Search: (WFRF:(Teras Lauren R)) pers:(Yeager Meredith) pers:(Giovannucci Edward) >
Detectable clonal m...
Detectable clonal mosaicism and its relationship to aging and cancer.
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- Jacobs, Kevin B (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.;NCI, Core Genotyping Facil, SAIC Frederick Inc, Frederick, MD 21701 USA.
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- Yeager, Meredith (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.;NCI, Core Genotyping Facil, SAIC Frederick Inc, Frederick, MD 21701 USA.
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- Zhou, Weiyin (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.;NCI, Core Genotyping Facil, SAIC Frederick Inc, Frederick, MD 21701 USA.
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- Wacholder, Sholom (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Wang, Zhaoming (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.;NCI, Core Genotyping Facil, SAIC Frederick Inc, Frederick, MD 21701 USA.
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- Rodriguez-Santiago, Benjamin (author)
- Univ Pompeu Fabra, Dept Ciencies Expt & Salut, Barcelona, Spain.;Ctr Invest Biomed Red Enfermedades Raras CIBERER, Barcelona, Spain.;qGenomics, Quantitat Genom Med Lab, Barcelona, Spain.
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- Hutchinson, Amy (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.;NCI, Core Genotyping Facil, SAIC Frederick Inc, Frederick, MD 21701 USA.
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- Deng, Xiang (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.;NCI, Core Genotyping Facil, SAIC Frederick Inc, Frederick, MD 21701 USA.
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- Liu, Chenwei (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.;NCI, Core Genotyping Facil, SAIC Frederick Inc, Frederick, MD 21701 USA.
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- Horner, Marie-Josephe (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Cullen, Michael (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.;NCI, Core Genotyping Facil, SAIC Frederick Inc, Frederick, MD 21701 USA.,NCI, Expt Immunol Lab, Ctr Canc Res, Frederick, MD 21701 USA.
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- Epstein, Caroline G (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Burdett, Laurie (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.;NCI, Core Genotyping Facil, SAIC Frederick Inc, Frederick, MD 21701 USA.
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Dean, Michael C (author)
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- Chatterjee, Nilanjan (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Sampson, Joshua (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Chung, Charles C (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.,Vanderbilt Univ, Sch Med, Dept Thorac Surg, Nashville, TN 37212 USA.;Vanderbilt Univ, Med Ctr, Dept Med, Div Epidemiol,Vanderbilt Epidemiol Ctr, Nashville, TN USA.,NCI, Human Carcinogenesis Lab, Ctr Canc Res, Bethesda, MD 20892 USA.,Mem Sloan Kettering Canc Ctr, Dept Med, New York, NY 10021 USA.
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- Kovaks, Joseph (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Gapstur, Susan M (author)
- Amer Canc Soc, Epidemiol Res Program, Atlanta, GA 30329 USA.
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- Stevens, Victoria L (author)
- Amer Canc Soc, Epidemiol Res Program, Atlanta, GA 30329 USA.,NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Teras, Lauren T (author)
- Amer Canc Soc, Epidemiol Res Program, Atlanta, GA 30329 USA.
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- Gaudet, Mia M (author)
- Amer Canc Soc, Epidemiol Res Program, Atlanta, GA 30329 USA.
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- Albanes, Demetrius (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Weinstein, Stephanie J (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Virtamo, Jarmo (author)
- Natl Inst Hlth & Welf, Dept Chron Dis Prevent, Helsinki, Finland.
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- Taylor, Philip R (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Freedman, Neal D (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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Abnet, Christian C (author)
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- Goldstein, Alisa M (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Hu, Nan (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.,Chinese Acad Med Sci, Dept Epidemiol, Canc Inst Hosp, Beijing 100730, Peoples R China.
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- Yu, Kai (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Yuan, Jian-Min (author)
- Univ Minnesota, Sch Publ Hlth, Dept Epidemiol & Community Hlth, Minneapolis, MN USA.;Univ Pittsburgh, Inst Canc, Pittsburgh, PA USA.
