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Increased free andr...
Increased free androgen index is associated with hypertension in premenopausal women
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Andersson, Liselott (author)
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- Eliasson, Mats (author)
- Umeå universitet,Medicin
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Sundström Poromaa, Inger (author)
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(creator_code:org_t)
- Scientific Research Publishing, 2011
- 2011
- English.
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In: Open Journal of Obstetrics and Gynecology. - : Scientific Research Publishing. - 2160-8792 .- 2160-8806. ; 1, s. 228-233
- Related links:
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http://www.scirp.org...
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https://urn.kb.se/re...
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https://doi.org/10.4...
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Abstract
Subject headings
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- Objective: Increased testosterone and decreased sex hormone-binding globulin (SHBG) are associated with a number of adverse cardiovascular risk factors in postmenopausal women. The aim of this popula-tion-based study of women aged 25 to 50 was to as-sess the relationship between free androgen index (FAI) and cardiovascular risk factors in premeno-pausal women.Methods: A population-based survey of 396 premenopausal women with no hormonal trea- tment was undertaken as part of the Northern Swe-den MONICA study. The study involved question-naires, anthropometry and assays of testosterone and SHBG.Results: Increased FAI was associated with a number of cardiovascular risk factors in premeno-pausal women but this relationship was strongly af-fected by body mass index (BMI). After adjustment for age and BMI, FAI was significantly associated with increased systolic and diastolic blood pressures.Conclusion: Hyperandrogenism is associated with increased blood pressure and these findings empha-size the need to assess cardiovascular risk factors in women with hyperandrogenism of all ages.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Allmänmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- General Practice (hsv//eng)
Keyword
- Free Androgen Index
- Blood Pressure
Publication and Content Type
- ref (subject category)
- art (subject category)
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