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- Brämerson, Annika,1960Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för öron-, näs- och halssjukdomar,Institute of Clinical Sciences, Department of Otorhinolaryngology (author)
Olfactory loss after head and neck cancer radiation therapy
- Article/chapterEnglish2013
Publisher, publication year, extent ...
- 2013
- printrdacarrier
Numbers
- LIBRIS-ID:oai:DiVA.org:umu-81478
- https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-81478URI
- https://doi.org/10.4193/Rhino12.120DOI
- https://gup.ub.gu.se/publication/188584URI
Supplementary language notes
- Language:English
- Summary in:English
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- SwePubSwePub
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Notes
- BACKGROUND: A reduced sense of smell may be one explanation for why patients with cancer in the ear, nose and throat (ENT) region who are treated with radiation therapy lose weight. The purpose of this study was to investigate whether radiation therapy has a negative effect on olfactory function and, if so, whether this effect is dose-related.METHODOLOGY: Seventy-one patients were tested using odour-detection sensitivity and olfactory identification tests before radiation therapy and 20 months after it.RESULTS: Patients who received radiation close to the olfactory organ showed a reduced sense of smell, in both tests. A multiple regression analysis showed that the radiation dose was related to decline in the olfactory function, while age, sex, chemotherapy and interactions between these variables were not.CONCLUSION: Radiation therapy can damage olfactory cells.
Subject headings and genre
- SAMHÄLLSVETENSKAP Psykologi hsv//swe
- SOCIAL SCIENCES Psychology hsv//eng
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Oto-rhino-laryngologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Otorhinolaryngology hsv//eng
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Cancer och onkologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Cancer and Oncology hsv//eng
- smell/radiation effects
- radiotherapy/adverse effects
- head and neck neoplasms
- humans
- adults
Added entries (persons, corporate bodies, meetings, titles ...)
- Nyman, Jan,1956Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för onkologi,Institute of Clinical Sciences, Department of Oncology(Swepub:gu)xnymja (author)
- Nordin, StevenUmeå universitet,Institutionen för psykologi(Swepub:umu)stno0002 (author)
- Bende, Mats,1947Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för öron-, näs- och halssjukdomar,Institute of Clinical Sciences, Department of Otorhinolaryngology(Swepub:gu)xbendm (author)
- Göteborgs universitetInstitutionen för kliniska vetenskaper, Avdelningen för öron-, näs- och halssjukdomar (creator_code:org_t)
Related titles
- In:Rhinology51:3, s. 206-2090300-07291996-8604
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