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- Liao, Linda (author)
- Harvard Univ, Sch Med, Channing Lab, Dept Med,Brigham & Womens Hosp, Boston, MA 02115 USA.;Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA.;Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA.,Mt Sinai Hosp, Samuel Lunenfeld Res Inst, Fred A Litwin Ctr Canc Genet, Toronto, ON M5G 1X5, Canada.;Mt Sinai Hosp, Christopher Sharp Ctr Surg & Oncol, Toronto, ON M5G 1X5, Canada.,Wayne State Univ, Dept Family Med & Publ Hlth Sci, Detroit, MI USA.,Walter Reed Army Inst Res, Silver Spring, MD USA.
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- Ding, Ti (author)
- Shanxi Canc Hosp, Taiyuan, Peoples R China.
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- Qiao, You-Lin (author)
- Chinese Acad Med Sci, Dept Epidemiol, Canc Inst Hosp, Beijing 100730, Peoples R China.
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- Gao, Yu-Tang (author)
- Shanghai Canc Inst, Shanghai, Peoples R China.
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- Koh, Woon-Puay (author)
- Natl Univ Singapore, Saw Swee Hock Sch Publ Hlth, Singapore 117548, Singapore.
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- Xiang, Yong-Bing (author)
- Shanghai Canc Inst, Shanghai, Peoples R China.
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- Tang, Ze-Zhong (author)
- Shanxi Canc Hosp, Taiyuan, Peoples R China.
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Fan, Jin-Hu (author)
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Aldrich, Melinda C (author)
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- Amos, Christopher (author)
- Univ Texas MD Anderson Canc Ctr, Dept Epidemiol, Div Canc Prevent & Populat Sci, Houston, TX 77030 USA.,Univ So Calif, Keck Sch Med, Dept Prevent Med, Norris Comprehens Canc Ctr, Los Angeles, CA 90033 USA.
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- Blot, William J (author)
- Vanderbilt Univ, Med Ctr, Dept Med, Div Epidemiol,Vanderbilt Epidemiol Ctr, Nashville, TN USA.;Int Epidemiol Inst, Rockville, MD USA.
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- Bock, Cathryn H (author)
- Wayne State Univ, Karmanos Canc Inst, Detroit, MI USA.;Wayne State Univ, Sch Med, Dept Oncol, Detroit, MI USA.
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- Gillanders, Elizabeth M (author)
- NCI, Div Canc Control & Populat Sci, Bethesda, MD 20892 USA.
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Harris, Curtis C (author)
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- Haiman, Christopher A (author)
- Karolinska Institutet
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- Henderson, Brian E (author)
- Univ So Calif, Keck Sch Med, Dept Prevent Med, Norris Comprehens Canc Ctr, Los Angeles, CA 90033 USA.
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- Kolonel, Laurence N (author)
- Univ Hawaii, Ctr Canc, Program Epidemiol, Honolulu, HI 96822 USA.
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- Le Marchand, Loic (author)
- Univ Hawaii, Ctr Canc, Program Epidemiol, Honolulu, HI 96822 USA.
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- McNeill, Lorna H (author)
- Univ Texas MD Anderson Canc Ctr, Dept Hlth Dispar Res, Div Off Vice President Canc Prevent & Populat Sci, Houston, TX 77030 USA.;Univ Texas MD Anderson Canc Ctr, Ctr Community Engaged & Translat Res, Duncan Family Inst, Houston, TX 77030 USA.
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- Rybicki, Benjamin A (author)
- Henry Ford Hosp, Dept Publ Hlth Sci, Detroit, MI 48202 USA.
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- Schwartz, Ann G (author)
- Wayne State Univ, Karmanos Canc Inst, Detroit, MI USA.;Wayne State Univ, Sch Med, Dept Oncol, Detroit, MI USA.
