitet,Onkologi(Swepub:umu)ulan0002 (author)
  • Brännström, ThomasUmeå universitet,Institutionen för medicinsk biovetenskap(Swepub:umu)thbr0001 (author)
  • Schramm, Johannes (author)
  • Olver, Bianca (author)
  • Lloyd, Amy (author)
  • Ma, Yussanne P. (author)
  • Hosking, Fay J. (author)
  • Lönn, StefanKarolinska Institutet (author)
  • Ahlbom, AndersKarolinska Institutet (author)
  • Henriksson, RogerUmeå universitet,Onkologi(Swepub:umu)rohe0003 (author)
  • Schoemaker, Minouk J. (author)
  • Hepworth, Sarah J. (author)
  • Hoffmann, Per (author)
  • Muehleisen, Thomas W. (author)
  • Noethen, Markus M. (author)
  • Moebus, Susanne (author)
  • Eisele, Lewin (author)
  • Kosteljanetz, Michael (author)
  • Muir, Kenneth (author)
  • Swerdlow, Anthony (author)
  • Simon, Matthias (author)
  • Houlston, Richard S. (author)
  • Umeå universitetOnkologi (creator_code:org_t)

Related titles

  • In:Nature GeneticsLondon : Nature America, Inc.43:9, s. 825-8271061-40361546-1718

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