id:"swepub:oai:DiVA.org:umu-8752"
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- Karling, PontusUmeå universitet,Medicin (author)
No difference in symptoms of irritable bowel syndrome between healthy subjects and patients with recurrent depression in remission
- Article/chapterEnglish2007
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- Oxford :Blackwell,2007
- printrdacarrier
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- LIBRIS-ID:oai:DiVA.org:umu-8752
- https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-8752URI
- https://doi.org/10.1111/j.1365-2982.2007.00967.xDOI
Supplementary language notes
- Language:English
- Summary in:English
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- There is bidirectional comorbidity between anxiety/depression and irritable bowel syndrome (IBS). To investigate the prevalence of IBS symptoms, and factors associated with gastrointestinal symptoms in patients with recurrent depressive disorder. Patients (n = 95) with recurrent type of major depression according to DSM-IV criteria and sex- and age-matched controls (n = 190) were sent questionnaires investigating symptoms of IBS [Gastrointestinal Symptom Rating Scale (GSRS)-IBS] and symptoms of anxiety and depression [Hospital Anxiety and Depression Scale (HADS)]. Medical records were checked over a 10-year period for chronic somatic symptoms or diseases. Seventy-three patients with unipolar disorder (mean age 63.6 years SD 13.8; range 23–86 years) and 156 controls (mean age 59.2 years SD 11.6, range 21–85 years) responded. Patients with recurrent depression had higher GSRS-IBS scores and showed a strong correlation between symptoms of IBS and anxiety-depression (rs = 0.54; P < 0.001). IBS symptoms were also associated with multiple pain symptoms, higher health-seeking behaviour and selective-serotonin-reuptake inhibitor intake. However, patients with recurrent depression (n = 46) in remission (HADS-Depression score <8) did not have more symptoms of IBS than controls (GSRS-IBS median score 6.0 vs 6.5; P = 0.46). There is a strong association between symptoms of IBS and symptoms of anxiety and depression, whereas depressive patients in remission do not have more IBS symptoms than controls.
Subject headings and genre
- adult
- aged
- aged; 80 and over
- anxiety/complications/physiopathology
- case-control studies
- depression/*complications/*physiopathology/psychology
- female
- health surveys
- humans
- irritable bowel syndrome/*complications/*physiopathology/psychology
- male
- middle aged
- prevalence
- recurrence
- remission; spontaneous
- severity of illness index
Added entries (persons, corporate bodies, meetings, titles ...)
- Danielsson, ÅkeUmeå universitet,Medicin(Swepub:umu)akda0001 (author)
- Adolfsson, RolfUmeå universitet,Psykiatri(Swepub:umu)road0001 (author)
- Norrback, Karl-FredrikUmeå universitet,Psykiatri(Swepub:umu)kaknok96 (author)
- Umeå universitetMedicin (creator_code:org_t)
Related titles
- In:Neurogastroenterology and MotilityOxford : Blackwell19:11, s. 896-9041350-19251365-2982
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