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- Signorello, Lisa B (author)
- Vanderbilt Univ, Med Ctr, Dept Med, Div Epidemiol,Vanderbilt Epidemiol Ctr, Nashville, TN USA.;Int Epidemiol Inst, Rockville, MD USA.;Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Nashville, TN 37212 USA.
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- Spitz, Margaret R (author)
- Baylor Coll Med, Dan L Duncan Canc Ctr, Houston, TX 77030 USA.
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- Wiencke, John K (author)
- Univ Calif San Francisco, Dept Neurol Surg, San Francisco, CA USA.
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- Wrensch, Margaret (author)
- Univ Calif San Francisco, Dept Neurol Surg, San Francisco, CA USA.
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- Wu, Xifeng (author)
- Univ Texas MD Anderson Canc Ctr, Dept Epidemiol, Div Canc Prevent & Populat Sci, Houston, TX 77030 USA.
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- Zanetti, Krista A (author)
- NCI, Div Canc Control & Populat Sci, Bethesda, MD 20892 USA.;NCI, Human Carcinogenesis Lab, Ctr Canc Res, Bethesda, MD 20892 USA.
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- Ziegler, Regina G (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Figueroa, Jonine D (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Garcia-Closas, Montserrat (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.;Inst Canc Res, Div Genet & Epidemiol, London SW3 6JB, England.
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- Malats, Nuria (author)
- CNIO, Genet & Mol Epidemiol Grp, Madrid, Spain.
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- Marenne, Gaelle (author)
- CNIO, Genet & Mol Epidemiol Grp, Madrid, Spain.
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- Prokunina-Olsson, Ludmila (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Baris, Dalsu (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Schwenn, Molly (author)
- Maine Canc Registry, Augusta, ME USA.
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- Johnson, Alison (author)
- Vermont Canc Registry, Burlington, VT USA.
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- Landi, Maria Teresa (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Goldin, Lynn (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Consonni, Dario (author)
- Univ Milan, Dept Occupat & Environm Hlth, Milan, Italy.;Osped Maggiore Policlin Mangiagalli & Regina Elen, Unit Epidemiol, Fdn Ist Ricevero & Cura Carattere Sci IRCCS, Milan, Italy.
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- Bertazzi, Pier Alberto (author)
- Univ Milan, Dept Occupat & Environm Hlth, Milan, Italy.;Osped Maggiore Policlin Mangiagalli & Regina Elen, Unit Epidemiol, Fdn Ist Ricevero & Cura Carattere Sci IRCCS, Milan, Italy.
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- Rotunno, Melissa (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Rajaraman, Preetha (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Andersson, Ulrika (author)
- Umeå universitet,Onkologi,Umeå Univ, Dept Radiat Sci, Umeå, Sweden.
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- Freeman, Laura E Beane (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Berg, Christine D (author)
- NCI, Clin & Translat Epidemiol Branch, Div Canc Control & Populat Sci, Bethesda, MD 20892 USA.
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- Buring, Julie E (author)
- Harvard Univ, Sch Med, Dept Ambulatory Care & Prevent, Boston, MA USA.;Harvard Univ, Brigham & Womens Hosp, Div Prevent Med, Sch Med, Boston, MA 02115 USA.
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- Butler, Mary A (author)
- NIOSH, Ctr Dis Control & Prevent, Cincinnati, OH 45226 USA.
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- Carreon, Tania (author)
- NIOSH, Ctr Dis Control & Prevent, Cincinnati, OH 45226 USA.
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- Feychting, Maria (author)
- Karolinska Institutet
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- Ahlbom, Anders (author)
- Karolinska Institutet
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- Gaziano, J Michael (author)
- Harvard Univ, Brigham & Womens Hosp, Div Prevent Med, Sch Med, Boston, MA 02115 USA.;Harvard Univ, Sch Med, Div Aging, Brigham & Womens Hosp, Boston, MA 02115 USA.;Vet Affairs Boston Healthcare Syst, Geriatr Res Educ & Clin Ctr, Massachusetts Vet Epidemiol Res & Informat Ctr, Boston, MA USA.
