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n-3 Fatty acids are...
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Högström, MagnusUmeå universitet,Idrottsmedicin
(author)
n-3 Fatty acids are positively associated with peak bone mineral density and bone accrual in healthy men : the NO2 Study
- Article/chapterEnglish2007
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American Society for Clinical Nutrition,2007
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LIBRIS-ID:oai:DiVA.org:umu-8330
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-8330URI
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
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Background:Knowledge of the influence of nutritional intake on bone health is limited. Polyunsaturated fatty acids have been suggested to influence bone growth and modeling in humans, although data are sparse.Objective:The objective was to investigate the role of fatty acids in bone accumulation and the attainment of peak bone mass in young men.Design:The cohort studied consisted of 78 healthy young men with a mean age of 16.7 y at baseline. Bone mineral density (BMD; in g/cm2) of total body, hip, and spine was measured at baseline and at 22 and 24 y of age. Fatty acid concentrations were measured in the phospholipid fraction in serum at 22 y of age.Results:Concentrations of n−3 fatty acids were positively associated with total BMD (r = 0.27, P = 0.02) and spine BMD (r = 0.25, P = 0.02) at 22 y of age. A positive correlation between n−3 fatty acid concentrations and the changes in BMD at the spine (r = 0.26, P = 0.02) was found between 16 and 22 y of age. Concentrations of docosahexaenoic acid (DHA, 22:6n−3) were positively associated with total BMD (r = 0.32, P = 0.004) and BMD at the spine (r = 0.30, P = 0.008) at 22 y of age. A positive correlation was also found between DHA concentrations and the changes in BMD at the spine (r = 0.26, P = 0.02) between 16 and 22 y of age.Conclusion:The results showed that n−3 fatty acids, especially DHA, are positively associated with bone mineral accrual and, thus, with peak BMD in young men.
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Nordström, PeterUmeå universitet,Idrottsmedicin,Institutionen för folkhälsa och klinisk medicin(Swepub:umu)peno0014
(author)
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Nordström, AnnaUmeå universitet,Idrottsmedicin,Institutionen för samhällsmedicin och rehabilitering(Swepub:umu)anagun97
(author)
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Umeå universitetIdrottsmedicin
(creator_code:org_t)
Related titles
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In:American Journal of Clinical Nutrition: American Society for Clinical Nutrition85:3, s. 803-8070002-91651938-3207
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