Search: WFRF:(Crowe Francesca L.) >
Age at Menopause, R...
Age at Menopause, Reproductive Life Span, and Type 2 Diabetes Risk
-
Brand, Judith S. (author)
-
van der Schouw, Yvonne T. (author)
-
Onland-Moret, N. Charlotte (author)
-
show more...
-
Sharp, Stephen J. (author)
-
Ong, Ken K. (author)
-
Khaw, Kay-Tee (author)
-
Ardanaz, Eva (author)
-
Amiano, Pilar (author)
-
Boeing, Heiner (author)
-
Chirlaque, Maria-Dolores (author)
-
Clavel-Chapelon, Francoise (author)
-
Crowe, Francesca L. (author)
-
de Lauzon-Guillain, Blandine (author)
-
Duell, Eric J. (author)
-
Fagherazzi, Guy (author)
-
- Franks, Paul W. (author)
- Lund University,Lunds universitet,Umeå universitet,Medicin,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups
-
Grioni, Sara (author)
-
- Groop, Leif (author)
- Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups
-
Kaaks, Rudolf (author)
-
Key, Timothy J. (author)
-
- Nilsson, Peter (author)
- Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups
-
Overvad, Kim (author)
-
Palli, Domenico (author)
-
Panico, Salvatore (author)
-
Quiros, J. Ramon (author)
-
- Rolandsson, Olov (author)
- Umeå universitet,Allmänmedicin
-
Sacerdote, Carlotta (author)
-
Sanchez, Maria-Jose (author)
-
Slimani, Nadia (author)
-
Teucher, Birgit (author)
-
Tjonneland, Anne (author)
-
Tumino, Rosario (author)
-
van der A, Daphne L. (author)
-
Feskens, Edith J. M. (author)
-
Langenberg, Claudia (author)
-
Forouhi, Nita G. (author)
-
Riboli, Elio (author)
-
Wareham, Nicholas J. (author)
-
show less...
-
(creator_code:org_t)
- 2013-03-14
- 2013
- English.
-
In: Diabetes Care. - : American Diabetes Association. - 0149-5992 .- 1935-5548. ; 36:4, s. 1012-1019
- Related links:
-
https://care.diabete...
-
show more...
-
http://dx.doi.org/10...
-
https://urn.kb.se/re...
-
https://doi.org/10.2...
-
https://lup.lub.lu.s...
-
show less...
Abstract
Subject headings
Close
- OBJECTIVE-Age at menopause is an important determinant of future health outcomes, but little is known about its relationship with type 2 diabetes. We examined the associations of menopausal age and reproductive life span (menopausal age minus menarcheal age) with diabetes risk.RESEARCH DESIGN AND METHODS-Data were obtained from the InterAct study, a prospective case-cohort study nested within the European Prospective Investigation into Cancer and Nutrition. A total of 3,691 postmenopausal type 2 diabetic case subjects and 4,408 subcohort members were included in the analysis, with a median follow-up of 11 years. Prentice weighted Cox proportional hazards models were adjusted for age, known risk factors for diabetes, and reproductive factors, and effect modification by BMI, waist circumference, and smoking was studied.RESULTS-Mean (SD) age of the subcohort was 59.2 (5.8) years. After multivariable adjustment, hazard ratios (HRs) of type 2 diabetes were 1.32 (95% CI 1.04-1.69), 1.09 (0.90-1.31), 0.97 (0.86-1.10), and 0.85 (0.70-1.03) for women with menopause at ages <40, 40-44, 45-49, and >= 55 years, respectively, relative to those with menopause at age 50-54 years. The HR per SD younger age at menopause was 1.08 (1.02-1.14). Similarly, a shorter reproductive life span was associated with a higher diabetes risk (HR per SD lower reproductive life span 1.06 [ 1.01-1.12]). No effect modification by BMI, waist circumference, or smoking was observed (P interaction all > 0.05).CONCLUSIONS-Early menopause is associated with a greater risk of type 2 diabetes. Diabetes Care 36:1012-1019, 2013
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database
- By the author/editor
-
Brand, Judith S.
-
van der Schouw, ...
-
Onland-Moret, N. ...
-
Sharp, Stephen J ...
-
Ong, Ken K.
-
Khaw, Kay-Tee
-
show more...
-
Ardanaz, Eva
-
Amiano, Pilar
-
Boeing, Heiner
-
Chirlaque, Maria ...
-
Clavel-Chapelon, ...
-
Crowe, Francesca ...
-
de Lauzon-Guilla ...
-
Duell, Eric J.
-
Fagherazzi, Guy
-
Franks, Paul W.
-
Grioni, Sara
-
Groop, Leif
-
Kaaks, Rudolf
-
Key, Timothy J.
-
Nilsson, Peter
-
Overvad, Kim
-
Palli, Domenico
-
Panico, Salvator ...
-
Quiros, J. Ramon
-
Rolandsson, Olov
-
Sacerdote, Carlo ...
-
Sanchez, Maria-J ...
-
Slimani, Nadia
-
Teucher, Birgit
-
Tjonneland, Anne
-
Tumino, Rosario
-
van der A, Daphn ...
-
Feskens, Edith J ...
-
Langenberg, Clau ...
-
Forouhi, Nita G.
-
Riboli, Elio
-
Wareham, Nichola ...
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Clinical Medicin ...
-
and Endocrinology an ...
- Articles in the publication
-
Diabetes Care
- By the university
-
Umeå University
-
Lund University