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- Giles, Graham G (author)
- Canc Council Victoria, Canc Epidemiol Ctr, Melbourne, Vic, Australia.;Univ Melbourne, Ctr Mol Environm Genet & Analyt Epidemiol, Melbourne, Vic, Australia.,Mayo Clin, Dept Hlth Sci Res, Rochester, MN USA.,Yeshiva Univ, Albert Einstein Coll Med, Dept Mol Pharmacol, Bronx, NY USA.;Yeshiva Univ, Albert Einstein Coll Med, Dept Pediat, Bronx, NY USA.,Univ Illinois, Sch Publ Hlth, Div Epidemiol & Biostat, Chicago, IL USA.
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- Hallmans, Göran (author)
- Umeå universitet,Näringsforskning,Umeå Univ, Dept Publ Hlth & Clin Med, Umeå, Sweden.
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- Hankinson, Susan E (author)
- Harvard Univ, Sch Med, Channing Lab, Dept Med,Brigham & Womens Hosp, Boston, MA 02115 USA.
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- Hartge, Patricia (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Henriksson, Roger (author)
- Umeå universitet,Onkologi,Umeå Univ, Dept Radiat Sci, Umeå, Sweden.;Karolinska Univ Hosp, Dept Oncol, Stockholm, Sweden.
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- Inskip, Peter D (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Johansen, Christoffer (author)
- Danish Canc Soc, Inst Canc Epidemiol, Copenhagen, Denmark.
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- Landgren, Annelie (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- McKean-Cowdin, Roberta (author)
- Univ So Calif, Keck Sch Med, Dept Prevent Med, Norris Comprehens Canc Ctr, Los Angeles, CA 90033 USA.
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- Michaud, Dominique S (author)
- Univ London Imperial Coll Sci Technol & Med, Sch Publ Hlth, Div Epidemiol & Biostat, London, England.;Brown Univ, Div Biol & Med, Dept Epidemiol, Providence, RI 02912 USA.
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- Melin, Beatrice S (author)
- Umeå universitet,Onkologi,Umeå Univ, Dept Radiat Sci, Umeå, Sweden.
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- Peters, Ulrike (author)
- Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, Seattle, WA 98104 USA.;Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA.
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- Ruder, Avima M (author)
- NIOSH, Ctr Dis Control & Prevent, Cincinnati, OH 45226 USA.
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- Sesso, Howard D (author)
- Harvard Univ, Brigham & Womens Hosp, Div Prevent Med, Sch Med, Boston, MA 02115 USA.
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- Severi, Gianluca (author)
- Canc Council Victoria, Canc Epidemiol Ctr, Melbourne, Vic, Australia.;Univ Melbourne, Ctr Mol Environm Genet & Analyt Epidemiol, Melbourne, Vic, Australia.
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- Shu, Xiao-Ou (author)
- Vanderbilt Univ, Med Ctr, Dept Med, Div Epidemiol,Vanderbilt Epidemiol Ctr, Nashville, TN USA.;Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Nashville, TN 37212 USA.
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- Visvanathan, Kala (author)
- Johns Hopkins Univ, Dept Epidemiol, Bloomberg Sch Publ Hlth, Baltimore, MD USA.
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- White, Emily (author)
- Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, Seattle, WA 98104 USA.;Univ Washington, Dept Epidemiol, Seattle, WA 98195 USA.
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- Wolk, Alicja (author)
- Karolinska Inst, Inst Environm Med, Div Nutr Epidemiol, S-10401 Stockholm, Sweden.
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- Zeleniuch-Jacquotte, Anne (author)
- NYU, Dept Environm Med, Sch Med, Div Epidemiol, New York, NY 10016 USA.
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- Zheng, Wei (author)
- Vanderbilt Univ, Med Ctr, Dept Med, Div Epidemiol,Vanderbilt Epidemiol Ctr, Nashville, TN USA.;Vanderbilt Univ, Sch Med, Vanderbilt Ingram Canc Ctr, Nashville, TN 37212 USA.
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- Silverman, Debra T (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Kogevinas, Manolis (author)
- Natl Sch Publ Hlth, Athens, Greece.;Ctr Res Environm Epidemiol CREAL, Barcelona, Spain.;IMIM, Barcelona, Spain.;CIBERESP, Barcelona, Spain.
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- Gonzalez, Juan R (author)
- Ctr Res Environm Epidemiol CREAL, Barcelona, Spain.;IMIM, Barcelona, Spain.;CIBERESP, Barcelona, Spain.
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- Villa, Olaya (author)
- Univ Pompeu Fabra, Dept Ciencies Expt & Salut, Barcelona, Spain.;Ctr Invest Biomed Red Enfermedades Raras CIBERER, Barcelona, Spain.;qGenomics, Quantitat Genom Med Lab, Barcelona, Spain.
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- Li, Donghui (author)
- Univ Texas MD Anderson Canc Ctr, Dept Gastrointestinal Med Oncol, Houston, TX 77030 USA.
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- Duell, Eric J (author)
- Inst Invest Biomed Bellvitge IDIBELL, Catalan Inst Oncol ICO, Barcelona, Spain.
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Risch, Harvey A (author)
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- Olson, Sara H (author)
- Mem Sloan Kettering Canc Ctr, Dept Epidemiol & Biostat, New York, NY 10021 USA.
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- Kooperberg, Charles (author)
- Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, Seattle, WA 98104 USA.
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- Wolpin, Brian M (author)
- Harvard Univ, Sch Med, Channing Lab, Dept Med,Brigham & Womens Hosp, Boston, MA 02115 USA.;Dana Farber Canc Inst, Dept Med Oncol, Boston, MA 02115 USA.
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- Jiao, Li (author)
- Baylor Coll Med, Dept Med, Houston, TX 77030 USA.
-
- Hassan, Manal (author)
- Univ Texas MD Anderson Canc Ctr, Dept Gastrointestinal Med Oncol, Houston, TX 77030 USA.
-
- Wheeler, William (author)
- Informat Management Serv Inc, Silver Spring, MD USA.,NCI, Clin & Translat Epidemiol Branch, Div Canc Control & Populat Sci, Bethesda, MD 20892 USA.,NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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Arslan, Alan A (author)
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- Bueno-de-Mesquita, H Bas (author)
- Univ Med Ctr Utrecht, Dept Gastroenterol & Hepatol, Utrecht, Netherlands.;Natl Inst Publ Hlth & Environm RIVM, Bilthoven, Netherlands.
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- Fuchs, Charles S (author)
- Harvard Univ, Sch Med, Channing Lab, Dept Med,Brigham & Womens Hosp, Boston, MA 02115 USA.;Dana Farber Canc Inst, Dept Med Oncol, Boston, MA 02115 USA.
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- Gallinger, Steven (author)
- Mt Sinai Hosp, Samuel Lunenfeld Res Inst, Fred A Litwin Ctr Canc Genet, Toronto, ON M5G 1X5, Canada.
-
- Gross, Myron D (author)
- Univ Minnesota, Sch Med, Dept Lab Med & Pathol, Minneapolis, MN 55455 USA.
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Holly, Elizabeth A (author)
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- Klein, Alison P (author)
- Johns Hopkins Univ, Sch Med, Dept Oncol, Baltimore, MD 21205 USA.
-
- Lacroix, Andrea (author)
- Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, Seattle, WA 98104 USA.
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- Mandelson, Margaret T (author)
- Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, Seattle, WA 98104 USA.;Grp Hlth Ctr Hlth Studies, Seattle, WA USA.,NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Petersen, Gloria (author)
- Mayo Clin, Dept Hlth Sci Res, Rochester, MN USA.
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- Boutron-Ruault, Marie-Christine (author)
- Univ Paris Sud, INSERM, Inst Gustave Roussy, Villejuif, France.
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- Bracci, Paige M (author)
- Univ Calif San Francisco, Dept Epidemiol & Biostat, San Francisco, CA 94143 USA.
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- Canzian, Federico (author)
- German Canc Res Ctr, Div Canc Epidemiol, Heidelberg, Germany.
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- Chang, Kenneth (author)
- Univ Calif Irvine, Med Ctr, Comprehens Digest Dis Ctr, Orange, CA USA.
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- Cotterchio, Michelle (author)
- Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada.
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Giovannucci, Edward L (author)
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- Goggins, Michael (author)
- Johns Hopkins Univ, Sch Med, Dept Oncol, Baltimore, MD 21205 USA.;Johns Hopkins Univ, Sch Med, Dept Med, Baltimore, MD 21205 USA.;Johns Hopkins Univ, Sch Med, Dept Pathol, Baltimore, MD 21205 USA.
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Bolton, Judith A Hoffman (author)
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- Jenab, Mazda (author)
- Int Agcy Res Canc, World Hlth Org, F-69372 Lyon, France.
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- Khaw, Kay-Tee (author)
- Univ Cambridge, Addenbrookes Hosp, Dept Publ Hlth & Primary Care, Cambridge CB2 2QQ, England.
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- Krogh, Vittorio (author)
- Ist Nazl Tumori, IRCCS, Nutr Epidemiol Unit, I-20133 Milan, Italy.
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Kurtz, Robert C (author)
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- McWilliams, Robert R (author)
- Mayo Clin, Div Med Oncol, Rochester, MN USA.
-
- Mendelsohn, Julie B (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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Rabe, Kari G (author)
-
- Riboli, Elio (author)
- Univ London Imperial Coll Sci Technol & Med, Sch Publ Hlth, Div Epidemiol & Biostat, London, England.
-
- Tjønneland, Anne (author)
- Danish Canc Soc, Inst Canc Epidemiol, Copenhagen, Denmark.
-
- Tobias, Geoffrey S (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
-
- Trichopoulos, Dimitrios (author)
- Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA.;Acad Athens, Bur Epidemiol Res, Athens, Greece.
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Elena, Joanne W (author)
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- Yu, Herbert (author)
- Yale Univ, Sch Publ Hlth, New Haven, CT USA.
-
- Amundadottir, Laufey (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
-
- Stolzenberg-Solomon, Rachael Z (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
-
- Kraft, Peter (author)
- Harvard Univ, Sch Med, Channing Lab, Dept Med,Brigham & Womens Hosp, Boston, MA 02115 USA.;Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA.,NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.;Hannover Med Sch, Klin Padiatr Hematol & Onkol, Zentrum Kinderheilkunde & Jugendmed, D-30623 Hannover, Germany.
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- Schumacher, Fredrick (author)
- Univ So Calif, Keck Sch Med, Dept Prevent Med, Norris Comprehens Canc Ctr, Los Angeles, CA 90033 USA.
-
- Stram, Daniel (author)
- Univ So Calif, Keck Sch Med, Dept Prevent Med, Norris Comprehens Canc Ctr, Los Angeles, CA 90033 USA.
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Savage, Sharon A (author)
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Mirabello, Lisa (author)
-
Andrulis, Irene L (author)
-
- Wunder, Jay S (author)
- Mt Sinai Hosp, Samuel Lunenfeld Res Inst, Fred A Litwin Ctr Canc Genet, Toronto, ON M5G 1X5, Canada.;Mt Sinai Hosp, Christopher Sharp Ctr Surg & Oncol, Toronto, ON M5G 1X5, Canada.
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- García, Ana Patiño (author)
- Univ Navarra Clin, Dept Pediat, Pamplona, Spain.
-
- Sierrasesúmaga, Luis (author)
- Univ Navarra Clin, Dept Pediat, Pamplona, Spain.
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Barkauskas, Donald A (author)
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Gorlick, Richard G (author)
-
- Purdue, Mark (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Chow, Wong-Ho (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Moore, Lee E (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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Schwartz, Kendra L (author)
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Davis, Faith G (author)
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Hsing, Ann W (author)
-
- Berndt, Sonja I (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
-
- Black, Amanda (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
-
- Wentzensen, Nicolas (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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Brinton, Louise A (author)
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- Lissowska, Jolanta (author)
- Inst Oncol, Warsaw, Poland.;Maria Sklodowska Curie Mem Canc Ctr, Warsaw, Poland.
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- Peplonska, Beata (author)
- Nofer Inst Occupat Med, Lodz, Poland.
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McGlynn, Katherine A (author)
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- Cook, Michael B (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Graubard, Barry I (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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Kratz, Christian P (author)
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- Greene, Mark H (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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Erickson, Ralph L (author)
-
- Hunter, David J (author)
- Harvard Univ, Sch Med, Channing Lab, Dept Med,Brigham & Womens Hosp, Boston, MA 02115 USA.;Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA.
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- Thomas, Gilles (author)
- Univ Lyon 1, Ctr Leon Berard, F-69365 Lyon, France.
-
- Hoover, Robert N (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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- Real, Francisco X (author)
- Univ Pompeu Fabra, Dept Ciencies Expt & Salut, Barcelona, Spain.;CNIO, Epithelial Carcinogenesis Grp, Madrid, Spain.
-
- Fraumeni, Joseph F, Jr (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
-
- Caporaso, Neil E (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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Tucker, Margaret (author)
-
- Rothman, Nathaniel (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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Pérez-Jurado, Luis A (author)
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- Chanock, Stephen J (author)
- NCI, Div Canc Epidemiol & Genet, Rockville, MD USA.
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NCI, Div Canc Epidemiol & Genet, Rockville, MD USA;NCI, Core Genotyping Facil, SAIC Frederick Inc, Frederick, MD 21701 USA. NCI, Div Canc Epidemiol & Genet, Rockville, MD USA. (creator_code:org_t)
- 2012-05-06
- 2012
- English.
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In: Nature Genetics. - New York : Nature Publishing Group. - 1061-4036 .- 1546-1718. ; 44:6, s. 651-658
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Abstract
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- In an analysis of 31,717 cancer cases and 26,136 cancer-free controls from 13 genome-wide association studies, we observed large chromosomal abnormalities in a subset of clones in DNA obtained from blood or buccal samples. We observed mosaic abnormalities, either aneuploidy or copy-neutral loss of heterozygosity, of >2 Mb in size in autosomes of 517 individuals (0.89%), with abnormal cell proportions of between 7% and 95%. In cancer-free individuals, frequency increased with age, from 0.23% under 50 years to 1.91% between 75 and 79 years (P = 4.8 × 10(-8)). Mosaic abnormalities were more frequent in individuals with solid tumors (0.97% versus 0.74% in cancer-free individuals; odds ratio (OR) = 1.25; P = 0.016), with stronger association with cases who had DNA collected before diagnosis or treatment (OR = 1.45; P = 0.0005). Detectable mosaicism was also more common in individuals for whom DNA was collected at least 1 year before diagnosis with leukemia compared to cancer-free individuals (OR = 35.4; P = 3.8 × 10(-11)). These findings underscore the time-dependent nature of somatic events in the etiology of cancer and potentially other late-onset diseases.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Medicinsk genetik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Medical Genetics (hsv//eng)
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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and Medical Genetics
- Articles in the publication
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Nature Genetics
- By the university
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Umeå University
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Uppsala University
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Karolinska Institutet